C4B_2 (complement component 4B (Chido/Rodgers blood group), copy 2)

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Gene Gene information from NCBI Gene database.
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Entrez ID 100293534
Gene name Complement component 4B (Chido/Rodgers blood group), copy 2
Gene symbol C4B_2
Synonyms (NCBI Gene)
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Chromosome 6
Chromosome location 6p21.3 alternate reference locus
Summary This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC 42398 N/A
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
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KEGG Pathway Reactome Pathway
Complement and coagulation cascades Initial triggering of complement
Alcoholic liver disease Activation of C3 and C5
Pertussis Regulation of Complement cascade
Staphylococcus aureus infection  
Coronavirus disease - COVID-19  
Systemic lupus erythematosus  
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C2 9 shared pathwaysComplement and coagulation cascades, Alcoholic liver disease, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus, Initial triggering of complement, Activation of C3 and C5, Regulation of Complement cascade Related via 9 shared pathways including Complement and coagulation cascades, Alcoholic liver disease. C4A 9 shared pathwaysComplement and coagulation cascades, Alcoholic liver disease, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus, Initial triggering of complement, Activation of C3 and C5, Regulation of Complement cascade Related via 9 shared pathways including Complement and coagulation cascades, Alcoholic liver disease. C4B 9 shared pathwaysComplement and coagulation cascades, Alcoholic liver disease, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus, Initial triggering of complement, Activation of C3 and C5, Regulation of Complement cascade Related via 9 shared pathways including Complement and coagulation cascades, Alcoholic liver disease. C1S 7 shared pathwaysComplement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus, Initial triggering of complement, Regulation of Complement cascade Related via 7 shared pathways including Complement and coagulation cascades, Pertussis. LOC110384692 6 shared pathwaysComplement and coagulation cascades, Alcoholic liver disease, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Related via 6 shared pathways including Complement and coagulation cascades, Alcoholic liver disease.
Complement pathway abnormality Linked via 4 of 5 related genesC2, C4A, C4B, C1S Complement component deficiency Linked via 4 of 5 related genesC2, C4A, C4B, C1S Systemic lupus erythematosus Linked via 3 of 5 related genesC2, C4A, C4B Alzheimer disease Linked via 2 of 5 related genesC2, C1S Autism Linked via 2 of 5 related genesC2, C4B