BMP8B (bone morphogenetic protein 8b)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 656 |
| Gene name | Bone morphogenetic protein 8b |
| Gene symbol | BMP8B |
| Synonyms (NCBI Gene) |
BMP8OP2
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| Chromosome | 1 |
| Chromosome location | 1p34.2 |
| Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P34820 | |||||||||||||||
| Protein name | Bone morphogenetic protein 8B (BMP-8) (BMP-8B) (Osteogenic protein 2) (OP-2) | |||||||||||||||
| Protein function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
MTALPGPLWLLGLALCALGGGGPGLRPPPGCPQRRLGARERRDVQREILAVLGLPGRPRP |
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| Sequence length | 402 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with BMP8B across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to BMP8B (see Related Genes above), that are NOT already directly curated for BMP8B itself -- a lead worth checking, not a confirmed association.
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