ARHGAP29 (Rho GTPase activating protein 29)

Gene

• Entrez ID: 9411
• Gene name: Rho GTPase activating protein 29
• Gene symbol: ARHGAP29
• Synonyms (NCBI Gene): PARG1
• Chromosome: 1
• Chromosome location: 1p22.1-p21.3
• Summary: Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for R

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1114167280	C>G	Pathogenic	Splice acceptor variant
rs1114167281	G>T	Pathogenic	Stop gained, coding sequence variant
rs1114167282	C>T	Pathogenic	Splice donor variant
rs1570497770	C>T	Pathogenic	Splice donor variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT003762	hsa-miR-1-3p	Microarray	15685193
MIRT004075	hsa-miR-124-3p	Microarray	15685193
MIRT005817	hsa-miR-204-5p	Microarray	21282569
MIRT004075	hsa-miR-124-3p	Microarray	15685193
MIRT003762	hsa-miR-1-3p	Microarray	15685193
MIRT024335	hsa-miR-215-5p	Microarray	19074876
MIRT026359	hsa-miR-192-5p	Microarray	19074876
MIRT660552	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT660551	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT660550	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT660549	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT660548	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT660547	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT660546	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT660545	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT660544	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT660543	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT660542	hsa-miR-4284	HITS-CLIP	23824327
MIRT660541	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT660540	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT442544	hsa-miR-3936	PAR-CLIP	22100165
MIRT442545	hsa-miR-6782-5p	PAR-CLIP	22100165
MIRT442543	hsa-miR-3163	PAR-CLIP	22100165
MIRT442542	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT442541	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT442540	hsa-miR-6083	PAR-CLIP	22100165
MIRT442544	hsa-miR-3936	PAR-CLIP	22100165
MIRT442545	hsa-miR-6782-5p	PAR-CLIP	22100165
MIRT442543	hsa-miR-3163	PAR-CLIP	22100165
MIRT442542	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT442541	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT442540	hsa-miR-6083	PAR-CLIP	22100165
MIRT660552	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT660551	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT660550	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT660549	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT660548	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT660547	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT660546	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT660545	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT660544	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT660543	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT660542	hsa-miR-4284	HITS-CLIP	23824327
MIRT660541	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT660540	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT442544	hsa-miR-3936	PAR-CLIP	22100165
MIRT442545	hsa-miR-6782-5p	PAR-CLIP	22100165
MIRT442543	hsa-miR-3163	PAR-CLIP	22100165
MIRT442542	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT442541	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT442540	hsa-miR-6083	PAR-CLIP	22100165
MIRT442544	hsa-miR-3936	PAR-CLIP	22100165
MIRT442545	hsa-miR-6782-5p	PAR-CLIP	22100165
MIRT442543	hsa-miR-3163	PAR-CLIP	22100165
MIRT442542	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT442541	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT442540	hsa-miR-6083	PAR-CLIP	22100165
MIRT794376	hsa-miR-1236	CLIP-seq
MIRT794377	hsa-miR-1252	CLIP-seq
MIRT794378	hsa-miR-1266	CLIP-seq
MIRT794379	hsa-miR-1297	CLIP-seq
MIRT794380	hsa-miR-1298	CLIP-seq
MIRT794381	hsa-miR-1323	CLIP-seq
MIRT794382	hsa-miR-1343	CLIP-seq
MIRT794383	hsa-miR-2278	CLIP-seq
MIRT794384	hsa-miR-26a	CLIP-seq
MIRT794385	hsa-miR-26b	CLIP-seq
MIRT794386	hsa-miR-3123	CLIP-seq
MIRT794387	hsa-miR-3128	CLIP-seq
MIRT794388	hsa-miR-3137	CLIP-seq
MIRT794389	hsa-miR-3148	CLIP-seq
MIRT794390	hsa-miR-3664-3p	CLIP-seq
MIRT794391	hsa-miR-3686	CLIP-seq
MIRT794392	hsa-miR-3692	CLIP-seq
MIRT794393	hsa-miR-3919	CLIP-seq
MIRT794394	hsa-miR-3925-5p	CLIP-seq
MIRT794395	hsa-miR-3976	CLIP-seq
MIRT794396	hsa-miR-4282	CLIP-seq
MIRT794397	hsa-miR-4465	CLIP-seq
MIRT794398	hsa-miR-4470	CLIP-seq
MIRT794399	hsa-miR-4495	CLIP-seq
MIRT794400	hsa-miR-4496	CLIP-seq
MIRT794401	hsa-miR-4518	CLIP-seq
MIRT794402	hsa-miR-4652-3p	CLIP-seq
MIRT794403	hsa-miR-4668-5p	CLIP-seq
MIRT794404	hsa-miR-4670-3p	CLIP-seq
MIRT794405	hsa-miR-4712-3p	CLIP-seq
MIRT794406	hsa-miR-4717-3p	CLIP-seq
MIRT794407	hsa-miR-4760-3p	CLIP-seq
MIRT794408	hsa-miR-513a-3p	CLIP-seq
MIRT794409	hsa-miR-520d-5p	CLIP-seq
MIRT794410	hsa-miR-524-5p	CLIP-seq
MIRT794411	hsa-miR-543	CLIP-seq
MIRT794412	hsa-miR-548a-3p	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794418	hsa-miR-548e	CLIP-seq
MIRT794419	hsa-miR-548f	CLIP-seq
MIRT794420	hsa-miR-548o	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT794423	hsa-miR-556-3p	CLIP-seq
MIRT794424	hsa-miR-579	CLIP-seq
MIRT794425	hsa-miR-587	CLIP-seq
MIRT794426	hsa-miR-656	CLIP-seq
MIRT794427	hsa-miR-664	CLIP-seq
MIRT1934446	hsa-miR-1303	CLIP-seq
MIRT794382	hsa-miR-1343	CLIP-seq
MIRT1934447	hsa-miR-145	CLIP-seq
MIRT1934448	hsa-miR-1976	CLIP-seq
MIRT794389	hsa-miR-3148	CLIP-seq
MIRT1934449	hsa-miR-3157-3p	CLIP-seq
MIRT1934450	hsa-miR-3180-5p	CLIP-seq
MIRT1934451	hsa-miR-33a	CLIP-seq
MIRT1934452	hsa-miR-33b	CLIP-seq
MIRT1934453	hsa-miR-370	CLIP-seq
MIRT794393	hsa-miR-3919	CLIP-seq
MIRT1934454	hsa-miR-3978	CLIP-seq
MIRT1934455	hsa-miR-4263	CLIP-seq
MIRT1934456	hsa-miR-4423-5p	CLIP-seq
MIRT1934457	hsa-miR-4729	CLIP-seq
MIRT1934458	hsa-miR-485-3p	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT1934459	hsa-miR-617	CLIP-seq
MIRT1934460	hsa-miR-874	CLIP-seq
MIRT1934461	hsa-miR-938	CLIP-seq
MIRT2174240	hsa-miR-105	CLIP-seq
MIRT2174241	hsa-miR-1185	CLIP-seq
MIRT2174242	hsa-miR-1273d	CLIP-seq
MIRT2174243	hsa-miR-132	CLIP-seq
MIRT794382	hsa-miR-1343	CLIP-seq
MIRT1934447	hsa-miR-145	CLIP-seq
MIRT2174244	hsa-miR-1825	CLIP-seq
MIRT2174245	hsa-miR-1827	CLIP-seq
MIRT2174246	hsa-miR-199a-5p	CLIP-seq
MIRT2174247	hsa-miR-199b-5p	CLIP-seq
MIRT2174248	hsa-miR-212	CLIP-seq
MIRT2174249	hsa-miR-3065-5p	CLIP-seq
MIRT2174250	hsa-miR-3074-3p	CLIP-seq
MIRT2174251	hsa-miR-3156-5p	CLIP-seq
MIRT2174252	hsa-miR-3162-5p	CLIP-seq
MIRT2174253	hsa-miR-3174	CLIP-seq
MIRT1934451	hsa-miR-33a	CLIP-seq
MIRT1934452	hsa-miR-33b	CLIP-seq
MIRT2174254	hsa-miR-340	CLIP-seq
MIRT2174255	hsa-miR-3614-3p	CLIP-seq
MIRT2174256	hsa-miR-3622a-5p	CLIP-seq
MIRT2174257	hsa-miR-3661	CLIP-seq
MIRT2174258	hsa-miR-3671	CLIP-seq
MIRT2174259	hsa-miR-3672	CLIP-seq
MIRT2174260	hsa-miR-3679-5p	CLIP-seq
MIRT2174261	hsa-miR-374c	CLIP-seq
MIRT794393	hsa-miR-3919	CLIP-seq
MIRT2174262	hsa-miR-4272	CLIP-seq
MIRT2174263	hsa-miR-4276	CLIP-seq
MIRT2174264	hsa-miR-4316	CLIP-seq
MIRT2174265	hsa-miR-4423-3p	CLIP-seq
MIRT2174266	hsa-miR-4437	CLIP-seq
MIRT2174267	hsa-miR-4455	CLIP-seq
MIRT794399	hsa-miR-4495	CLIP-seq
MIRT2174268	hsa-miR-4539	CLIP-seq
MIRT2174269	hsa-miR-4643	CLIP-seq
MIRT2174270	hsa-miR-466	CLIP-seq
MIRT2174271	hsa-miR-4674	CLIP-seq
MIRT2174272	hsa-miR-4686	CLIP-seq
MIRT2174273	hsa-miR-4694-3p	CLIP-seq
MIRT794406	hsa-miR-4717-3p	CLIP-seq
MIRT2174274	hsa-miR-4724-5p	CLIP-seq
MIRT2174275	hsa-miR-4735-5p	CLIP-seq
MIRT794407	hsa-miR-4760-3p	CLIP-seq
MIRT2174276	hsa-miR-4775	CLIP-seq
MIRT2174277	hsa-miR-4789-3p	CLIP-seq
MIRT2174278	hsa-miR-486-5p	CLIP-seq
MIRT2174279	hsa-miR-487a	CLIP-seq
MIRT2174280	hsa-miR-494	CLIP-seq
MIRT2174281	hsa-miR-496	CLIP-seq
MIRT794411	hsa-miR-543	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT2174282	hsa-miR-548an	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT2174283	hsa-miR-586	CLIP-seq
MIRT2174284	hsa-miR-590-3p	CLIP-seq
MIRT2174285	hsa-miR-607	CLIP-seq
MIRT2174286	hsa-miR-609	CLIP-seq
MIRT2174287	hsa-miR-631	CLIP-seq
MIRT2174288	hsa-miR-646	CLIP-seq
MIRT2174289	hsa-miR-655	CLIP-seq
MIRT794426	hsa-miR-656	CLIP-seq
MIRT2384381	hsa-miR-1224-5p	CLIP-seq
MIRT2384382	hsa-miR-1237	CLIP-seq
MIRT2384383	hsa-miR-129-5p	CLIP-seq
MIRT2174243	hsa-miR-132	CLIP-seq
MIRT794381	hsa-miR-1323	CLIP-seq
MIRT794382	hsa-miR-1343	CLIP-seq
MIRT2384384	hsa-miR-182	CLIP-seq
MIRT2174248	hsa-miR-212	CLIP-seq
MIRT2384385	hsa-miR-3145-5p	CLIP-seq
MIRT2384386	hsa-miR-3176	CLIP-seq
MIRT2384387	hsa-miR-3187-3p	CLIP-seq
MIRT2384388	hsa-miR-331-5p	CLIP-seq
MIRT2174254	hsa-miR-340	CLIP-seq
MIRT2384389	hsa-miR-3613-3p	CLIP-seq
MIRT2174255	hsa-miR-3614-3p	CLIP-seq
MIRT2384390	hsa-miR-3619-3p	CLIP-seq
MIRT2384391	hsa-miR-3646	CLIP-seq
MIRT2384392	hsa-miR-3668	CLIP-seq
MIRT2384393	hsa-miR-380	CLIP-seq
MIRT794393	hsa-miR-3919	CLIP-seq
MIRT2384394	hsa-miR-3922-3p	CLIP-seq
MIRT2384395	hsa-miR-3924	CLIP-seq
MIRT2384396	hsa-miR-4436b-5p	CLIP-seq
MIRT2174266	hsa-miR-4437	CLIP-seq
MIRT794399	hsa-miR-4495	CLIP-seq
MIRT2384397	hsa-miR-4529-5p	CLIP-seq
MIRT2384398	hsa-miR-4535	CLIP-seq
MIRT2174269	hsa-miR-4643	CLIP-seq
MIRT2174270	hsa-miR-466	CLIP-seq
MIRT2174271	hsa-miR-4674	CLIP-seq
MIRT2384399	hsa-miR-4678	CLIP-seq
MIRT794406	hsa-miR-4717-3p	CLIP-seq
MIRT1934457	hsa-miR-4729	CLIP-seq
MIRT2174275	hsa-miR-4735-5p	CLIP-seq
MIRT2384400	hsa-miR-4751	CLIP-seq
MIRT2174276	hsa-miR-4775	CLIP-seq
MIRT2174277	hsa-miR-4789-3p	CLIP-seq
MIRT2174280	hsa-miR-494	CLIP-seq
MIRT794411	hsa-miR-543	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794420	hsa-miR-548o	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT2174284	hsa-miR-590-3p	CLIP-seq
MIRT2174240	hsa-miR-105	CLIP-seq
MIRT2174241	hsa-miR-1185	CLIP-seq
MIRT2174242	hsa-miR-1273d	CLIP-seq
MIRT2426396	hsa-miR-1284	CLIP-seq
MIRT2426397	hsa-miR-1291	CLIP-seq
MIRT2384383	hsa-miR-129-5p	CLIP-seq
MIRT794379	hsa-miR-1297	CLIP-seq
MIRT2174243	hsa-miR-132	CLIP-seq
MIRT794381	hsa-miR-1323	CLIP-seq
MIRT2426398	hsa-miR-146b-3p	CLIP-seq
MIRT2426399	hsa-miR-1910	CLIP-seq
MIRT2426400	hsa-miR-204	CLIP-seq
MIRT2426401	hsa-miR-211	CLIP-seq
MIRT2174248	hsa-miR-212	CLIP-seq
MIRT2426402	hsa-miR-2355-3p	CLIP-seq
MIRT794384	hsa-miR-26a	CLIP-seq
MIRT794385	hsa-miR-26b	CLIP-seq
MIRT2426403	hsa-miR-300	CLIP-seq
MIRT2174249	hsa-miR-3065-5p	CLIP-seq
MIRT2174250	hsa-miR-3074-3p	CLIP-seq
MIRT2174252	hsa-miR-3162-5p	CLIP-seq
MIRT2426404	hsa-miR-323b-5p	CLIP-seq
MIRT2426405	hsa-miR-337-3p	CLIP-seq
MIRT2426406	hsa-miR-338-5p	CLIP-seq
MIRT2426407	hsa-miR-339-5p	CLIP-seq
MIRT1934451	hsa-miR-33a	CLIP-seq
MIRT1934452	hsa-miR-33b	CLIP-seq
MIRT2174254	hsa-miR-340	CLIP-seq
MIRT2384390	hsa-miR-3619-3p	CLIP-seq
MIRT2174257	hsa-miR-3661	CLIP-seq
MIRT2426408	hsa-miR-3662	CLIP-seq
MIRT2174258	hsa-miR-3671	CLIP-seq
MIRT2174260	hsa-miR-3679-5p	CLIP-seq
MIRT2426409	hsa-miR-381	CLIP-seq
MIRT2426410	hsa-miR-411	CLIP-seq
MIRT2426411	hsa-miR-4330	CLIP-seq
MIRT2174265	hsa-miR-4423-3p	CLIP-seq
MIRT794397	hsa-miR-4465	CLIP-seq
MIRT2426412	hsa-miR-4646-3p	CLIP-seq
MIRT2426413	hsa-miR-4666-3p	CLIP-seq
MIRT2174273	hsa-miR-4694-3p	CLIP-seq
MIRT2426414	hsa-miR-4698	CLIP-seq
MIRT2426415	hsa-miR-4725-5p	CLIP-seq
MIRT2426416	hsa-miR-4776-5p	CLIP-seq
MIRT1934458	hsa-miR-485-3p	CLIP-seq
MIRT2174278	hsa-miR-486-5p	CLIP-seq
MIRT2174279	hsa-miR-487a	CLIP-seq
MIRT2426417	hsa-miR-504	CLIP-seq
MIRT794411	hsa-miR-543	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT2174282	hsa-miR-548an	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794420	hsa-miR-548o	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT794423	hsa-miR-556-3p	CLIP-seq
MIRT2426418	hsa-miR-583	CLIP-seq
MIRT2174283	hsa-miR-586	CLIP-seq
MIRT2174285	hsa-miR-607	CLIP-seq
MIRT2174287	hsa-miR-631	CLIP-seq
MIRT794426	hsa-miR-656	CLIP-seq
MIRT2426419	hsa-miR-934	CLIP-seq
MIRT2174241	hsa-miR-1185	CLIP-seq
MIRT794381	hsa-miR-1323	CLIP-seq
MIRT794382	hsa-miR-1343	CLIP-seq
MIRT2174249	hsa-miR-3065-5p	CLIP-seq
MIRT794387	hsa-miR-3128	CLIP-seq
MIRT2174260	hsa-miR-3679-5p	CLIP-seq
MIRT794393	hsa-miR-3919	CLIP-seq
MIRT2435476	hsa-miR-4307	CLIP-seq
MIRT2435477	hsa-miR-4490	CLIP-seq
MIRT794399	hsa-miR-4495	CLIP-seq
MIRT2174269	hsa-miR-4643	CLIP-seq
MIRT2174270	hsa-miR-466	CLIP-seq
MIRT794406	hsa-miR-4717-3p	CLIP-seq
MIRT2426415	hsa-miR-4725-5p	CLIP-seq
MIRT2174277	hsa-miR-4789-3p	CLIP-seq
MIRT2435478	hsa-miR-4796-5p	CLIP-seq
MIRT2426417	hsa-miR-504	CLIP-seq
MIRT794411	hsa-miR-543	CLIP-seq
MIRT794412	hsa-miR-548a-3p	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT2174282	hsa-miR-548an	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794418	hsa-miR-548e	CLIP-seq
MIRT794419	hsa-miR-548f	CLIP-seq
MIRT794420	hsa-miR-548o	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT794423	hsa-miR-556-3p	CLIP-seq
MIRT2174240	hsa-miR-105	CLIP-seq
MIRT2384382	hsa-miR-1237	CLIP-seq
MIRT2174242	hsa-miR-1273d	CLIP-seq
MIRT2477915	hsa-miR-2110	CLIP-seq
MIRT2174250	hsa-miR-3074-3p	CLIP-seq
MIRT2477916	hsa-miR-30a	CLIP-seq
MIRT2477917	hsa-miR-30b	CLIP-seq
MIRT2477918	hsa-miR-30c	CLIP-seq
MIRT2477919	hsa-miR-30d	CLIP-seq
MIRT2477920	hsa-miR-30e	CLIP-seq
MIRT794387	hsa-miR-3128	CLIP-seq
MIRT2477921	hsa-miR-3153	CLIP-seq
MIRT2174252	hsa-miR-3162-5p	CLIP-seq
MIRT2384386	hsa-miR-3176	CLIP-seq
MIRT2384387	hsa-miR-3187-3p	CLIP-seq
MIRT2174255	hsa-miR-3614-3p	CLIP-seq
MIRT2384390	hsa-miR-3619-3p	CLIP-seq
MIRT2426408	hsa-miR-3662	CLIP-seq
MIRT2174258	hsa-miR-3671	CLIP-seq
MIRT2384393	hsa-miR-380	CLIP-seq
MIRT2384394	hsa-miR-3922-3p	CLIP-seq
MIRT2384395	hsa-miR-3924	CLIP-seq
MIRT2477922	hsa-miR-4271	CLIP-seq
MIRT794399	hsa-miR-4495	CLIP-seq
MIRT2477923	hsa-miR-450b-5p	CLIP-seq
MIRT2384397	hsa-miR-4529-5p	CLIP-seq
MIRT2174273	hsa-miR-4694-3p	CLIP-seq
MIRT2477924	hsa-miR-4725-3p	CLIP-seq
MIRT2426416	hsa-miR-4776-5p	CLIP-seq
MIRT2477925	hsa-miR-4790-3p	CLIP-seq
MIRT1934458	hsa-miR-485-3p	CLIP-seq
MIRT2174279	hsa-miR-487a	CLIP-seq
MIRT2477926	hsa-miR-491-5p	CLIP-seq
MIRT2477927	hsa-miR-541	CLIP-seq
MIRT794412	hsa-miR-548a-3p	CLIP-seq
MIRT794413	hsa-miR-548ac	CLIP-seq
MIRT794414	hsa-miR-548ae	CLIP-seq
MIRT794415	hsa-miR-548aj	CLIP-seq
MIRT794416	hsa-miR-548am	CLIP-seq
MIRT794417	hsa-miR-548d-3p	CLIP-seq
MIRT794418	hsa-miR-548e	CLIP-seq
MIRT794419	hsa-miR-548f	CLIP-seq
MIRT794421	hsa-miR-548x	CLIP-seq
MIRT794422	hsa-miR-548z	CLIP-seq
MIRT2174283	hsa-miR-586	CLIP-seq
MIRT2174285	hsa-miR-607	CLIP-seq
MIRT2477928	hsa-miR-654-5p	CLIP-seq
MIRT794426	hsa-miR-656	CLIP-seq
MIRT2384382	hsa-miR-1237	CLIP-seq
MIRT2384383	hsa-miR-129-5p	CLIP-seq
MIRT794381	hsa-miR-1323	CLIP-seq
MIRT2675280	hsa-miR-224	CLIP-seq
MIRT2477916	hsa-miR-30a	CLIP-seq
MIRT2477917	hsa-miR-30b	CLIP-seq
MIRT2477918	hsa-miR-30c	CLIP-seq
MIRT2477919	hsa-miR-30d	CLIP-seq
MIRT2477920	hsa-miR-30e	CLIP-seq
MIRT2384386	hsa-miR-3176	CLIP-seq
MIRT2384387	hsa-miR-3187-3p	CLIP-seq
MIRT2174254	hsa-miR-340	CLIP-seq
MIRT2174255	hsa-miR-3614-3p	CLIP-seq
MIRT2384390	hsa-miR-3619-3p	CLIP-seq
MIRT2426408	hsa-miR-3662	CLIP-seq
MIRT2384393	hsa-miR-380	CLIP-seq
MIRT2384394	hsa-miR-3922-3p	CLIP-seq
MIRT2384395	hsa-miR-3924	CLIP-seq
MIRT2675281	hsa-miR-3927	CLIP-seq
MIRT794399	hsa-miR-4495	CLIP-seq
MIRT2477923	hsa-miR-450b-5p	CLIP-seq
MIRT2675282	hsa-miR-4520b-3p	CLIP-seq
MIRT2675283	hsa-miR-4529-3p	CLIP-seq
MIRT2384397	hsa-miR-4529-5p	CLIP-seq
MIRT2384398	hsa-miR-4535	CLIP-seq
MIRT2675284	hsa-miR-4650-3p	CLIP-seq
MIRT1934457	hsa-miR-4729	CLIP-seq
MIRT2675285	hsa-miR-4773	CLIP-seq
MIRT2426416	hsa-miR-4776-5p	CLIP-seq
MIRT2477925	hsa-miR-4790-3p	CLIP-seq
MIRT1934458	hsa-miR-485-3p	CLIP-seq
MIRT2174280	hsa-miR-494	CLIP-seq
MIRT794420	hsa-miR-548o	CLIP-seq
MIRT2675286	hsa-miR-561	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS	9305890
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	25468996
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007266	Process	Rho protein signal transduction	TAS	9305890
GO:0008270	Function	Zinc ion binding	IEA
GO:0030165	Function	PDZ domain binding	IDA	23209302
GO:0032991	Component	Protein-containing complex	IDA	26780829
GO:0046872	Function	Metal ion binding	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0051058	Process	Negative regulation of small GTPase mediated signal transduction	IBA

Other IDs

• MIM: 610496
• HGNC: 30207
• e!Ensembl: ENSG00000137962

Protein

• UniProt ID: Q52LW3
• Protein name: Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29)
• Protein function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RAS
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00130	C1_1	613 → 660	Phorbol esters/diacylglycerol binding domain (C1 domain)	Domain
  PF00620	RhoGAP	685 → 859	RhoGAP domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Highly expressed in skeletal muscle and heart. Expressed at intermediate level in placenta, liver and pancreas. Weakly expressed in brain, lung and kidney. {ECO:0000269|PubMed:9305890}.
• Sequence:

  MIAHKQKKTKKKRAWASGQLSTDITTSEMGLKSLSSNSIFDPDYIKELVNDIRKFSHMLL
  YLKEAIFSDCFKEVIHIRLEELLRVLKSIMNKHQNLNSVDLQNAAEMLTAKVKAVNFTEV
  NEENKNDLFQEVFSSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENVSVESV
  DSSSEKGNFSPLELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNM
  VKLAEATRTNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRKNEM
  EKQRKEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGL
  AKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTLVFQ
  CDLTLKAVTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNSTEEEKVDG
  NVNKHLNSSQPSGFGPANSLEDVVRLPDSSNKIEEDRCSNSADITGPSFIRSWTFGMFSD
  SESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSETGPNSLGT
  FKKTLMSKAALTHKFRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQ
  KLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQ
  ALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETK
  KNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSK
  NLGVIFGPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQKIFDGSLQPQDVMCSIG
  VVDQGCFPKPLLSPEERDIERSMKSLFFSSKEDIHTSESESKIFERATSFEESERKQNAL
  GKCDACLSDKAQLLLDQEAESASQKIEDGKTPKPLSLKSDRSTNNVERHTPRTKIRPVSL
  PVDRLLLASPPNERNGRNMGNVNLDKFCKNPAFEGVNRKDAATTVCSKFNGFDQQTLQKI
  QDKQYEQNSLTAKTTMIMPSALQEKGVTTSLQISGDHSINATQPSKPYAEPVRSVREASE
  RRSSDSYPLAPVRAPRTLQPQHWTTFYKPHAPIISIRGNEEKPASPSAAVPPGTDHDPHG
  LVVKSMPDPDKASACPGQATGQPKEDSEELGLPDVNPMCQRPRLKRMQQFEDLEGEIPQF
  V

• Sequence length: 1261

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
ARHGAP29-related disorder	Likely pathogenic	rs2524205825	RCV003394312	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Nonsyndromic cleft lip with or without cleft palate	Pathogenic	rs1114167281, rs1114167280, rs1114167282, rs1570497770	RCV000491051 RCV000491498 RCV000491061 RCV000852348	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEFT LIP WITH OR WITHOUT CLEFT PALATE	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cleft palate	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEFT PALATE WITH CLEFT LIP	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEFT PALATE, ISOLATED	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Isolated cleft palate	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OROFACIAL CLEFT	—	ClinGen, Disgenet, Orphanet ClinGen, Disgenet, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
URANOSTAPHYLOSCHISIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Neoplasms	Breast neoplasm	Pubtator	33291460	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	19457610	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	34222474	Associate	★☆☆☆☆ Found in Text Mining only
Cleft Lip	Cleft lip	Pubtator	28662356	Associate	★☆☆☆☆ Found in Text Mining only
Cleft Lip with or without Cleft Palate	Cleft Lip With Or Without Cleft Palate	BEFREE	23008150		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cleft Lip with or without Cleft Palate	Cleft Lip With Or Without Cleft Palate	GENOMICS_ENGLAND_DG	27033726		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cleft Palate	Cleft palate	Pubtator	24738728, 27369588, 33150183	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cleft palate and bilateral cleft lip	Cleft Palate And Bilateral Cleft Lip	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Conductive hearing loss	Hearing Loss	HPO_DG			★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	40053455	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	40053455	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypoplasia of the maxilla	Hypoplasia of the maxilla	HPO_DG			★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	37443829	Stimulate	★☆☆☆☆ Found in Text Mining only
Lymphoma, Lymphocytic, Intermediate	Lymphoma, Lymphocytic, Intermediate	CTD_human_DG	17488656		★☆☆☆☆ Found in Text Mining only
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	Malignant lymphoma, lymphocytic, intermediate differentiation	BEFREE	17488656		★☆☆☆☆ Found in Text Mining only
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	Malignant lymphoma, lymphocytic, intermediate differentiation	CTD_human_DG	17488656		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Malnutrition	Malnutrition	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	17488656		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	17488656, 28538170		★☆☆☆☆ Found in Text Mining only
OROFACIAL CLEFT 1	Orofacial Cleft	BEFREE	25163644		★☆☆☆☆ Found in Text Mining only
Orofacial Cleft 1	Orofacial cleft	Pubtator	33150183	Associate	★☆☆☆☆ Found in Text Mining only
Oropharyngeal Dysphagia	Oropharyngeal Dysphagia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Otofaciocervical Syndrome	Otofaciocervical syndrome	Pubtator	27369588	Associate	★☆☆☆☆ Found in Text Mining only
Recurrent otitis media	Otitis media	HPO_DG			★☆☆☆☆ Found in Text Mining only
Velopharyngeal Insufficiency	Velopharyngeal Insufficiency	HPO_DG			★☆☆☆☆ Found in Text Mining only