ADCY6 (adenylate cyclase 6)

Gene

• Entrez ID: 112
• Gene name: Adenylate cyclase 6
• Gene symbol: ADCY6
• Synonyms (NCBI Gene): AC6, LCCS8
• Chromosome: 12
• Chromosome location: 12q13.12
• Summary: This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay, qRT-PCR	20656788
MIRT016723	hsa-miR-335-5p	Microarray	18185580
MIRT022147	hsa-miR-124-3p	Microarray	18668037
MIRT001991	hsa-miR-96-5p	Sequencing	20371350
MIRT660903	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT660901	hsa-miR-3183	HITS-CLIP	23824327
MIRT660902	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT660900	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT660899	hsa-miR-4287	HITS-CLIP	23824327
MIRT660898	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT660897	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT660896	hsa-miR-5089-3p	HITS-CLIP	23824327
MIRT660895	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT660903	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT660901	hsa-miR-3183	HITS-CLIP	23824327
MIRT660902	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT660900	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT660899	hsa-miR-4287	HITS-CLIP	23824327
MIRT660898	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT660897	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT660896	hsa-miR-5089-3p	HITS-CLIP	23824327
MIRT660895	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT768036	hsa-miR-101	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT768040	hsa-miR-128	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT768042	hsa-miR-1285	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT768044	hsa-miR-1914	CLIP-seq
MIRT768045	hsa-miR-1915	CLIP-seq
MIRT768046	hsa-miR-19a	CLIP-seq
MIRT768047	hsa-miR-19b	CLIP-seq
MIRT768048	hsa-miR-27a	CLIP-seq
MIRT768049	hsa-miR-27b	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768051	hsa-miR-3156-3p	CLIP-seq
MIRT768052	hsa-miR-3162-3p	CLIP-seq
MIRT768053	hsa-miR-3187-5p	CLIP-seq
MIRT768054	hsa-miR-3202	CLIP-seq
MIRT768055	hsa-miR-345	CLIP-seq
MIRT768056	hsa-miR-3945	CLIP-seq
MIRT768057	hsa-miR-4253	CLIP-seq
MIRT768058	hsa-miR-4301	CLIP-seq
MIRT768059	hsa-miR-4316	CLIP-seq
MIRT768060	hsa-miR-4668-5p	CLIP-seq
MIRT768061	hsa-miR-4684-5p	CLIP-seq
MIRT768062	hsa-miR-4726-3p	CLIP-seq
MIRT768063	hsa-miR-4747-5p	CLIP-seq
MIRT768064	hsa-miR-486-3p	CLIP-seq
MIRT768065	hsa-miR-490-3p	CLIP-seq
MIRT768066	hsa-miR-5096	CLIP-seq
MIRT768067	hsa-miR-513a-5p	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT768069	hsa-miR-583	CLIP-seq
MIRT768070	hsa-miR-612	CLIP-seq
MIRT768071	hsa-miR-759	CLIP-seq
MIRT768036	hsa-miR-101	CLIP-seq
MIRT768072	hsa-miR-1197	CLIP-seq
MIRT768073	hsa-miR-1264	CLIP-seq
MIRT768040	hsa-miR-128	CLIP-seq
MIRT768042	hsa-miR-1285	CLIP-seq
MIRT768074	hsa-miR-140-5p	CLIP-seq
MIRT768075	hsa-miR-1909	CLIP-seq
MIRT768045	hsa-miR-1915	CLIP-seq
MIRT768076	hsa-miR-197	CLIP-seq
MIRT768077	hsa-miR-2110	CLIP-seq
MIRT768048	hsa-miR-27a	CLIP-seq
MIRT768049	hsa-miR-27b	CLIP-seq
MIRT768078	hsa-miR-3117-5p	CLIP-seq
MIRT768079	hsa-miR-3126-3p	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768080	hsa-miR-3153	CLIP-seq
MIRT768052	hsa-miR-3162-3p	CLIP-seq
MIRT768081	hsa-miR-3173-3p	CLIP-seq
MIRT768053	hsa-miR-3187-5p	CLIP-seq
MIRT768082	hsa-miR-3199	CLIP-seq
MIRT768054	hsa-miR-3202	CLIP-seq
MIRT768083	hsa-miR-323-3p	CLIP-seq
MIRT768084	hsa-miR-331-3p	CLIP-seq
MIRT768085	hsa-miR-361-3p	CLIP-seq
MIRT768086	hsa-miR-3679-3p	CLIP-seq
MIRT768087	hsa-miR-3921	CLIP-seq
MIRT768088	hsa-miR-3922-5p	CLIP-seq
MIRT768089	hsa-miR-3936	CLIP-seq
MIRT768090	hsa-miR-3938	CLIP-seq
MIRT768056	hsa-miR-3945	CLIP-seq
MIRT768091	hsa-miR-409-5p	CLIP-seq
MIRT768057	hsa-miR-4253	CLIP-seq
MIRT768092	hsa-miR-4271	CLIP-seq
MIRT768093	hsa-miR-4286	CLIP-seq
MIRT768094	hsa-miR-4303	CLIP-seq
MIRT768059	hsa-miR-4316	CLIP-seq
MIRT768095	hsa-miR-4436a	CLIP-seq
MIRT768096	hsa-miR-4438	CLIP-seq
MIRT768097	hsa-miR-4446-5p	CLIP-seq
MIRT768098	hsa-miR-4457	CLIP-seq
MIRT768099	hsa-miR-4475	CLIP-seq
MIRT768100	hsa-miR-4476	CLIP-seq
MIRT768101	hsa-miR-4496	CLIP-seq
MIRT768102	hsa-miR-4515	CLIP-seq
MIRT768103	hsa-miR-4653-5p	CLIP-seq
MIRT768104	hsa-miR-4667-3p	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT768061	hsa-miR-4684-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT768107	hsa-miR-4725-3p	CLIP-seq
MIRT768062	hsa-miR-4726-3p	CLIP-seq
MIRT768108	hsa-miR-4786-3p	CLIP-seq
MIRT768109	hsa-miR-4802-3p	CLIP-seq
MIRT768065	hsa-miR-490-3p	CLIP-seq
MIRT768110	hsa-miR-501-3p	CLIP-seq
MIRT768111	hsa-miR-502-3p	CLIP-seq
MIRT768066	hsa-miR-5096	CLIP-seq
MIRT768067	hsa-miR-513a-5p	CLIP-seq
MIRT768112	hsa-miR-513b	CLIP-seq
MIRT768113	hsa-miR-518d-5p	CLIP-seq
MIRT768114	hsa-miR-519b-5p	CLIP-seq
MIRT768115	hsa-miR-519c-5p	CLIP-seq
MIRT768116	hsa-miR-520c-5p	CLIP-seq
MIRT768117	hsa-miR-526a	CLIP-seq
MIRT768118	hsa-miR-570	CLIP-seq
MIRT768070	hsa-miR-612	CLIP-seq
MIRT768119	hsa-miR-637	CLIP-seq
MIRT768120	hsa-miR-671-5p	CLIP-seq
MIRT768121	hsa-miR-875-3p	CLIP-seq
MIRT1926531	hsa-miR-1205	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT1926532	hsa-miR-125a-3p	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT1926534	hsa-miR-136	CLIP-seq
MIRT1926535	hsa-miR-146b-3p	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT1926537	hsa-miR-204	CLIP-seq
MIRT1926538	hsa-miR-211	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT1926541	hsa-miR-3130-5p	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT1926543	hsa-miR-3154	CLIP-seq
MIRT1926544	hsa-miR-3173-5p	CLIP-seq
MIRT1926545	hsa-miR-3180-5p	CLIP-seq
MIRT1926546	hsa-miR-320e	CLIP-seq
MIRT768055	hsa-miR-345	CLIP-seq
MIRT1926547	hsa-miR-3616-3p	CLIP-seq
MIRT1926548	hsa-miR-3665	CLIP-seq
MIRT1926549	hsa-miR-3688-3p	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT1926552	hsa-miR-4257	CLIP-seq
MIRT1926553	hsa-miR-4261	CLIP-seq
MIRT1926554	hsa-miR-4267	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT1926558	hsa-miR-4436b-3p	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT1926561	hsa-miR-4482	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT1926565	hsa-miR-4689	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT1926569	hsa-miR-4721	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT768109	hsa-miR-4802-3p	CLIP-seq
MIRT1926571	hsa-miR-494	CLIP-seq
MIRT1926572	hsa-miR-515-5p	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT1926574	hsa-miR-543	CLIP-seq
MIRT1926575	hsa-miR-657	CLIP-seq
MIRT1926576	hsa-miR-874	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq
MIRT768036	hsa-miR-101	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT2167516	hsa-miR-1245	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT768040	hsa-miR-128	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT2167517	hsa-miR-1286	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT2167518	hsa-miR-135a	CLIP-seq
MIRT2167519	hsa-miR-135b	CLIP-seq
MIRT2167520	hsa-miR-185	CLIP-seq
MIRT2167521	hsa-miR-1913	CLIP-seq
MIRT768076	hsa-miR-197	CLIP-seq
MIRT1926537	hsa-miR-204	CLIP-seq
MIRT1926538	hsa-miR-211	CLIP-seq
MIRT768077	hsa-miR-2110	CLIP-seq
MIRT768048	hsa-miR-27a	CLIP-seq
MIRT768049	hsa-miR-27b	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT2167522	hsa-miR-3064-5p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT2167524	hsa-miR-3126-5p	CLIP-seq
MIRT2167525	hsa-miR-3127-3p	CLIP-seq
MIRT2167526	hsa-miR-3128	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT2167527	hsa-miR-3144-5p	CLIP-seq
MIRT2167528	hsa-miR-3150b-3p	CLIP-seq
MIRT768080	hsa-miR-3153	CLIP-seq
MIRT2167529	hsa-miR-3155	CLIP-seq
MIRT2167530	hsa-miR-3155b	CLIP-seq
MIRT2167531	hsa-miR-3160-3p	CLIP-seq
MIRT2167532	hsa-miR-3191	CLIP-seq
MIRT2167533	hsa-miR-3201	CLIP-seq
MIRT1926546	hsa-miR-320e	CLIP-seq
MIRT2167534	hsa-miR-324-3p	CLIP-seq
MIRT2167535	hsa-miR-342-5p	CLIP-seq
MIRT2167536	hsa-miR-3609	CLIP-seq
MIRT768085	hsa-miR-361-3p	CLIP-seq
MIRT1926547	hsa-miR-3616-3p	CLIP-seq
MIRT2167537	hsa-miR-3652	CLIP-seq
MIRT2167538	hsa-miR-371b-3p	CLIP-seq
MIRT2167539	hsa-miR-376c	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT768087	hsa-miR-3921	CLIP-seq
MIRT768057	hsa-miR-4253	CLIP-seq
MIRT2167540	hsa-miR-4254	CLIP-seq
MIRT1926552	hsa-miR-4257	CLIP-seq
MIRT2167541	hsa-miR-4266	CLIP-seq
MIRT1926554	hsa-miR-4267	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT768092	hsa-miR-4271	CLIP-seq
MIRT2167542	hsa-miR-4283	CLIP-seq
MIRT2167543	hsa-miR-4290	CLIP-seq
MIRT2167544	hsa-miR-4292	CLIP-seq
MIRT768094	hsa-miR-4303	CLIP-seq
MIRT2167545	hsa-miR-4306	CLIP-seq
MIRT2167546	hsa-miR-4308	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT768059	hsa-miR-4316	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT2167547	hsa-miR-4323	CLIP-seq
MIRT2167548	hsa-miR-4430	CLIP-seq
MIRT1926558	hsa-miR-4436b-3p	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT768098	hsa-miR-4457	CLIP-seq
MIRT2167549	hsa-miR-4489	CLIP-seq
MIRT2167550	hsa-miR-4505	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT2167551	hsa-miR-4643	CLIP-seq
MIRT2167552	hsa-miR-4644	CLIP-seq
MIRT2167553	hsa-miR-4651	CLIP-seq
MIRT2167554	hsa-miR-4652-5p	CLIP-seq
MIRT768103	hsa-miR-4653-5p	CLIP-seq
MIRT2167555	hsa-miR-4664-5p	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT1926565	hsa-miR-4689	CLIP-seq
MIRT2167556	hsa-miR-4695-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT2167557	hsa-miR-4722-5p	CLIP-seq
MIRT768107	hsa-miR-4725-3p	CLIP-seq
MIRT2167558	hsa-miR-4731-5p	CLIP-seq
MIRT2167559	hsa-miR-4779	CLIP-seq
MIRT2167560	hsa-miR-4784	CLIP-seq
MIRT2167561	hsa-miR-4791	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT768109	hsa-miR-4802-3p	CLIP-seq
MIRT2167562	hsa-miR-484	CLIP-seq
MIRT768065	hsa-miR-490-3p	CLIP-seq
MIRT768066	hsa-miR-5096	CLIP-seq
MIRT768067	hsa-miR-513a-5p	CLIP-seq
MIRT2167563	hsa-miR-520g	CLIP-seq
MIRT2167564	hsa-miR-520h	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT2167565	hsa-miR-548ah	CLIP-seq
MIRT2167566	hsa-miR-608	CLIP-seq
MIRT2167567	hsa-miR-670	CLIP-seq
MIRT2167568	hsa-miR-873	CLIP-seq
MIRT768098	hsa-miR-4457	CLIP-seq
MIRT2167557	hsa-miR-4722-5p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT2441918	hsa-miR-4725-5p	CLIP-seq
MIRT2441919	hsa-miR-504	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq
MIRT2443237	hsa-miR-1321	CLIP-seq
MIRT2443238	hsa-miR-4699-5p	CLIP-seq
MIRT2443239	hsa-miR-4739	CLIP-seq
MIRT2443240	hsa-miR-4756-5p	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT2470100	hsa-miR-1231	CLIP-seq
MIRT2470101	hsa-miR-1236	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT768073	hsa-miR-1264	CLIP-seq
MIRT2470102	hsa-miR-1270	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT2470103	hsa-miR-1299	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT2167518	hsa-miR-135a	CLIP-seq
MIRT2167519	hsa-miR-135b	CLIP-seq
MIRT2470104	hsa-miR-150	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT2167520	hsa-miR-185	CLIP-seq
MIRT2470105	hsa-miR-188-3p	CLIP-seq
MIRT2470106	hsa-miR-188-5p	CLIP-seq
MIRT2470107	hsa-miR-224	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT2470108	hsa-miR-3120-5p	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT2167526	hsa-miR-3128	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT2470109	hsa-miR-3144-3p	CLIP-seq
MIRT2167527	hsa-miR-3144-5p	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768051	hsa-miR-3156-3p	CLIP-seq
MIRT768052	hsa-miR-3162-3p	CLIP-seq
MIRT2470110	hsa-miR-3162-5p	CLIP-seq
MIRT2167532	hsa-miR-3191	CLIP-seq
MIRT2167533	hsa-miR-3201	CLIP-seq
MIRT768084	hsa-miR-331-3p	CLIP-seq
MIRT2470111	hsa-miR-337-3p	CLIP-seq
MIRT2470112	hsa-miR-3614-5p	CLIP-seq
MIRT2167537	hsa-miR-3652	CLIP-seq
MIRT2470113	hsa-miR-3661	CLIP-seq
MIRT2470114	hsa-miR-3667-3p	CLIP-seq
MIRT2470115	hsa-miR-3684	CLIP-seq
MIRT2167539	hsa-miR-376c	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT2470116	hsa-miR-3929	CLIP-seq
MIRT2470117	hsa-miR-3941	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT2167543	hsa-miR-4290	CLIP-seq
MIRT768058	hsa-miR-4301	CLIP-seq
MIRT2167545	hsa-miR-4306	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT2470118	hsa-miR-4419b	CLIP-seq
MIRT2167548	hsa-miR-4430	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT2470119	hsa-miR-4474-5p	CLIP-seq
MIRT2470120	hsa-miR-4478	CLIP-seq
MIRT2167550	hsa-miR-4505	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT2470121	hsa-miR-4531	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT2167551	hsa-miR-4643	CLIP-seq
MIRT2167552	hsa-miR-4644	CLIP-seq
MIRT2470122	hsa-miR-4652-3p	CLIP-seq
MIRT2167554	hsa-miR-4652-5p	CLIP-seq
MIRT2470123	hsa-miR-466	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT2470124	hsa-miR-4672	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT2443238	hsa-miR-4699-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT2470125	hsa-miR-4714-5p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT2441918	hsa-miR-4725-5p	CLIP-seq
MIRT2470126	hsa-miR-4731-3p	CLIP-seq
MIRT2167558	hsa-miR-4731-5p	CLIP-seq
MIRT2167561	hsa-miR-4791	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT2470127	hsa-miR-4801	CLIP-seq
MIRT768110	hsa-miR-501-3p	CLIP-seq
MIRT768111	hsa-miR-502-3p	CLIP-seq
MIRT2441919	hsa-miR-504	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT768118	hsa-miR-570	CLIP-seq
MIRT2470128	hsa-miR-602	CLIP-seq
MIRT2470129	hsa-miR-619	CLIP-seq
MIRT2470130	hsa-miR-620	CLIP-seq
MIRT2470131	hsa-miR-631	CLIP-seq
MIRT2470132	hsa-miR-7	CLIP-seq
MIRT768121	hsa-miR-875-3p	CLIP-seq
MIRT2470133	hsa-miR-935	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT2470101	hsa-miR-1236	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT2167518	hsa-miR-135a	CLIP-seq
MIRT2167519	hsa-miR-135b	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT2470105	hsa-miR-188-3p	CLIP-seq
MIRT2470106	hsa-miR-188-5p	CLIP-seq
MIRT2674533	hsa-miR-214	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT2674534	hsa-miR-3120-3p	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT2167526	hsa-miR-3128	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT2167527	hsa-miR-3144-5p	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768051	hsa-miR-3156-3p	CLIP-seq
MIRT2674535	hsa-miR-3166	CLIP-seq
MIRT2167532	hsa-miR-3191	CLIP-seq
MIRT2167533	hsa-miR-3201	CLIP-seq
MIRT2470111	hsa-miR-337-3p	CLIP-seq
MIRT2674536	hsa-miR-3619-5p	CLIP-seq
MIRT2167537	hsa-miR-3652	CLIP-seq
MIRT2470113	hsa-miR-3661	CLIP-seq
MIRT2470114	hsa-miR-3667-3p	CLIP-seq
MIRT2470115	hsa-miR-3684	CLIP-seq
MIRT2167539	hsa-miR-376c	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT2470116	hsa-miR-3929	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT2167543	hsa-miR-4290	CLIP-seq
MIRT2674537	hsa-miR-4291	CLIP-seq
MIRT768058	hsa-miR-4301	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT2470118	hsa-miR-4419b	CLIP-seq
MIRT2167548	hsa-miR-4430	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT2470119	hsa-miR-4474-5p	CLIP-seq
MIRT2470120	hsa-miR-4478	CLIP-seq
MIRT2167550	hsa-miR-4505	CLIP-seq
MIRT2674538	hsa-miR-451b	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT2167551	hsa-miR-4643	CLIP-seq
MIRT2167554	hsa-miR-4652-5p	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT2470125	hsa-miR-4714-5p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT2441918	hsa-miR-4725-5p	CLIP-seq
MIRT2167558	hsa-miR-4731-5p	CLIP-seq
MIRT2167561	hsa-miR-4791	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT768110	hsa-miR-501-3p	CLIP-seq
MIRT768111	hsa-miR-502-3p	CLIP-seq
MIRT2441919	hsa-miR-504	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT768118	hsa-miR-570	CLIP-seq
MIRT2470129	hsa-miR-619	CLIP-seq
MIRT2470131	hsa-miR-631	CLIP-seq
MIRT2674539	hsa-miR-761	CLIP-seq
MIRT768121	hsa-miR-875-3p	CLIP-seq
MIRT2674540	hsa-miR-922	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003091	Process	Renal water homeostasis	ISS
GO:0004016	Function	Adenylate cyclase activity	IBA
GO:0004016	Function	Adenylate cyclase activity	IDA	17916776, 18403039, 23842570
GO:0004016	Function	Adenylate cyclase activity	IEA
GO:0005080	Function	Protein kinase C binding	IDA	17081159
GO:0005515	Function	Protein binding	IPI	17081159
GO:0005524	Function	ATP binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0005929	Component	Cilium	IEA
GO:0006171	Process	CAMP biosynthetic process	IBA
GO:0006171	Process	CAMP biosynthetic process	IDA	17916776, 18403039
GO:0006171	Process	CAMP biosynthetic process	IEA
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	17110384, 17916776
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISS
GO:0007191	Process	Adenylate cyclase-activating dopamine receptor signaling pathway	IDA	18403039
GO:0007192	Process	Adenylate cyclase-activating serotonin receptor signaling pathway	IDA	17110384
GO:0007193	Process	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISS
GO:0007198	Process	Adenylate cyclase-inhibiting serotonin receptor signaling pathway	ISS
GO:0009190	Process	Cyclic nucleotide biosynthetic process	IEA
GO:0010977	Process	Negative regulation of neuron projection development	ISS
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016829	Function	Lyase activity	IEA
GO:0016849	Function	Phosphorus-oxygen lyase activity	IEA
GO:0019901	Function	Protein kinase binding	ISS
GO:0032420	Component	Stereocilium	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0035811	Process	Negative regulation of urine volume	ISS
GO:0042995	Component	Cell projection	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0071380	Process	Cellular response to prostaglandin E stimulus	IDA	18403039
GO:0071870	Process	Cellular response to catecholamine stimulus	IDA	18403039
GO:0097746	Process	Blood vessel diameter maintenance	IMP	17916776
GO:1904117	Process	Cellular response to vasopressin	ISS
GO:1904322	Process	Cellular response to forskolin	IDA	17916776

Other IDs

• MIM: 600294
• HGNC: 237
• e!Ensembl: ENSG00000174233

Protein

• UniProt ID: O43306
• Protein name: Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)
• Protein function: Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17110384, PubMed:17916776). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth musc
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF16214	AC_N	11 → 368	Adenylyl cyclase N-terminal extracellular and transmembrane region	Family
  PF00211	Guanylate_cyc	370 → 553	Adenylate and Guanylate cyclase catalytic domain	Domain
  PF06327	DUF1053	580 → 669	Domain of Unknown Function (DUF1053)	Family
  PF00211	Guanylate_cyc	970 → 1164	Adenylate and Guanylate cyclase catalytic domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in peripheral blood mononuclear leukocytes (at protein level) (PubMed:17916776). Detected in thyroid (PubMed:10978539). {ECO:0000269|PubMed:10978539}.
• Sequence:

  MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGP
  PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGRSCWR
  RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAY
  VALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLW
  CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN
  VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT
  KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC
  LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV
  HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA
  YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR
  QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKK
  YSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSC
  GSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRSCAARMLNLT
  PADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLA
  MIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV
  ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF
  LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS
  EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN
  FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG
  YQLECRGVVKVKGKGEMTTYFLNGGPSS

• Sequence length: 1168

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Lethal congenital contracture syndrome 8	Pathogenic	rs786204798, rs1941705738, rs1941551290	RCV000169693 RCV001290106 RCV001290107	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ADCY6-related disorder	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DEFORMITY OF CLAVICLE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DEFORMITY OF ELBOW	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DEFORMITY OF FOREARM	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DEFORMITY OF SCAPULA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DEFORMITY OF WRIST	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISLOCATION OF ELBOW	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISLOCATION OF GLENOHUMERAL JOINT	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIVERTICULITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LETHAL CONGENITAL CONTRACTURE SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Anemia Sickle Cell	Sickle cell anemia	Pubtator	18324973	Associate	★☆☆☆☆ Found in Text Mining only
Anemia, Sickle Cell	Anemia	BEFREE	18324973, 27067484		★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety disorder	Pubtator	28969474	Associate	★☆☆☆☆ Found in Text Mining only
Arrhythmias Cardiac	Cardiac arrhythmias	Pubtator	27437887	Associate	★☆☆☆☆ Found in Text Mining only
Arthrogryposis	Arthrogryposis multiplex congenita	BEFREE	24319099		★☆☆☆☆ Found in Text Mining only
Arthrogryposis	Arthrogryposis	Pubtator	33820833	Associate	★☆☆☆☆ Found in Text Mining only
Arthrogryposis	Arthrogryposis multiplex congenita	HPO_DG			★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	Pubtator	32108986	Associate	★☆☆☆☆ Found in Text Mining only
Bone Diseases Developmental	Bone disease	Pubtator	33820833	Associate	★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	27437887		★☆☆☆☆ Found in Text Mining only
Cystic kidney	Cystic Kidney Disease	BEFREE	22641646		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	27810435		★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	LHGDN	17007567		★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	27437887		★☆☆☆☆ Found in Text Mining only
Hypomyelination neuropathy-arthrogryposis syndrome	Hypomyelination Neuropathy-Arthrogryposis Syndrome	Orphanet			★☆☆☆☆ Found in Text Mining only
Left Ventricular Hypertrophy	Left Ventricular Hypertrophy	LHGDN	14871025		★☆☆☆☆ Found in Text Mining only
LETHAL CONGENITAL CONTRACTURE SYNDROME 8	Lethal Congenital Contracture Syndrome	GENOMICS_ENGLAND_DG	24319099		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
LETHAL CONGENITAL CONTRACTURE SYNDROME 8	Lethal Congenital Contracture Syndrome	UNIPROT_DG	24319099		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
LETHAL CONGENITAL CONTRACTURE SYNDROME 8	Lethal Congenital Contracture Syndrome	CLINVAR_DG	26257172		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
LETHAL CONGENITAL CONTRACTURE SYNDROME 8	Lethal Congenital Contracture Syndrome	BEFREE	31846058		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
LETHAL CONGENITAL CONTRACTURE SYNDROME 8	Lethal Congenital Contracture Syndrome	CTD_human_DG			★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Metabolic Diseases	Metabolic syndrome	Pubtator	30926763	Associate	★☆☆☆☆ Found in Text Mining only
Nephrogenic Diabetes Insipidus	Nephrogenic Diabetes Insipidus	BEFREE	28405619		★☆☆☆☆ Found in Text Mining only
Oropharyngeal Dysphagia	Oropharyngeal Dysphagia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	BEFREE	30413613		★☆☆☆☆ Found in Text Mining only
Polycystic Kidney Autosomal Dominant	Polycystic kidney disease	Pubtator	22952279	Associate	★☆☆☆☆ Found in Text Mining only
Polycystic Kidney, Autosomal Dominant	Polycystic kidney disease	BEFREE	24994926		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic ovary syndrome	Pubtator	33622336	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Nodule	Thyroid Nodule	BEFREE	12782409		★☆☆☆☆ Found in Text Mining only