Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	100124696
Gene name	-
Gene symbol	TEC
Synonyms (NCBI Gene)	-
Chromosome	19
Chromosome location	19q13.2
Summary	The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surfac

92 Show/Hide all (92)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047018	hsa-miR-204-5p	CLASH	23622248
MIRT1417581	hsa-miR-1236	CLIP-seq
MIRT1417582	hsa-miR-1254	CLIP-seq
MIRT1417583	hsa-miR-1255a	CLIP-seq
MIRT1417584	hsa-miR-1255b	CLIP-seq
MIRT1417585	hsa-miR-128	CLIP-seq
MIRT1417586	hsa-miR-2355-5p	CLIP-seq
MIRT1417587	hsa-miR-30a	CLIP-seq
MIRT1417588	hsa-miR-30b	CLIP-seq
MIRT1417589	hsa-miR-30c	CLIP-seq
MIRT1417590	hsa-miR-30d	CLIP-seq
MIRT1417591	hsa-miR-30e	CLIP-seq
MIRT1417592	hsa-miR-3116	CLIP-seq
MIRT1417593	hsa-miR-3136-5p	CLIP-seq
MIRT1417594	hsa-miR-3140-5p	CLIP-seq
MIRT1417595	hsa-miR-324-5p	CLIP-seq
MIRT1417596	hsa-miR-326	CLIP-seq
MIRT1417597	hsa-miR-329	CLIP-seq
MIRT1417598	hsa-miR-330-5p	CLIP-seq
MIRT1417599	hsa-miR-362-3p	CLIP-seq
MIRT1417600	hsa-miR-3926	CLIP-seq
MIRT1417601	hsa-miR-3941	CLIP-seq
MIRT1417602	hsa-miR-4269	CLIP-seq
MIRT1417603	hsa-miR-4283	CLIP-seq
MIRT1417604	hsa-miR-4292	CLIP-seq
MIRT1417605	hsa-miR-4305	CLIP-seq
MIRT1417606	hsa-miR-4439	CLIP-seq
MIRT1417607	hsa-miR-4489	CLIP-seq
MIRT1417608	hsa-miR-4490	CLIP-seq
MIRT1417609	hsa-miR-4513	CLIP-seq
MIRT1417610	hsa-miR-4514	CLIP-seq
MIRT1417611	hsa-miR-4659a-3p	CLIP-seq
MIRT1417612	hsa-miR-4659b-3p	CLIP-seq
MIRT1417613	hsa-miR-4692	CLIP-seq
MIRT1417614	hsa-miR-4742-5p	CLIP-seq
MIRT1417615	hsa-miR-4753-3p	CLIP-seq
MIRT1417616	hsa-miR-4782-5p	CLIP-seq
MIRT1417617	hsa-miR-4790-3p	CLIP-seq
MIRT1417618	hsa-miR-515-3p	CLIP-seq
MIRT1417619	hsa-miR-519e	CLIP-seq
MIRT1417620	hsa-miR-548s	CLIP-seq
MIRT1417621	hsa-miR-550a	CLIP-seq
MIRT1417622	hsa-miR-582-5p	CLIP-seq
MIRT1417623	hsa-miR-593	CLIP-seq
MIRT1417624	hsa-miR-603	CLIP-seq
MIRT1417625	hsa-miR-642b	CLIP-seq
MIRT1417626	hsa-miR-661	CLIP-seq
MIRT1417627	hsa-miR-668	CLIP-seq
MIRT1417628	hsa-miR-942	CLIP-seq
MIRT1417581	hsa-miR-1236	CLIP-seq
MIRT2125391	hsa-miR-3064-5p	CLIP-seq
MIRT2125392	hsa-miR-3605-3p	CLIP-seq
MIRT1417602	hsa-miR-4269	CLIP-seq
MIRT1417610	hsa-miR-4514	CLIP-seq
MIRT1417611	hsa-miR-4659a-3p	CLIP-seq
MIRT1417612	hsa-miR-4659b-3p	CLIP-seq
MIRT1417613	hsa-miR-4692	CLIP-seq
MIRT1417614	hsa-miR-4742-5p	CLIP-seq
MIRT1417615	hsa-miR-4753-3p	CLIP-seq
MIRT2125393	hsa-miR-4768-5p	CLIP-seq
MIRT2125394	hsa-miR-604	CLIP-seq
MIRT2125395	hsa-miR-647	CLIP-seq
MIRT1417628	hsa-miR-942	CLIP-seq
MIRT1417583	hsa-miR-1255a	CLIP-seq
MIRT1417584	hsa-miR-1255b	CLIP-seq
MIRT2347589	hsa-miR-186	CLIP-seq
MIRT2347590	hsa-miR-3120-3p	CLIP-seq
MIRT1417593	hsa-miR-3136-5p	CLIP-seq
MIRT2347591	hsa-miR-3184	CLIP-seq
MIRT1417596	hsa-miR-326	CLIP-seq
MIRT1417598	hsa-miR-330-5p	CLIP-seq
MIRT2347592	hsa-miR-338-5p	CLIP-seq
MIRT2347593	hsa-miR-423-5p	CLIP-seq
MIRT1417606	hsa-miR-4439	CLIP-seq
MIRT1417609	hsa-miR-4513	CLIP-seq
MIRT2347594	hsa-miR-4688	CLIP-seq
MIRT1417616	hsa-miR-4782-5p	CLIP-seq
MIRT1417622	hsa-miR-582-5p	CLIP-seq
MIRT1417623	hsa-miR-593	CLIP-seq
MIRT1417594	hsa-miR-3140-5p	CLIP-seq
MIRT2395637	hsa-miR-3179	CLIP-seq
MIRT2395638	hsa-miR-4747-5p	CLIP-seq
MIRT2395639	hsa-miR-524-3p	CLIP-seq
MIRT2395640	hsa-miR-525-3p	CLIP-seq
MIRT2640558	hsa-miR-3915	CLIP-seq
MIRT2640559	hsa-miR-3928	CLIP-seq
MIRT2640560	hsa-miR-4765	CLIP-seq
MIRT1417618	hsa-miR-515-3p	CLIP-seq
MIRT1417619	hsa-miR-519e	CLIP-seq
MIRT2640561	hsa-miR-544b	CLIP-seq
MIRT1417621	hsa-miR-550a	CLIP-seq
MIRT1417627	hsa-miR-668	CLIP-seq

MIM	HGNC	e!Ensembl
227050	N/A	N/A

Interactions View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal. Show/Hide Unknown Diseases (7)
Clear cell carcinoma of kidney	Uncertain significance	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Uncertain significance	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOSITIS	—	GWAS catalog	36580032	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	38757301	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	24390342, 30423114, 36333501	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	40069456	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining Show/Hide Text Mining Associations (35)
Age related macular degeneration	Age-related macular degeneration	BEFREE	28601519		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia	Anemia	BEFREE	9260752		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia, Diamond-Blackfan	Anemia	BEFREE	12358933		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Gouty	Gouty arthritis	Pubtator	18512796	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Chronic Hepatitis	Autoimmune hepatitis	BEFREE	23867620		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	23867620, 27173733		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	19332043, 25480315, 29541388		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bruton type agammaglobulinemia	Bruton type agammaglobulinemia	Pubtator	10688822, 9280283, 9446655	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	BEFREE	10359536, 12049818, 22581839		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chondrosarcoma Extraskeletal Myxoid	Extraskeletal myxoid chondrosarcoma	Pubtator	12598313, 17302560	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	22524658, 23356224		★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	21437271	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Desmoplastic Small Round Cell Tumor	Desmoplastic Tumor	BEFREE	9344317		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	36736734	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	36736734	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelioma	Epithelioma	BEFREE	19875502		★★★★★ ★☆☆☆☆ Found in Text Mining only
Extraskeletal Myxoid Chondrosarcoma	Extraskeletal Myxoid Chondrosarcoma	BEFREE	10537274, 11156374, 12049818, 15188455, 22804337		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	31471313		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glycogen storage disease type II	Glycogen Storage Disease	BEFREE	28601519		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gout	Gout	Pubtator	18512796	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Idiopathic pulmonary arterial hypertension	Pulmonary arterial hypertension	BEFREE	30846469		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	2284097		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	19332043, 25480315, 29541388		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28343126		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myasthenia Gravis	Myasthenia Gravis	BEFREE	9973484		★★★★★ ★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	7934162		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12049818, 12598313, 29158813		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	33213062	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Post-Traumatic Stress Disorder	Stress Disorder	BEFREE	30735853, 31760337		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	22524658, 23356224		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	GWASDB_DG	24390342		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Rheumatoid Arthritis	Rheumatoid arthritis	GWASCAT_DG	24390342		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	28607508		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Soft Tissue Neoplasms	Soft Tissue Neoplasms	BEFREE	9344317		★★★★★ ★☆☆☆☆ Found in Text Mining only
Thymoma	Thymoma	BEFREE	9973484		★★★★★ ★☆☆☆☆ Found in Text Mining only

TEC (-)

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