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platelet-type bleeding disorder 16
platelet-type bleeding disorder 16
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
platelet-type bleeding disorder 16
ITGA2B
Causal
—
ClinGen
Rap1 signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Platelet activation
Neutrophil extracellular trap formation
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Cytoskeleton in muscle cells
Human papillomavirus infection
Pathways in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy
Fluid shear stress and atherosclerosis
Platelet degranulation
Integrin cell surface interactions
ECM proteoglycans
Integrin signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
Signal transduction by L1
MAP2K and MAPK activation
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Signaling downstream of RAS mutants
+27 more
platelet-type bleeding disorder 16
ITGB3
Causal
—
ClinGen
Virion - Herpesvirus
Rap1 signaling pathway
Hormone signaling
Phagosome
Efferocytosis
PI3K-Akt signaling pathway
Osteoclast differentiation
Focal adhesion
ECM-receptor interaction
Platelet activation
Neutrophil extracellular trap formation
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Cytoskeleton in muscle cells
Thyroid hormone signaling pathway
Human cytomegalovirus infection
Human papillomavirus infection
Herpes simplex virus 1 infection
Proteoglycans in cancer
MicroRNAs in cancer
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy
Fluid shear stress and atherosclerosis
Platelet degranulation
Elastic fibre formation
PECAM1 interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
Integrin signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
VEGFA-VEGFR2 Pathway
Signal transduction by L1
MAP2K and MAPK activation
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Signaling downstream of RAS mutants
+39 more
All
2
Causal
2
Unknown
0
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
2
Related Diseases
Diseases that share the most curated genes with platelet-type bleeding disorder 16.
5
View disease cluster →
Glanzmann thrombasthenia
2 shared genes
ITGB3, ITGA2B
Related via 2 shared genes including ITGB3, ITGA2B.
Thrombasthenia
2 shared genes
ITGB3, ITGA2B
Related via 2 shared genes including ITGB3, ITGA2B.
Carotid artery thrombosis
2 shared genes
ITGB3, ITGA2B
Related via 2 shared genes including ITGB3, ITGA2B.
Hyper-immunoglobulin e syndrome
1 shared gene
ITGB3
Related via 1 shared gene including ITGB3.
Macrothrombocytopenia
2 shared genes
ITGB3, ITGA2B
Related via 2 shared genes including ITGB3, ITGA2B.
1
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