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lissencephaly spectrum disorders
lissencephaly spectrum disorders
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
lissencephaly spectrum disorders
APC2
Unknown
—
ClinGen
Wnt signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Cushing syndrome
Alzheimer disease
Pathways of neurodegeneration - multiple diseases
Human papillomavirus infection
Pathways in cancer
MicroRNAs in cancer
Colorectal cancer
Endometrial cancer
Basal cell carcinoma
Breast cancer
Hepatocellular carcinoma
Gastric cancer
+13 more
DCX
Unknown
—
ClinGen
—
TUBG1
Unknown
—
ClinGen
Motor proteins
Human papillomavirus infection
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
+6 more
All
3
Causal
0
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
3
Related Diseases
Diseases that share the most curated genes with lissencephaly spectrum disorders.
5
View disease cluster →
Lissencephaly, x-linked
1 shared gene
DCX
Related via 1 shared gene including DCX.
15q11.2 microdeletion syndrome
1 shared gene
TUBG1
Related via 1 shared gene including TUBG1.
Sotos syndrome
1 shared gene
APC2
Related via 1 shared gene including APC2.
Cortical dysplasia with other brain malformations
2 shared genes
TUBG1, APC2
Related via 2 shared genes including TUBG1, APC2.
Complex cortical dysplasia with other brain malformations
1 shared gene
TUBG1
Related via 1 shared gene including TUBG1.
1
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