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interstitial lung disease 2
interstitial lung disease 2
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Interstitial lung disease 2
SFTPA2
Causal
26792177
21506748
19100526
32855221
21506741
ClinGen
Phagosome
Pertussis
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Signal regulatory protein family interactions
Surfactant metabolism
Regulation of TLR by endogenous ligand
Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF)
Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)
Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
+7 more
All
1
Causal
1
Unknown
0
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
1
Related Diseases
Diseases that share the most curated genes with interstitial lung disease 2.
2
View disease cluster →
Interstitial lung disease
1 shared gene
SFTPA2
Related via 1 shared gene including SFTPA2.
Idiopathic pulmonary fibrosis
1 shared gene
SFTPA2
Related via 1 shared gene including SFTPA2.
1
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