Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
uterine carcinosarcoma	MONDO_0006485	CDKN2A	Unknown	33021035	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CHD4	Unknown	33021035 28940304	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CHEK2	Unknown	28481359	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CIC	Unknown	33021035	Open Targets	Spinocerebellar ataxia
		CIITA	Unknown	33021035	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CLIP1	Unknown	33021035	Open Targets	mTOR signaling pathway Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		CLTC	Unknown	33021035	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CNBD1	Unknown	33021035	Open Targets	—
		CNOT3	Unknown	33021035	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		COL1A1	Unknown	33021035	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL3A1	Unknown	33021035	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CREB3L2	Unknown	33021035	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway +32 more
		CREBBP	Unknown	28481359 28940304	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRTC1	Unknown	33021035	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSMD3	Unknown	33021035	Open Targets	—
		CTCF	Unknown	33021035 28481359	Open Targets	—
		CTNNA2	Unknown	28940304	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNNB1	Unknown	25233892 39040939 21168197 22653804	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND2	Unknown	33021035	Open Targets	Wnt signaling pathway
		DCAF12L2	Unknown	28940304	Open Targets	—
		DCC	Unknown	33021035	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDB2	Unknown	33021035	Open Targets	Nucleotide excision repair p53 signaling pathway Ubiquitin mediated proteolysis +23 more
		DDX10	Unknown	33021035	Open Targets	—
		DICER1	Unknown	28940304 33503190 33021035 26428316 25233892 28481359	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		DNMT3A	Unknown	33503190 33021035 28481359	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		DROSHA	Unknown	33021035	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis
		EBF1	Unknown	33021035	Open Targets	—
		EGFR	Unknown	33021035 25233892	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EIF3E	Unknown	33021035	Open Targets	Hepatitis C L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation +4 more
		EML4	Unknown	33021035	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer +1 more
		EP300	Unknown	33021035 28481359	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		EPHA3	Unknown	28481359	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		ERBB3	Unknown	28481359 30266945	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERBB4	Unknown	33503190	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERCC2	Unknown	28481359	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERG	Unknown	33021035	Open Targets	Transcriptional misregulation in cancer Prostate cancer
		ESR1	Unknown	28481359	Open Targets	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		FAM135B	Unknown	28940304	Open Targets	—
		FAT3	Unknown	28940304	Open Targets	—
		FAT4	Unknown	28940304	Open Targets	Hippo signaling pathway - multiple species
		FBLN2	Unknown	33021035	Open Targets	Cytoskeleton in muscle cells Molecules associated with elastic fibres
		FBXO11	Unknown	25233892 28481359 28940304	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	33021035 25233892 28481359 28940304	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FGFR2	Unknown	26373574 33503190 33021035 28481359 30266945	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FLT4	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FOXL2	Unknown	33021035	Open Targets	SUMOylation of transcription factors
		FOXP1	Unknown	28481359	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FUBP1	Unknown	33021035	Open Targets	—
		GOLGA5	Unknown	33021035	Open Targets	Intra-Golgi traffic
		GPC3	Unknown	28940304	Open Targets	Proteoglycans in cancer A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis +9 more

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Uterine carcinosarcoma

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