Subtype of: Thyroid neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
Thyroid Gland Oncocytic Follicular Carcinoma	EFO_1000592	ABL2	Unknown	30107175	Open Targets	ErbB signaling pathway Ras signaling pathway Chemical carcinogenesis - reactive oxygen species +2 more
		ACSL3	Unknown	30107175	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +8 more
		ACSL6	Unknown	30107175	Open Targets	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways +7 more
		AFDN	Unknown	25625803	Open Targets	Ras signaling pathway Rap1 signaling pathway cAMP signaling pathway +4 more
		AKAP9	Unknown	30107175 23543667	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		AKT1	Unknown	19487299	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		ALK	Unknown	24475247	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		ANK1	Unknown	30107175	Open Targets	Proteoglycans in cancer Interaction between L1 and Ankyrins Neurofascin interactions +1 more
		ARHGAP35	Unknown	30107175	Open Targets	Focal adhesion Platelet activation Leukocyte transendothelial migration +4 more
		ARHGAP5	Unknown	25625803	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		ARID1B	Unknown	25625803	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ASPM	Unknown	30107175	Open Targets	—
		ATM	Unknown	30107175 34680332	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATP2B3	Unknown	25625803 30107175	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
		AXIN2	Unknown	30107175	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BARD1	Unknown	30107175	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BCORL1	Unknown	30107175	Open Targets	Polycomb repressive complex
		BRAF	Unknown	22105775 30107175 21498916 23543667	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	25625803	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	30107175	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BTK	Unknown	30107175	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		CACNA1D	Unknown	25625803 30107175	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CAMTA1	Unknown	30107175	Open Targets	—
		CARD11	Unknown	30107175	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CBFA2T3	Unknown	30107175	Open Targets	—
		CBLB	Unknown	30107175	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CCDC6	Unknown	16595592 25111330 14668719 21498916 11788677 20703476	Open Targets	Pathways in cancer Thyroid cancer
		CD74	Unknown	30107175	Open Targets	Antigen processing and presentation Tuberculosis Herpes simplex virus 1 infection +2 more
		CDH11	Unknown	30107175	Open Targets	Adherens junctions interactions
		CDKN1A	Unknown	30107175	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CHD2	Unknown	30107175	Open Targets	—
		CIC	Unknown	30107175	Open Targets	Spinocerebellar ataxia
		CIITA	Unknown	30107175	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CNTRL	Unknown	30107175	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		COL1A1	Unknown	30107175	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL3A1	Unknown	30107175	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CPEB3	Unknown	30107175	Open Targets	Oocyte meiosis Progesterone-mediated oocyte maturation
		CREBBP	Unknown	30107175	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CSF1R	Unknown	30107175	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CTNNA2	Unknown	30107175	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CUL3	Unknown	30107175	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		DAXX	Unknown	25625803 30107175	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more
		DCAF12L2	Unknown	30107175	Open Targets	—
		DCC	Unknown	25625803 30107175	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDX3X	Unknown	30107175	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		DDX6	Unknown	25625803	Open Targets	RNA degradation mRNA decay by 5' to 3' exoribonuclease
		DROSHA	Unknown	30107175	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis
		EBF1	Unknown	30107175	Open Targets	—
		EIF1AX	Unknown	30107175	Open Targets	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits +3 more
		ERBB3	Unknown	30107175	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more

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Thyroid gland oncocytic follicular carcinoma

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