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Spasticity
Spasticity
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Include the contents of this disease's 1 subtype
in the table below
Show the subtype
Spasticity with hyperglycinemia
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Spasticity
HP:0001257
FBXO31
Unknown
24623383
32989326
41640354
33675180
35019165
Open Targets
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
LIG3
Unknown
33855352
Open Targets
Base excision repair
Resolution of AP sites via the single-nucleotide replacement pathway
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
HDR through MMEJ (alt-NHEJ)
Gap-filling DNA repair synthesis and ligation in GG-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
+3 more
MED27
Unknown
33443317
Open Targets
Thyroid hormone signaling pathway
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
+1 more
TAF1C
Unknown
32779182
Open Targets
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
+1 more
All
4
Causal
0
Unknown
4
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
4
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Diseases that share the most curated genes with Spasticity.
5
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Neurodevelopmental disorder with spasticity, cataracts, and cerebellar hypoplasia
1 shared gene
MED27
Related via 1 shared gene including MED27.
Ectopic thyroid tissue
1 shared gene
FBXO31
Related via 1 shared gene including FBXO31.
Repetitive behaviours
1 shared gene
LIG3
Related via 1 shared gene including LIG3.
Axial hypotonia
1 shared gene
MED27
Related via 1 shared gene including MED27.
Neurogenic bladder
1 shared gene
LIG3
Related via 1 shared gene including LIG3.
1
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