Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
SKIN NEOPLASMS	MESH:D012878	EPHX1	Unknown	26295053	CTD	Metabolism of xenobiotics by cytochrome P450 Bile secretion Chemical carcinogenesis - DNA adducts +3 more
		ERBB4	Unknown	19718025	CTD	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERCC2	Unknown	17050553	CTD	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		FLT1	Unknown	19718025	CTD	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +8 more
		GJA1	Unknown	7586191	CTD	Gap junction Arrhythmogenic right ventricular cardiomyopathy Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane +4 more
		GJB2	Unknown	7586191	CTD	Transport of connexons to the plasma membrane
		GJB5	Unknown	7586191	CTD	Gap junction assembly
		GLI2	Unknown	10700170	CTD	Hedgehog signaling pathway Hippo signaling pathway Pathways in cancer +4 more
		GSTT1	Unknown	26295053	CTD	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +10 more
		GYPA	Unknown	17029826	CTD	Hematopoietic cell lineage Malaria Cell surface interactions at the vascular wall
		HCAR2	Unknown	21655214	CTD	cAMP signaling pathway Hydroxycarboxylic acid-binding receptors Class A/1 (Rhodopsin-like receptors) +1 more
		HCAR3	Unknown	21655214	CTD	cAMP signaling pathway Hydroxycarboxylic acid-binding receptors G alpha (i) signalling events
		HIF1A	Unknown	19276359	CTD	HIF-1 signaling pathway Mitophagy - animal Autophagy - animal +19 more
		HRAS	Unknown	15958052 18758463 24898257 26558449 8330346 8508502 9766437	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		IGF1	Unknown	24353828	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +35 more
		IGF1R	Unknown	10365914	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +31 more
		IL1A	Unknown	8435107	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction Necroptosis +24 more
		IVL	Unknown	18572023	CTD	Formation of the cornified envelope
		KRT1	Unknown	18572023	CTD	Neutrophil degranulation Keratinization Formation of the cornified envelope
		KRT10	Unknown	18572023	CTD	Estrogen signaling pathway Staphylococcus aureus infection Keratinization +1 more
		KRT17	Unknown	26168014	CTD	Estrogen signaling pathway Staphylococcus aureus infection Keratinization +1 more
		LORICRIN	Unknown	18572023	CTD	Formation of the cornified envelope
		MMP9	Unknown	18572023	CTD	Endocrine resistance IL-17 signaling pathway TNF signaling pathway +22 more
		NFE2L2	Unknown	18572023	CTD	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NOTCH1	Unknown	27923803	CTD	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +20 more
		NOTCH2	Unknown	27923803	CTD	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NOTCH3	Unknown	27923803	CTD	Endocrine resistance Notch signaling pathway Apelin signaling pathway +13 more
		NOTCH4	Unknown	27923803	CTD	Endocrine resistance Notch signaling pathway Thyroid hormone signaling pathway +11 more
		NPPA	Unknown	18004088	CTD	cGMP-PKG signaling pathway cAMP signaling pathway HIF-1 signaling pathway +11 more
		NPPC	Unknown	37352108	CTD	cGMP-PKG signaling pathway Hormone signaling Vascular smooth muscle contraction +2 more
		ODC1	Unknown	2591024 7653998	CTD	Arginine and proline metabolism Glutathione metabolism Metabolic pathways +3 more
		POT1	Unknown	24686849	CTD	Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Packaging Of Telomere Ends +2 more
		PPARD	Unknown	19748995 21159610	CTD	PPAR signaling pathway Efferocytosis Wnt signaling pathway +6 more
		PTCH1	Unknown	9581815	CTD	cAMP signaling pathway Hedgehog signaling pathway Axon guidance +7 more
		PTGS2	Unknown	17499752 19748995 21159610	CTD	Arachidonic acid metabolism Metabolic pathways NF-kappa B signaling pathway +29 more
		PTK2B	Unknown	19718025	CTD	Calcium signaling pathway Chemokine signaling pathway Phospholipase D signaling pathway +10 more
		RELA	Unknown	23069812	CTD	Antifolate resistance MAPK signaling pathway Ras signaling pathway +95 more
		SMO	Unknown	9581815	CTD	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SOD2	Unknown	11507057 20454814 22009531 25362851	CTD	FoxO signaling pathway Peroxisome Longevity regulating pathway +9 more
		SP1	Unknown	22009531	CTD	Endocrine resistance Mitophagy - animal TGF-beta signaling pathway +18 more
		TGFB1	Unknown	8148055	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +49 more
		TGFBR1	Unknown	21358634	CTD	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TIMP3	Unknown	36499314	CTD	Proteoglycans in cancer MicroRNAs in cancer Platelet degranulation
		XPA	Unknown	10755388 16962818	CTD	Platinum drug resistance Nucleotide excision repair Formation of Incision Complex in GG-NER +3 more
		XRCC3	Unknown	11059748 16501254	CTD	Homologous recombination HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) +2 more

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Skin neoplasms

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