Skin appendage carcinoma | Gene-Disease Associations & Pathways | GeDiPNet

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Subtype of: Skin neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
skin appendage carcinoma	MONDO_0006973	ABL1	Unknown	33252403	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ARID1A	Unknown	33252403	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ATM	Unknown	31038235	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		BRCA1	Unknown	32564423	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	32564423	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		COL1A1	Unknown	32564423	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		CTCF	Unknown	33252403	Open Targets	—
		CTNNB1	Unknown	15606674 19384065 33252403	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		FANCA	Unknown	32564423	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FBXW7	Unknown	31038235	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FLT3	Unknown	31038235 34518631	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		GATA3	Unknown	34518631	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action +6 more
		HRAS	Unknown	31038235 22683711	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		IL7R	Unknown	32564423	Open Targets	Cytokine-cytokine receptor interaction FoxO signaling pathway PI3K-Akt signaling pathway +7 more
		MET	Unknown	31038235	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		NF1	Unknown	33252403	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		PIK3CA	Unknown	31038235 33252403 21423156 34518631	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PTCH1	Unknown	31038235	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Axon guidance +7 more
		PTEN	Unknown	33252403 29269125 34518631	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		RB1	Unknown	32564423 31038235	Open Targets	Endocrine resistance Cell cycle Cellular senescence +30 more
		SDHA	Unknown	32564423	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SDHC	Unknown	32564423	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		STIL	Unknown	32564423	Open Targets	—
		TP53	Unknown	32564423 31038235 33099480 21423156 29269125 9579565	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		WRN	Unknown	32564423	Open Targets	Processive synthesis on the C-strand of the telomere Removal of the Flap Intermediate from the C-strand SUMOylation of DNA damage response and repair proteins +9 more