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Pulmonary fibrosis
Pulmonary fibrosis
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
PULMONARY FIBROSIS
C0034069
EFO_0009448
PARN
Causal
—
Disgenet
RNA degradation
ATF4 activates genes in response to endoplasmic reticulum stress
Deadenylation of mRNA
KSRP (KHSRP) binds and destabilizes mRNA
+1 more
RTEL1
Causal
—
Disgenet
Telomere Extension By Telomerase
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
SFTPC
Causal
—
Disgenet
Surfactant metabolism
Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS)
Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)
Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
+1 more
TERT
Causal
34594039
39024449
Disgenet
,
GWAS catalog
Human papillomavirus infection
Human T-cell leukemia virus 1 infection
Pathways in cancer
Hepatocellular carcinoma
Gastric cancer
Telomere Extension By Telomerase
Formation of the beta-catenin:TCF transactivating complex
+4 more
All
107
Causal
4
Unknown
103
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
4
CTD
0
HPO
0
GWAS catalog
1
GenCC
0
ClinGen
0
Related Diseases
Diseases that share the most curated genes with Pulmonary fibrosis.
5
View disease cluster →
Obstructive airway disease
27 shared genes
RTEL1, TERT, SERPINA1, ACE, CHRM3, HMOX1, HSPA1A, HSPA1B, IL1B, MBL2, TNF, IL6 +15 more
Related via 27 shared genes including RTEL1, TERT, SERPINA1.
Brain ischemia
22 shared genes
CAT, ACE, PLAU, HSPA1B, IGF1, IL1A, IL1B, PARP1, STAT3, TNF, IL6, PTGS2 +10 more
Related via 22 shared genes including CAT, ACE, PLAU.
Lung disease
21 shared genes
CAT, SERPINA1, ACE, SERPINE1, IL1A, IL1B, NFE2L2, TNF, PTGS2, PDGFA, TGFB1, CSF3 +9 more
Related via 21 shared genes including CAT, SERPINA1, ACE.
Idiopathic pulmonary fibrosis
18 shared genes
KANSL1, RTEL1, TERT, PARN, PLAU, STAT3, TNF, DSP, PTGS2, MUC5B, MUC5AC, SFTPC +6 more
Related via 18 shared genes including KANSL1, RTEL1, TERT.
Interstitial lung disease
14 shared genes
RTEL1, TERT, ARL17B, DSP, MUC5B, IL1RN, MUC5AC, SFTPC, SPDL1, FAM13A, LRRC34, SFTPA1 +2 more
Related via 14 shared genes including RTEL1, TERT, ARL17B.
1
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