eDiPNet
☰
Home
Browse
Genes
Diseases
Proteins
SNPs / Variants
Pathways ►
Reactome
KEGG
Analysis
Statistics
Resources
Blogs
Login
Contact Us
Search
Home
/
Diseases
/
Polydactyly, preaxial 4
Polydactyly, preaxial 4
Log in to bookmark this disease
Bookmark This Disease
Title
Project / Tag (optional)
Note (optional)
Cancel
Save
Subtype of:
Polydactyly
Download ▾
Download as CSV
Download as PDF
Show by gene
(one row per gene, with all of its disease terms together)
Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Polydactyly, preaxial 4
MONDO_0008272
GLI3
Unknown
10441570
Open Targets
cAMP signaling pathway
Hedgehog signaling pathway
Pathways in cancer
Basal cell carcinoma
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'off' state
Hedgehog 'on' state
GLI proteins bind promoters of Hh responsive genes to promote transcription
+5 more
Preaxial polydactyly type IV
MONDO_0008272
GLI3
Unknown
10441570
10945658
31115189
32591344
9054938
Open Targets
cAMP signaling pathway
Hedgehog signaling pathway
Pathways in cancer
Basal cell carcinoma
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'off' state
Hedgehog 'on' state
GLI proteins bind promoters of Hh responsive genes to promote transcription
+5 more
All
1
Causal
0
Unknown
1
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
1
Related Diseases
Diseases that share the most curated genes with Polydactyly, preaxial 4.
5
View disease cluster →
Tibial hemimelia
1 shared gene
GLI3
Related via 1 shared gene including GLI3.
Cronkhite-canada syndrome
1 shared gene
GLI3
Related via 1 shared gene including GLI3.
Greig cephalo-poly-syndactyly syndrome
1 shared gene
GLI3
Related via 1 shared gene including GLI3.
Pallister-hall syndrome
1 shared gene
GLI3
Related via 1 shared gene including GLI3.
Polydactyly, postaxial, types a1 and b
1 shared gene
GLI3
Related via 1 shared gene including GLI3.
1
GeDiPNet AI Assistant
Online