Subtype of: Ovarian cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ovarian clear cell adenocarcinoma	MONDO_0006045	ERBB4	Unknown	28481359 33947352 29986747	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERCC2	Unknown	33947352	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC4	Unknown	33947352	Open Targets	Nucleotide excision repair Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +4 more
		ERCC5	Unknown	33947352	Open Targets	Nucleotide excision repair Formation of Incision Complex in GG-NER Dual Incision in GG-NER +1 more
		ESR1	Unknown	33947352	Open Targets	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		ETV4	Unknown	33947352	Open Targets	Transcriptional misregulation in cancer MAPK6/MAPK4 signaling
		ETV6	Unknown	20826764	Open Targets	Transcriptional misregulation in cancer Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
		EXT2	Unknown	33947352	Open Targets	Glycosaminoglycan biosynthesis - heparan sulfate / heparin Metabolic pathways HS-GAG biosynthesis +2 more
		FANCA	Unknown	28481359 33947352	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCD2	Unknown	33947352	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
		FANCG	Unknown	33947352	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FAT1	Unknown	28481359	Open Targets	—
		FAT4	Unknown	20826764	Open Targets	Hippo signaling pathway - multiple species
		FBXO11	Unknown	23791828	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	27939411 27588476 28734796 33947352 25846456 23791828	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FGFR2	Unknown	25846456 28734796 28481359 33947352	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FGFR4	Unknown	26920370	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +20 more
		FH	Unknown	33947352	Open Targets	Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways +5 more
		FLT3	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FLT4	Unknown	33947352	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FOXO1	Unknown	33947352	Open Targets	FoxO signaling pathway AMPK signaling pathway Longevity regulating pathway +23 more
		FOXP1	Unknown	33947352	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		GATA3	Unknown	20826764	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action +6 more
		GNAS	Unknown	23791828	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		GOPC	Unknown	20826764	Open Targets	RHO GTPases regulate CFTR trafficking
		H3-3B	Unknown	20826764	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +18 more
		HGF	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +29 more
		HIF1A	Unknown	33947352	Open Targets	HIF-1 signaling pathway Mitophagy - animal Autophagy - animal +19 more
		HLA-A	Unknown	28481359	Open Targets	Endocytosis Phagosome Cellular senescence +25 more
		HNF1A	Unknown	26920370	Open Targets	Maturity onset diabetes of the young
		HOOK3	Unknown	33947352	Open Targets	Motor proteins
		HSP90AA1	Unknown	33947352	Open Targets	Protein processing in endoplasmic reticulum PI3K-Akt signaling pathway Necroptosis +56 more
		IKBKB	Unknown	33947352	Open Targets	Antifolate resistance MAPK signaling pathway Ras signaling pathway +79 more
		IL7R	Unknown	26920370 33947352	Open Targets	Cytokine-cytokine receptor interaction FoxO signaling pathway PI3K-Akt signaling pathway +7 more
		JAK3	Unknown	33947352	Open Targets	Chemokine signaling pathway PI3K-Akt signaling pathway Necroptosis +21 more
		KAT6A	Unknown	20826764	Open Targets	Signaling pathways regulating pluripotency of stem cells HATs acetylate histones Regulation of TP53 Activity through Acetylation
		KDM5C	Unknown	27939411 28481359	Open Targets	HDMs demethylate histones
		KDR	Unknown	33947352	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KEAP1	Unknown	21676886	Open Targets	Ubiquitin mediated proteolysis Parkinson disease Pathways in cancer +6 more
		KIT	Unknown	25846456	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KMT2A	Unknown	33947352 29986747	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2C	Unknown	36531003 33947352 29986747 20826764	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	26920370 33947352 29986747	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KRAS	Unknown	21926912 28734796 1656759 33947352 23716351 30851247 19349352 25846456 22271473 32616873 20942669 22487539 36531003 8319218 12648581 20826764 22705003 26920370 28481359 7852189 12694651	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LATS1	Unknown	28481359	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LIFR	Unknown	20826764	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LOC100506403	Unknown	33947352	Open Targets	—
		LOC105376156	Unknown	33947352	Open Targets	—
		LPP	Unknown	33947352	Open Targets	—
		LRP1B	Unknown	27939411 20826764	Open Targets	—

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Ovarian clear cell adenocarcinoma

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