Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
MYOCARDIAL INFARCTION	C0027051 MESH:D009203 EFO_0000612	IL18BP	Unknown	—	Disgenet	Interleukin-37 signaling Interleukin-18 signaling
		IL1B	Unknown	11743230 15883752 16310260	CTD, Disgenet	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +47 more
		IL1F10	Unknown	33532862 38072966	GWAS catalog	Cytokine-cytokine receptor interaction Interleukin-38 signaling Interleukin-36 pathway
		IL1RN	Unknown	18474815 19005744	CTD, Disgenet	Cytokine-cytokine receptor interaction Interleukin-10 signaling Interleukin-1 signaling
		IL6	Unknown	15883752 16310260	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Antifolate resistance Cytokine-cytokine receptor interaction +59 more
		IL6R	Unknown	26343387 33532862 34594039 38072966	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor +13 more
		ILF3	Unknown	38072966	GWAS catalog	—
		ILRUN	Unknown	38072966	GWAS catalog	—
		INPP5B	Unknown	33532862 38072966	GWAS catalog	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system +3 more
		INTS8	Unknown	38072966	GWAS catalog	RNA polymerase II transcribes snRNA genes
		IPO9	Unknown	33532862 38072966	GWAS catalog	Nucleocytoplasmic transport
		IRX1	Unknown	21107343 34594039	GWAS catalog	—
		ISL1	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
		ITGA1	Unknown	26708285	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +9 more
		ITGA2	Unknown	—	Disgenet	Virion - Rotavirus Phagosome PI3K-Akt signaling pathway +18 more
		ITGB3	Unknown	8598867	CTD, Disgenet	Virion - Herpesvirus Rap1 signaling pathway Hormone signaling +39 more
		ITIH4	Unknown	—	Disgenet	Platelet degranulation
		JCAD	Unknown	26343387 33532862 38072966	GWAS catalog	—
		KALRN	Unknown	33532862 38072966	GWAS catalog	NRAGE signals death through JNK Rho GTPase cycle EPHB-mediated forward signaling +3 more
		KCNE2	Unknown	19198609 26343387 26708285 33532862 34594039 37947095 38072966 39024449	GWAS catalog	Gastric acid secretion Phase 3 - rapid repolarisation Phase 2 - plateau phase
		KCNK5	Unknown	26343387 33532862 34594039 38072966	GWAS catalog	Taste transduction Protein digestion and absorption Phase 4 - resting membrane potential
		KCNN4	Unknown	—	Disgenet	Insulin secretion GnRH secretion Salivary secretion +2 more
		KDR	Unknown	—	Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KHDRBS3	Unknown	38072966	GWAS catalog	PTK6 Regulates Proteins Involved in RNA Processing
		KIAA1217	Unknown	38072966	GWAS catalog	—
		KIF6	Unknown	21943003	CTD, Disgenet	Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins
		KLF13	Unknown	29122578	CTD, Disgenet	—
		KLK1	Unknown	12411458	CTD, Disgenet	Renin-angiotensin system Endocrine and other factor-regulated calcium reabsorption Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
		KRTAP5-5	Unknown	33532862	GWAS catalog	Keratinization
		L3MBTL3	Unknown	38072966	GWAS catalog	Polycomb repressive complex
		LAMB2	Unknown	33532862 38072966	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +9 more
		LDB3	Unknown	38072966	GWAS catalog	Cytoskeleton in muscle cells
		LDHA	Unknown	3279722	CTD, Disgenet	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism +6 more
		LDLR	Unknown	33532862 34594039 39024449	GWAS catalog	Virion - Hepatitis viruses Endocytosis Ovarian steroidogenesis +12 more
		LGALS2	Unknown	15129282	CTD, Disgenet	—
		LGALS3	Unknown	29769800	CTD, Disgenet	Neutrophil degranulation RUNX1 regulates transcription of genes involved in differentiation of myeloid cells RUNX2 regulates genes involved in differentiation of myeloid cells
		LIPA	Unknown	26343387 33532862 34594039 37947095 38072966 39024449	GWAS catalog	Steroid biosynthesis Lysosome Efferocytosis +2 more
		LIPG	Unknown	38072966	Disgenet, GWAS catalog	Glycerolipid metabolism Metabolic pathways Cholesterol metabolism +1 more
		LOXL1	Unknown	38072966	GWAS catalog	Elastic fibre formation Crosslinking of collagen fibrils
		LOXL4	Unknown	38072966	GWAS catalog	Elastic fibre formation Crosslinking of collagen fibrils
		LPA	Unknown	26343387 33532862 34594039 37947095 38072966 39024449 39789286	Disgenet, GWAS catalog	Cholesterol metabolism
		LPL	Unknown	33532862 34594039 38072966	Disgenet, GWAS catalog	Glycerolipid metabolism PPAR signaling pathway Cholesterol metabolism +5 more
		LRP1	Unknown	—	Disgenet	Efferocytosis Cholesterol metabolism Alzheimer disease +3 more
		LRP8	Unknown	—	CTD, Disgenet	Platelet sensitization by LDL Retinoid metabolism and transport
		LRPAP1	Unknown	—	Disgenet	Cholesterol metabolism
		LSM8	Unknown	33532862 38072966	GWAS catalog	RNA degradation Spliceosome mRNA Splicing - Major Pathway
		LTA	Unknown	12426569 15129282	CTD, Disgenet	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor NF-kappa B signaling pathway +7 more
		LTF	Unknown	38072966	GWAS catalog	Mtb iron assimilation by chelation Neutrophil degranulation Metal sequestration by antimicrobial proteins +2 more
		MAD1L1	Unknown	33532862 38072966	GWAS catalog	Cell cycle Oocyte meiosis Progesterone-mediated oocyte maturation +8 more
		MAD2L1	Unknown	33532862 34594039 38072966	GWAS catalog	Cell cycle Oocyte meiosis Progesterone-mediated oocyte maturation +12 more
MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	MONDO:0012039	LGALS2	Unknown	—	ClinVar	—
		LRP8	Unknown	—	ClinVar	Platelet sensitization by LDL Retinoid metabolism and transport
		LTA	Unknown	—	ClinVar	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor NF-kappa B signaling pathway +7 more

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Myocardial infarction

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