Microphthalmia, isolated, with coloboma

Hedgehog signaling pathway Axon guidance Pathways in cancer Proteoglycans in cancer Basal cell carcinoma Gastric cancer Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD Release of Hh-Np from the secreting cell Ligand-receptor interactions Activation of SMO HHAT G278V abrogates palmitoylation of Hh-Np +9 more

ABC transporters Mitochondrial ABC transporters Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)

Spliceosome SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA +1 more

Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism disease events Retinoid metabolism and transport +1 more