Metabolic syndrome

Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression +4 more

Endocytosis JAK-STAT signaling pathway EGFR downregulation Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Endosomal Sorting Complex Required For Transport (ESCRT) +5 more

Stimuli-sensing channels

Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis

PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Extra-nuclear estrogen signaling Signaling by cytosolic PDGFRA and PDGFRB fusion proteins +2 more

RUNX1 regulates transcription of genes involved in differentiation of HSCs

MAPK signaling pathway

Th1 and Th2 cell differentiation Th17 cell differentiation Inflammatory bowel disease

Hippo signaling pathway Hippo signaling pathway - multiple species YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription +1 more

Post-translational modification: synthesis of GPI-anchored proteins

Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Packaging Of Telomere Ends Telomere Extension By Telomerase DNA Damage/Telomere Stress Induced Senescence +2 more

Polycomb repressive complex Major pathway of rRNA processing in the nucleolus and cytosol

Negative regulation of activity of TFAP2 (AP-2) family transcription factors Activation of the TFAP2 (AP-2) family of transcription factors TFAP2 (AP-2) family regulates transcription of growth factors and their receptors

Negative regulation of activity of TFAP2 (AP-2) family transcription factors Activation of the TFAP2 (AP-2) family of transcription factors

Cell cycle Activation of NOXA and translocation to mitochondria Transcription of E2F targets under negative control by DREAM complex Activation of PUMA and translocation to mitochondria G0 and Early G1 Pre-NOTCH Transcription and Translation SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Oxidative Stress Induced Senescence Oncogene Induced Senescence TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin D associated events in G1 Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by E2F6 Transcriptional regulation of granulopoiesis +13 more

Efferocytosis

Huntington disease

tRNA modification in the nucleus and cytosol

Neuroactive ligand-receptor interaction Hormone signaling Thyroid hormone signaling pathway Nuclear Receptor transcription pathway SUMOylation of intracellular receptors +2 more

Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins

Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins

Wnt signaling pathway Notch signaling pathway Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex Repression of WNT target genes +2 more