Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
METABOLIC DISEASE	EFO_0000589 MONDO:0005066	HAVCR1	Unknown	39024449	GWAS catalog	Virion - Flavivirus and Alphavirus Efferocytosis
		HBS1L	Unknown	39024449	GWAS catalog	mRNA surveillance pathway Legionellosis mRNA decay by 3' to 5' exoribonuclease
		HERPUD1	Unknown	39024449	GWAS catalog	Protein processing in endoplasmic reticulum ATF4 activates genes in response to endoplasmic reticulum stress
		HGFAC	Unknown	39024449	GWAS catalog	MET Receptor Activation
		HK1	Unknown	39024449	GWAS catalog	Glycolysis / Gluconeogenesis Fructose and mannose metabolism Galactose metabolism +14 more
		HLA-DQB1	Unknown	39024449	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HMGCR	Unknown	39024449	GWAS catalog	Terpenoid backbone biosynthesis Metabolic pathways AMPK signaling pathway +5 more
		HNF1A	Unknown	39024449	GWAS catalog	Maturity onset diabetes of the young
		IGF2BP1	Unknown	39024449	GWAS catalog	MicroRNAs in cancer Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA MAPK6/MAPK4 signaling
		INSIG2	Unknown	39024449	GWAS catalog	—
		JAK2	Unknown	39024449	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
		LDLR	Unknown	39024449	GWAS catalog	Virion - Hepatitis viruses Endocytosis Ovarian steroidogenesis +12 more
		LPA	Unknown	39024449	GWAS catalog	Cholesterol metabolism
		LPL	Unknown	39024449	GWAS catalog	Glycerolipid metabolism PPAR signaling pathway Cholesterol metabolism +5 more
		MAIP1	Unknown	39024449	GWAS catalog	Processing of SMDT1
		MAML2	Unknown	39024449	GWAS catalog	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MBOAT1	Unknown	39024449	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +2 more
		MPC2	Unknown	36417180	Disgenet	Diabetic cardiomyopathy
		MYB	Unknown	39024449	GWAS catalog	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYO1D	Unknown	40465716	GWAS catalog	Motor proteins Pathogenic Escherichia coli infection
		NAT2	Unknown	39024449	GWAS catalog	Caffeine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		NPC1L1	Unknown	39024449	GWAS catalog	Fat digestion and absorption Intestinal lipid absorption
		NYAP2	Unknown	39024449	GWAS catalog	—
		PCCB	Unknown	39024449	GWAS catalog	Valine, leucine and isoleucine degradation Glyoxylate and dicarboxylate metabolism Propanoate metabolism +5 more
		PCSK9	Unknown	39024449	GWAS catalog	Cholesterol metabolism Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) VLDLR internalisation and degradation +2 more
		PGCKA1	Unknown	35096005	GWAS catalog	—
		PGF	Unknown	35096005	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +5 more
		PIWIL1	Unknown	40465716	GWAS catalog	—
		PMFBP1	Unknown	39024449	GWAS catalog	—
		PNPLA3	Unknown	39024449	GWAS catalog	Glycerolipid metabolism Metabolic pathways Acyl chain remodeling of DAG and TAG
		PSD3	Unknown	39024449	GWAS catalog	Endocytosis
		PSMD2	Unknown	39024449	GWAS catalog	Proteasome Alzheimer disease Parkinson disease +58 more
		PUM2	Unknown	39024449	GWAS catalog	Spinocerebellar ataxia Neddylation
		RBFOX1	Unknown	35096005 39024449	GWAS catalog	—
		RPIA	Unknown	35096005	GWAS catalog	Pentose phosphate pathway Metabolic pathways Carbon metabolism +4 more
		SCARB1	Unknown	39024449	GWAS catalog	Virion - Hepatitis viruses Phagosome Ovarian steroidogenesis +10 more
		SERPINB11	Unknown	39024449	GWAS catalog	—
		SHROOM3	Unknown	39024449	GWAS catalog	—
		SLC17A2	Unknown	39024449	GWAS catalog	—
		SMARCA4	Unknown	39024449	GWAS catalog	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		SPATS2L	Unknown	39024449	GWAS catalog	—
		ST3GAL4	Unknown	39024449	GWAS catalog	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways Keratan sulfate biosynthesis +4 more
		SYN2	Unknown	39024449	GWAS catalog	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
		TAFA5	Unknown	39024449	GWAS catalog	—
		TBX2	Unknown	39024449	GWAS catalog	—
		TCF7L2	Unknown	39024449	GWAS catalog	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TDRD15	Unknown	39024449	GWAS catalog	—
		TIMD4	Unknown	39024449	GWAS catalog	Efferocytosis
		TM6SF2	Unknown	39024449	GWAS catalog	—
		TMPRSS6	Unknown	39024449	GWAS catalog	Collagen degradation Degradation of the extracellular matrix
METABOLIC DISEASES	C0025517	MPC2	Unknown	—	Disgenet	Diabetic cardiomyopathy
METABOLIC SYNDROME	EFO_0000195	HAVCR1	Unknown	33893285	GWAS catalog	Virion - Flavivirus and Alphavirus Efferocytosis
		HERPUD1	Unknown	20694148 21386085 22399527 31589552 33500527 33893285 38201907 39349817	GWAS catalog	Protein processing in endoplasmic reticulum ATF4 activates genes in response to endoplasmic reticulum stress
		HGFAC	Unknown	39349817	GWAS catalog	MET Receptor Activation
		HLA-DQB1	Unknown	33893285	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HMGCR	Unknown	33893285	GWAS catalog	Terpenoid backbone biosynthesis Metabolic pathways AMPK signaling pathway +5 more
		IGF2BP1	Unknown	39349817	GWAS catalog	MicroRNAs in cancer Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA MAPK6/MAPK4 signaling
		LDLR	Unknown	33893285	GWAS catalog	Virion - Hepatitis viruses Endocytosis Ovarian steroidogenesis +12 more
		LPA	Unknown	31589552 33893285 39349817	GWAS catalog	Cholesterol metabolism
		LPL	Unknown	20694148 21386085 22399527 29632305 30382898 31589552 33500527 38201907 39349817	GWAS catalog	Glycerolipid metabolism PPAR signaling pathway Cholesterol metabolism +5 more
		NAT2	Unknown	31589552 39349817	GWAS catalog	Caffeine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		NYAP2	Unknown	31589552 39349817	GWAS catalog	—
		PCCB	Unknown	31589552 39349817	GWAS catalog	Valine, leucine and isoleucine degradation Glyoxylate and dicarboxylate metabolism Propanoate metabolism +5 more
		PCSK9	Unknown	33893285	GWAS catalog	Cholesterol metabolism Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) VLDLR internalisation and degradation +2 more
		PMFBP1	Unknown	39349817	GWAS catalog	—
		PSD3	Unknown	31589552 39349817	GWAS catalog	Endocytosis
		RBFOX1	Unknown	39349817	GWAS catalog	—
		SCARB1	Unknown	39349817	GWAS catalog	Virion - Hepatitis viruses Phagosome Ovarian steroidogenesis +10 more
		SMARCA4	Unknown	33893285	GWAS catalog	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		ST3GAL4	Unknown	33893285	GWAS catalog	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways Keratan sulfate biosynthesis +4 more
		SYN2	Unknown	39349817	GWAS catalog	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
		TAFA5	Unknown	39349817	GWAS catalog	—
		TCF7L2	Unknown	20694148 39349817	GWAS catalog	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TDRD15	Unknown	39349817	GWAS catalog	—
		TIMD4	Unknown	33893285	GWAS catalog	Efferocytosis
		TM6SF2	Unknown	39349817	GWAS catalog	—

«‹123 4…27 ›»

Metabolic syndrome

Bookmark This Disease