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Melanoma-pancreatic cancer syndrome
Melanoma-pancreatic cancer syndrome
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
melanoma-pancreatic cancer syndrome
MONDO_0018453
CDKN2A
Causal
10797439
17440112
20132244
24451801
24884915
26794401
28699883
28754699
29263814
30207590
30558719
32482799
35422439
38936911
8317504
9622062
ClinGen
,
Open Targets
Endocrine resistance
Platinum drug resistance
Cell cycle
p53 signaling pathway
Cellular senescence
Cushing syndrome
Human cytomegalovirus infection
Human T-cell leukemia virus 1 infection
Pathways in cancer
Viral carcinogenesis
MicroRNAs in cancer
Pancreatic cancer
Glioma
Melanoma
Bladder cancer
Chronic myeloid leukemia
Non-small cell lung cancer
Hepatocellular carcinoma
Apoptotic factor-mediated response
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
Regulation of TP53 Degradation
Cyclin D associated events in G1
Stabilization of p53
Transcriptional Regulation by VENTX
Regulation of RUNX3 expression and activity
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
Evasion of Oncogene Induced Senescence Due to p14ARF Defects
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects
+33 more
CDK4
Unknown
7666917
Open Targets
Endocrine resistance
Cell cycle
p53 signaling pathway
PI3K-Akt signaling pathway
Cellular senescence
Tight junction
T cell receptor signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Cushing syndrome
Hepatitis C
Measles
Human cytomegalovirus infection
Influenza A
Human papillomavirus infection
Human T-cell leukemia virus 1 infection
Kaposi sarcoma-associated herpesvirus infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Pancreatic cancer
Glioma
Melanoma
Bladder cancer
Chronic myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Breast cancer
Hepatocellular carcinoma
SCF(Skp2)-mediated degradation of p27/p21
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
RMTs methylate histone arginines
Transcriptional regulation of white adipocyte differentiation
Cyclin D associated events in G1
Ubiquitin-dependent degradation of Cyclin D
PTK6 Regulates Cell Cycle
Transcriptional regulation by RUNX2
Transcriptional regulation of granulopoiesis
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
+40 more
All
2
Causal
1
Unknown
1
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
1
Open Targets
2
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Related via 2 shared genes including CDKN2A, CDK4.
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1 shared gene
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Related via 1 shared gene including CDKN2A.
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1 shared gene
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Related via 1 shared gene including CDKN2A.
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1 shared gene
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Related via 1 shared gene including CDKN2A.
1
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