Mast cell neoplasm

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Pathways column key: KEGG Reactome
Disease Term Disease ID Gene Symbol Classification References Source Pathways
mast cell neoplasm
MONDO_0002724
ASXL1 Unknown
22905207 30373888 32843387
Open Targets
CBL Unknown
23074272 26728869
Open Targets
DNMT3A Unknown
22905207 30373888
Open Targets
EPHA7 Unknown
30373888
Open Targets
EZH2 Unknown
30373888
Open Targets
IDH2 Unknown
26728869
Open Targets
IKZF1 Unknown
30373888
Open Targets —
JAK2 Unknown
23074272 23958953 22608575
Open Targets
EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
KAT6B Unknown
30373888
Open Targets
KIT Unknown
10706069 11377687 11380399 12007509 12091362 12519307 12801532 15371947 15377487 15507672 15512820 15722637 15972446 16400343 16741248 16779792 17259998 17451799 17551405 18165278 18404201 18448146 18509466 18579792 18931652 19021706 19034614 19135713 19193436 19262599 19541349 19883434 20038218 20061010 20112369 20471335 20551067 20553795 20685234 21108325 21134978 21354053 21362052 21656905 22173243 22324351 22469616 22608575 22905207 23074272 23092007 23196796 23374274 23388130 23958953 24465546 25034364 25264491 25695690 26728869 27104187 28236058 30373888 32843387 39621254 7479840 7691885 8589724 9029028 9858225
Open Targets
LOC100506403 Unknown
30373888
Open Targets —
NPM1 Unknown
26728869
Open Targets
NRAS Unknown
21134978
Open Targets
EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +130 more
ROS1 Unknown
30373888
Open Targets —
SF3B1 Unknown
23831919 30373888
Open Targets
SRSF2 Unknown
30373888 26728869 24389310
Open Targets
All16 Causal0 Unknown16
Related Diseases Diseases that share the most curated genes with Mast cell neoplasm.
5 View disease cluster →
Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease 12 shared genesIDH2, JAK2, NRAS, DNMT3A, KIT, SF3B1, ASXL1, NPM1, EZH2, SRSF2, CBL, LOC100506403 Related via 12 shared genes including IDH2, JAK2, NRAS. Therapy-related myeloid neoplasm 10 shared genesIDH2, JAK2, NRAS, DNMT3A, KIT, ASXL1, NPM1, EZH2, SRSF2, LOC100506403 Related via 10 shared genes including IDH2, JAK2, NRAS. Cd4+/cd56+ hematodermic neoplasm 12 shared genesIKZF1, IDH2, JAK2, NRAS, DNMT3A, KIT, SF3B1, ASXL1, NPM1, EZH2, SRSF2, LOC100506403 Related via 12 shared genes including IKZF1, IDH2, JAK2. Therapy related acute myeloid leukemia and myelodysplastic syndrome 12 shared genesIKZF1, IDH2, JAK2, NRAS, DNMT3A, SF3B1, ASXL1, NPM1, EZH2, SRSF2, CBL, LOC100506403 Related via 12 shared genes including IKZF1, IDH2, JAK2. Chronic eosinophilic leukemia, not otherwise specified 12 shared genesIKZF1, IDH2, JAK2, NRAS, DNMT3A, KIT, SF3B1, ASXL1, EZH2, SRSF2, CBL, LOC100506403 Related via 12 shared genes including IKZF1, IDH2, JAK2.