Subtype of: Lymphoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
mantle cell lymphoma	MONDO_0018876	LATS2	Unknown	24145436	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LHFPL6	Unknown	24145436	Open Targets	—
		LIFR	Unknown	24145436	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LMNA	Unknown	37605345	Open Targets	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LOC100506403	Unknown	24145436	Open Targets	—
		LOC124905021	Unknown	24145436	Open Targets	—
		LPP	Unknown	24145436	Open Targets	—
		LRIG3	Unknown	24145436	Open Targets	—
		LRP1B	Unknown	24145436 37605345	Open Targets	—
		MALT1	Unknown	24145436	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		MAML2	Unknown	24145436	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K4	Unknown	24145436	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MAP3K13	Unknown	24145436	Open Targets	MAPK signaling pathway
		MAX	Unknown	28481359	Open Targets	Polycomb repressive complex MAPK signaling pathway Pathways in cancer +6 more
		MDM4	Unknown	24145436	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MECOM	Unknown	24145436	Open Targets	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MED12	Unknown	24145436	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MITF	Unknown	24145436	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLF1	Unknown	24145436	Open Targets	Transcriptional misregulation in cancer
		MLH1	Unknown	24145436	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MLLT3	Unknown	24145436	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MNX1	Unknown	24145436	Open Targets	Maturity onset diabetes of the young
		MRTFA	Unknown	24145436	Open Targets	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH2	Unknown	24145436	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MSH6	Unknown	25082755	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		MSI2	Unknown	24145436	Open Targets	mRNA surveillance pathway
		MTOR	Unknown	24145436 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC16	Unknown	24145436 37605345	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC4	Unknown	24145436	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC6	Unknown	37605345	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYC	Unknown	31433838	Open Targets	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more
		MYH11	Unknown	24145436 37605345	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		MYH9	Unknown	24145436	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +8 more
		N4BP2	Unknown	24145436	Open Targets	—
		NACA	Unknown	24145436	Open Targets	Parathyroid hormone synthesis, secretion and action
		NBEA	Unknown	24145436	Open Targets	—
		NBN	Unknown	24145436	Open Targets	Homologous recombination Cellular senescence DNA Damage/Telomere Stress Induced Senescence +13 more
		NCOA1	Unknown	24145436	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NCOA2	Unknown	24145436	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway RORA activates gene expression +14 more
		NCOR1	Unknown	24145436	Open Targets	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NCOR2	Unknown	37605345	Open Targets	Notch signaling pathway Epstein-Barr virus infection PPARA activates gene expression +11 more
		NF1	Unknown	24145436	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NF2	Unknown	24145436	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Tight junction +2 more
		NFATC2	Unknown	37605345	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Efferocytosis +24 more
		NFIB	Unknown	24145436	Open Targets	—
		NFKBIE	Unknown	37605345 25987724	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation T cell receptor signaling pathway +6 more
		NIN	Unknown	24682267	Open Targets	—
		NOTCH1	Unknown	22210878 24145436 37605345 23407552 24682267 28633365	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +20 more
		NOTCH2	Unknown	24145436 37605345 31433838 28481359	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NPM1	Unknown	8558920 8781434	Open Targets	Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere +2 more

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Mantle cell lymphoma

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