Subtype of: Lymphoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
mantle cell lymphoma	MONDO_0018876	ATM	Causal	28481359 16461462 16387360 34646650 22210878 10706620 27224912 24145436 37605345 23407552 29386642 11756177 24682267 10397742 12697903	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ABL1	Unknown	24145436	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ABL2	Unknown	24145436	Open Targets	ErbB signaling pathway Ras signaling pathway Chemical carcinogenesis - reactive oxygen species +2 more
		AFF1	Unknown	24145436	Open Targets	Transcriptional misregulation in cancer
		AFF3	Unknown	24145436	Open Targets	—
		ALK	Unknown	8558920 24145436 8781434	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		ANK1	Unknown	24145436	Open Targets	Proteoglycans in cancer Interaction between L1 and Ankyrins Neurofascin interactions +1 more
		ARHGAP26	Unknown	24145436	Open Targets	Rho GTPase cycle
		ARHGEF10	Unknown	24145436	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARHGEF10L	Unknown	24145436	Open Targets	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		ARID1A	Unknown	37605345 31433838 28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	24145436	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	24145436 37605345 28481359	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ARNT	Unknown	24145436	Open Targets	HIF-1 signaling pathway Efferocytosis Cushing syndrome +10 more
		ASPM	Unknown	24145436	Open Targets	—
		ASXL1	Unknown	24145436 37605345 29386642	Open Targets	Polycomb repressive complex UCH proteinases
		ATIC	Unknown	24145436	Open Targets	Purine metabolism One carbon pool by folate Metabolic pathways +2 more
		ATP2B3	Unknown	24145436	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +9 more
		ATR	Unknown	24145436 25082755	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		ATRX	Unknown	24145436	Open Targets	Cell cycle
		AXIN1	Unknown	28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AXIN2	Unknown	24145436	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		B2M	Unknown	24145436	Open Targets	Antigen processing and presentation Human cytomegalovirus infection Human T-cell leukemia virus 1 infection +14 more
		BAP1	Unknown	24145436	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BCL11B	Unknown	24145436	Open Targets	Transcriptional misregulation in cancer
		BCL2	Unknown	24145436	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BCL6	Unknown	24145436	Open Targets	FoxO signaling pathway Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation +3 more
		BCL9L	Unknown	37605345	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCLAF1	Unknown	24145436	Open Targets	—
		BCOR	Unknown	37605345 28481359	Open Targets	Polycomb repressive complex
		BIRC3	Unknown	24145436 27224912 37605345 24682267 28481359 24362935	Open Targets	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		BIRC6	Unknown	37605345	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BMP5	Unknown	24145436	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway
		BMPR1A	Unknown	24145436	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		BRAF	Unknown	24145436	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	24145436	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	24145436 28481359	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BTK	Unknown	25082755	Open Targets	NF-kappa B signaling pathway Osteoclast differentiation Platelet activation +17 more
		CACNA1D	Unknown	24145436	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CALR	Unknown	27224912	Open Targets	Protein processing in endoplasmic reticulum Phagosome Efferocytosis +14 more
		CAMTA1	Unknown	24145436	Open Targets	—
		CARD11	Unknown	24145436 27224912 37605345	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CARS1	Unknown	37605345	Open Targets	Aminoacyl-tRNA biosynthesis Cytosolic tRNA aminoacylation
		CASP8	Unknown	24145436	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CBLC	Unknown	24145436	Open Targets	Ubiquitin mediated proteolysis Endocytosis
		CCND1	Unknown	24145436 37605345 24682267 22210878 28481359	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CCND3	Unknown	24145436	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +17 more
		CD79B	Unknown	37605345	Open Targets	B cell receptor signaling pathway CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
		CDH10	Unknown	24145436	Open Targets	Adherens junctions interactions
		CDH11	Unknown	24145436 37605345	Open Targets	Adherens junctions interactions

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Mantle cell lymphoma

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