Mantle cell lymphoma

Downregulation of SMAD2/3:SMAD4 transcriptional activity

Spliceosome Shigellosis Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination +3 more

Ubiquitin mediated proteolysis

Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Peroxisomal protein import Amyloid fiber formation +2 more

SNARE interactions in vesicular transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network

Transcriptional misregulation in cancer

Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo YAP1- and WWTR1 (TAZ)-stimulated gene expression SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Physiological factors RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination +5 more

Hippo signaling pathway Hippo signaling pathway - multiple species Nuclear signaling by ERBB4 Signaling by Hippo YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX1 regulates transcription of genes involved in differentiation of HSCs RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination +5 more

Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia Neddylation Antigen processing: Ubiquitination & Proteasome degradation +2 more

Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription

Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease

Generic Transcription Pathway

Wnt signaling pathway Regulation of FZD by ubiquitination