Subtype of: Lymphoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
mantle cell lymphoma	MONDO_0018876	ROBO2	Unknown	24145436 24682267	Open Targets	Axon guidance Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO
		ROCK1	Unknown	37605345	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Chemokine signaling pathway +25 more
		ROS1	Unknown	24145436	Open Targets	—
		RPN1	Unknown	24145436	Open Targets	N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways +2 more
		RSPO2	Unknown	24145436	Open Targets	Wnt signaling pathway Regulation of FZD by ubiquitination
		RSPO3	Unknown	24145436	Open Targets	Wnt signaling pathway Regulation of FZD by ubiquitination RUNX1 regulates transcription of genes involved in WNT signaling
		SDHA	Unknown	28481359	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SDHC	Unknown	24145436	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SDHD	Unknown	24145436	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SEPTIN9	Unknown	24145436	Open Targets	Bacterial invasion of epithelial cells Shigellosis
		SETBP1	Unknown	29386642	Open Targets	—
		SETD2	Unknown	27224912	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SFPQ	Unknown	24145436	Open Targets	PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
		SGK1	Unknown	37605345	Open Targets	FoxO signaling pathway Efferocytosis mTOR signaling pathway +6 more
		SHTN1	Unknown	24145436 37605345	Open Targets	—
		SIX2	Unknown	24145436	Open Targets	—
		SLC34A2	Unknown	24145436	Open Targets	Parathyroid hormone synthesis, secretion and action Mineral absorption Type II Na+/Pi cotransporters +2 more
		SMAD2	Unknown	27224912	Open Targets	Cell cycle Endocytosis Cellular senescence +30 more
		SMARCA4	Unknown	24145436 27224912 24682267 37605345	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		SMARCB1	Unknown	24145436	Open Targets	ATP-dependent chromatin remodeling Viral life cycle - HIV-1 Thermogenesis +3 more
		SMC1A	Unknown	24682267 29386642	Open Targets	Cell cycle Oocyte meiosis Separation of Sister Chromatids +5 more
		SND1	Unknown	24145436	Open Targets	Viral carcinogenesis Signaling by BRAF and RAF fusions
		SNX29	Unknown	24145436	Open Targets	—
		SOCS1	Unknown	19734449	Open Targets	Ubiquitin mediated proteolysis Osteoclast differentiation JAK-STAT signaling pathway +13 more
		SOS1	Unknown	24145436	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +97 more
		SPEN	Unknown	28481359	Open Targets	Notch signaling pathway
		STAG1	Unknown	24145436	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAG2	Unknown	24145436	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAT3	Unknown	27224912 28481359 29386642	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		STIL	Unknown	24145436	Open Targets	—
		STRN	Unknown	24145436	Open Targets	PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling +2 more
		SUB1	Unknown	24145436	Open Targets	—
		SUZ12	Unknown	37605345	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +5 more
		SYK	Unknown	16409295 19549911	Open Targets	NF-kappa B signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway +30 more
		TBL1XR1	Unknown	24145436	Open Targets	Wnt signaling pathway RORA activates gene expression PPARA activates gene expression +11 more
		TBX3	Unknown	24145436	Open Targets	Signaling pathways regulating pluripotency of stem cells
		TCF3	Unknown	24145436	Open Targets	Signaling pathways regulating pluripotency of stem cells Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer +2 more
		TENT5C	Unknown	24145436	Open Targets	—
		TERT	Unknown	24145436	Open Targets	Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer +4 more
		TET2	Unknown	23407552 29386642	Open Targets	—
		TFEB	Unknown	24145436	Open Targets	Calcium signaling pathway Mitophagy - animal
		TGFBR2	Unknown	37605345	Open Targets	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TNC	Unknown	24145436	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +6 more
		TNRC18	Unknown	24145436	Open Targets	—
		TP53	Unknown	16461462 31433838 34646650 22210878 8605352 8639789 10956404 23407552 24145436 25082755 37605345 24682267 28481359	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TP63	Unknown	24145436	Open Targets	MicroRNAs in cancer Activation of PUMA and translocation to mitochondria TP53 Regulates Metabolic Genes +5 more
		TPM4	Unknown	24145436	Open Targets	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +5 more
		TPR	Unknown	24145436	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis Pathways in cancer +27 more
		TRAF7	Unknown	24145436	Open Targets	Antigen processing: Ubiquitination & Proteasome degradation
		TRIM24	Unknown	37605345	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by BRAF and RAF fusions

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Mantle cell lymphoma

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