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Laurin-sandrow syndrome
Laurin-sandrow syndrome
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Pathways column key:
KEGG
Reactome
Disease terms
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Laurin-Sandrow syndrome
MONDO_0007615
LMBR1
Unknown
11090342
24456159
26749485
Open Targets
—
Laurin-Sandrow syndrome
MONDO_0007615
SHH
Unknown
24456159
Open Targets
Hedgehog signaling pathway
Axon guidance
Pathways in cancer
Proteoglycans in cancer
Basal cell carcinoma
Gastric cancer
Hedgehog ligand biogenesis
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
Release of Hh-Np from the secreting cell
Ligand-receptor interactions
Activation of SMO
HHAT G278V abrogates palmitoylation of Hh-Np
+9 more
All
2
Causal
0
Unknown
2
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
2
Related Diseases
Diseases that share the most curated genes with Laurin-sandrow syndrome.
5
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Triphalangeal thumb-polysyndactyly syndrome
2 shared genes
LMBR1, SHH
Related via 2 shared genes including LMBR1, SHH.
Preaxial polydactyly 2
2 shared genes
LMBR1, SHH
Related via 2 shared genes including LMBR1, SHH.
Hypoplasia or aplasia of tibia with polydactyly
2 shared genes
LMBR1, SHH
Related via 2 shared genes including LMBR1, SHH.
Acheiropody
1 shared gene
LMBR1
Related via 1 shared gene including LMBR1.
Patterson stevenson fontaine syndrome
1 shared gene
LMBR1
Related via 1 shared gene including LMBR1.
1
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