Keratocystic odontogenic tumor | Gene-Disease Associations & Pathways | GeDiPNet

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Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
Keratocystic odontogenic tumor	MONDO_0018648	ATM	Unknown	29272070	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		BRAF	Unknown	29272070	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		FBXW7	Unknown	29272070	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		JAK2	Unknown	29272070	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
		KDR	Unknown	29272070	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KIT	Unknown	29272070	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		MET	Unknown	29272070	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		PIK3CA	Unknown	29272070	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		PTCH1	Unknown	23953420 20659694 18502968 24204797 16931872 25458233 15308259 10890722 19362041	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Axon guidance +7 more
		PTEN	Unknown	29272070	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		SMO	Unknown	29272070	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		TP53	Unknown	29272070	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more