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Interstitial lung disease 2
Interstitial lung disease 2
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Subtype of:
Interstitial lung disease
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
Interstitial lung disease 2
EFO_0000768
MONDO_0100220
MONDO_0015925
SFTPA2
Causal
19100526
21506741
21506748
26568241
26792177
32855221
ClinGen
,
Open Targets
Phagosome
Pertussis
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Signal regulatory protein family interactions
Surfactant metabolism
Regulation of TLR by endogenous ligand
Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF)
Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)
Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
+7 more
FARSA
Unknown
31355908
Open Targets
Aminoacyl-tRNA biosynthesis
Cytosolic tRNA aminoacylation
MUC5B
Unknown
26792177
21506741
32855221
19100526
21506748
Open Targets
IL-17 signaling pathway
Salivary secretion
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Dectin-2 family
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis
+5 more
All
3
Causal
1
Unknown
2
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
1
Open Targets
3
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Diffuse panbronchiolitis
1 shared gene
MUC5B
Related via 1 shared gene including MUC5B.
Antithrombin deficiency
1 shared gene
MUC5B
Related via 1 shared gene including MUC5B.
Bronchiolitis
1 shared gene
MUC5B
Related via 1 shared gene including MUC5B.
Extrinsic allergic alveolitis
1 shared gene
MUC5B
Related via 1 shared gene including MUC5B.
Interstitial lung disease
3 shared genes
MUC5B, SFTPA2, FARSA
Related via 3 shared genes including MUC5B, SFTPA2, FARSA.
1
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