Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
GRAVES DISEASE	EFO_0004237 C0018213 MESH:D006111	AAMDC	Unknown	31050781	GWAS catalog	—
		ABCF1	Unknown	21900946	GWAS catalog	ABC-family proteins mediated transport
		ABO	Unknown	21841780 23612905	GWAS catalog	Glycosphingolipid biosynthesis - lacto and neolacto series Glycosphingolipid biosynthesis - globo and isoglobo series Metabolic pathways +1 more
		ACAD10	Unknown	34594039	GWAS catalog	Mitochondrial Fatty Acid Beta-Oxidation
		ADRB2	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +13 more
		ALDH2	Unknown	34594039	GWAS catalog	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid degradation +14 more
		ANKS1A	Unknown	34594039	GWAS catalog	—
		ARID5B	Unknown	22446963 34594039	CTD, Disgenet, GWAS catalog	HDMs demethylate histones
		B3GNT2	Unknown	22446963	CTD, Disgenet	Glycosaminoglycan biosynthesis - keratan sulfate Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways +2 more
		BACH2	Unknown	21841780 22922229 34594039	GWAS catalog	—
		BLTP3A	Unknown	34594039	GWAS catalog	—
		BTNL2	Unknown	—	Disgenet	Butyrophilin (BTN) family interactions
		C1QTNF6	Unknown	23612905	GWAS catalog	—
		C4A	Unknown	—	Disgenet	Complement and coagulation cascades Alcoholic liver disease Pertussis +8 more
		C4B	Unknown	—	Disgenet	Complement and coagulation cascades Alcoholic liver disease Pertussis +8 more
		C6ORF15	Unknown	21841780 31050781	GWAS catalog	—
		CCR6	Unknown	34594039	GWAS catalog	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +3 more
		CD4	Unknown	33132244	CTD, Disgenet	Viral life cycle - HIV-1 Virion - Human immunodeficiency virus Cytokine-cytokine receptor interaction +23 more
		CD40	Unknown	32514122 34594039	Disgenet, GWAS catalog	Cytokine-cytokine receptor interaction NF-kappa B signaling pathway Cell adhesion molecules +17 more
		CD40LG	Unknown	—	Disgenet	Cytokine-cytokine receptor interaction NF-kappa B signaling pathway Cell adhesion molecules +14 more
		CEP43	Unknown	34594039	GWAS catalog	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		CTLA4	Unknown	19731979 21841780 23104008 22922229 32514122 34594039 39024449	CTD, Disgenet, GWAS catalog	Cell adhesion molecules T cell receptor signaling pathway Autoimmune thyroid disease +3 more
		CYP1A1	Unknown	—	Disgenet	Steroid hormone biosynthesis Tryptophan metabolism Retinol metabolism +12 more
		DCHS2	Unknown	31050781	GWAS catalog	Hippo signaling pathway - multiple species
		DNMT1	Unknown	—	Disgenet	Cysteine and methionine metabolism Metabolic pathways MicroRNAs in cancer +2 more
		DTWD2	Unknown	39024449	GWAS catalog	—
		ESR2	Unknown	—	Disgenet	Endocrine resistance Hormone signaling Estrogen signaling pathway +11 more
		FAM76B	Unknown	22922229 34594039	GWAS catalog	—
		FBXL19	Unknown	34594039	GWAS catalog	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FCRL3	Unknown	21841780 32514122 34594039	CTD, GWAS catalog	—
		FKBP1B	Unknown	—	Disgenet	Stimuli-sensing channels Ion homeostasis
		GC	Unknown	12050214	CTD, Disgenet	Vitamin D (calciferol) metabolism
		GPR174	Unknown	34594039	GWAS catalog	—
		GPR26	Unknown	39024449	GWAS catalog	—
		GSTP1	Unknown	—	Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +11 more
		HLA-B	Unknown	—	Disgenet	Endocytosis Phagosome Cellular senescence +24 more
		HLA-DPA1	Unknown	34594039	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DQA1	Unknown	39024449 40465716	Disgenet, GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DQB1	Unknown	21841780 31050781	Disgenet, GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DRB1	Unknown	40465716	Disgenet, GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DRB3	Unknown	—	Disgenet	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		ICAM1	Unknown	—	Disgenet	NF-kappa B signaling pathway Cell adhesion molecules Natural killer cell mediated cytotoxicity +19 more
		ICOS	Unknown	22922229 39024449	GWAS catalog	Cell adhesion molecules T cell receptor signaling pathway Intestinal immune network for IgA production +5 more
		IFIH1	Unknown	17535987	CTD, Disgenet	RIG-I-like receptor signaling pathway Hepatitis B Measles +11 more
		IFNG	Unknown	33132244	CTD, Disgenet	Proteasome Cytokine-cytokine receptor interaction HIF-1 signaling pathway +33 more
		IL10	Unknown	—	Disgenet	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +25 more
		IL13	Unknown	—	Disgenet	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway IL-17 signaling pathway +7 more
		IL17A	Unknown	33132244	CTD, Disgenet	Cytokine-cytokine receptor interaction IL-17 signaling pathway Th17 cell differentiation +5 more
		IL1B	Unknown	—	Disgenet	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +47 more
		IL2	Unknown	—	Disgenet	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor PI3K-Akt signaling pathway +21 more

«‹12 ›»

Graves disease

Bookmark This Disease