Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
gallbladder adenoma	MONDO_0006216	ACVR1B	Unknown	34362903	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		ALK	Unknown	34362903 25680569	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		APC	Unknown	34362903	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		ARAF	Unknown	34362903	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +41 more
		ARHGAP5	Unknown	34362903	Open Targets	Focal adhesion Leukocyte transendothelial migration Rho GTPase cycle
		ARHGEF12	Unknown	34362903	Open Targets	Vascular smooth muscle contraction Axon guidance Platelet activation +12 more
		ARID1B	Unknown	34362903	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	34362903	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		ATIC	Unknown	34362903	Open Targets	Purine metabolism One carbon pool by folate Metabolic pathways +2 more
		BCLAF1	Unknown	34362903	Open Targets	—
		BCOR	Unknown	34362903	Open Targets	Polycomb repressive complex
		BRAF	Unknown	21307665	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	34362903	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	34362903	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		CACNA1D	Unknown	34362903	Open Targets	MAPK signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +35 more
		CBLB	Unknown	34362903	Open Targets	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis +5 more
		CCND1	Unknown	34362903	Open Targets	Endocrine resistance FoxO signaling pathway Cell cycle +58 more
		CLTC	Unknown	34362903	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CNOT3	Unknown	34362903	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		COL2A1	Unknown	34362903	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		CREBBP	Unknown	34362903	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CSMD3	Unknown	34362903	Open Targets	—
		CTNNA2	Unknown	34362903	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNNB1	Unknown	34362903 11309300 29975247 11196159 12023580 25680569	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND2	Unknown	34362903	Open Targets	Wnt signaling pathway
		DCAF12L2	Unknown	34362903	Open Targets	—
		DCTN1	Unknown	34362903	Open Targets	Motor proteins Vasopressin-regulated water reabsorption Amyotrophic lateral sclerosis +15 more
		DDX3X	Unknown	34362903	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		DNMT3A	Unknown	34362903	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		EGFR	Unknown	34362903	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EIF1AX	Unknown	34362903	Open Targets	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits +3 more
		EIF3E	Unknown	34362903	Open Targets	Hepatitis C L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation +4 more
		ELF3	Unknown	34362903	Open Targets	Pre-NOTCH Transcription and Translation
		ELF4	Unknown	34362903	Open Targets	—
		EML4	Unknown	25680569	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer +1 more
		ERBB2	Unknown	34362903	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB3	Unknown	34362903	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERCC4	Unknown	34362903	Open Targets	Nucleotide excision repair Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +4 more
		ERCC5	Unknown	34362903	Open Targets	Nucleotide excision repair Formation of Incision Complex in GG-NER Dual Incision in GG-NER +1 more
		ESR1	Unknown	34362903	Open Targets	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		ETV1	Unknown	34362903	Open Targets	Transcriptional misregulation in cancer
		FAM131B	Unknown	34362903	Open Targets	Signaling by BRAF and RAF fusions
		FANCE	Unknown	34362903	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCG	Unknown	34362903	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FAT4	Unknown	34362903	Open Targets	Hippo signaling pathway - multiple species
		FBLN2	Unknown	34362903	Open Targets	Cytoskeleton in muscle cells Molecules associated with elastic fibres
		FBXO11	Unknown	34362903	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FLNA	Unknown	34362903	Open Targets	MAPK signaling pathway Focal adhesion Salmonella infection +6 more
		FNBP1	Unknown	34362903	Open Targets	Shigellosis Clathrin-mediated endocytosis
		GMPS	Unknown	34362903	Open Targets	Purine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more

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Gallbladder adenoma

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