Subtype of: Breast cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
female breast carcinoma	MONDO_0004379	MAP2K4	Unknown	11754110 19593635 20668451 22722193 22722201 26960396 27245685 27284958 27535334 28027327 30062102 30181556 30531871 32723837 35657000 37336919 9331070 9622070	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MDM2	Unknown	28027327 30531871	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MDM4	Unknown	28027327	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MECOM	Unknown	22495314 22722201 27535334 28027327 30062102 31340200	Open Targets	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MEN1	Unknown	26373574 27135926 27284958 27535334 28027327 28481359 30062102 30205045 30350370	Open Targets	Cushing syndrome Transcriptional misregulation in cancer Formation of the beta-catenin:TCF transactivating complex +5 more
		MITF	Unknown	28027327	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLLT11	Unknown	28027327	Open Targets	—
		MRTFA	Unknown	28027327 20668451	Open Targets	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSI2	Unknown	22608084	Open Targets	mRNA surveillance pathway
		MTCP1	Unknown	20668451 22722193	Open Targets	PI3K-Akt signaling pathway
		MTOR	Unknown	18186519 20668451 22495314 22722193 26960396 27279227 27535334 28027327 29349598 29807833 30062102 30181556 31340200 33942253 35657000 37336919	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC1	Unknown	28027327 20668451	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +4 more
		MUTYH	Unknown	28027327 26960396	Open Targets	Base excision repair Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine +2 more
		MYB	Unknown	22722201 27535334 28027327 30531871	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYH9	Unknown	22495314 22722193 22722201 23856246 27535334 28027327 30062102	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +8 more
		MYOD1	Unknown	28027327	Open Targets	Spinocerebellar ataxia Myogenesis
		NACA	Unknown	28027327	Open Targets	Parathyroid hormone synthesis, secretion and action
		NBEA	Unknown	22495314 27245685 28027327 28153863 30350370 33021035	Open Targets	—
		NBN	Unknown	22722193 28027327 28481359	Open Targets	Homologous recombination Cellular senescence DNA Damage/Telomere Stress Induced Senescence +13 more
		NCKIPSD	Unknown	28027327	Open Targets	Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis
		NDRG1	Unknown	27535334 28027327	Open Targets	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
		NFATC2	Unknown	28027327 22495314	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Efferocytosis +24 more
		NFE2L2	Unknown	22722193 27284958 28027327 28481359 29349598	Open Targets	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NFKBIE	Unknown	35657000	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation T cell receptor signaling pathway +6 more
		NIN	Unknown	22608084 22722193 28027327 28153863 29214215	Open Targets	—
		NKX2-1	Unknown	28027327 37336919	Open Targets	—
		NOTCH2	Unknown	22722201 27284958 27535334 27566247 28027327 28481359 29349598 29807833 30062102 30205045 31340200 33942253	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NR2F2	Unknown	27535334 28027327	Open Targets	—
		NRAS	Unknown	17314276 19593635 20604919 22495314 24318467 29202330	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +130 more
		NSD1	Unknown	22495314 22722193 22722202 27535334 28027327 28153863 28481359 30062102 30205045 31340200	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NTHL1	Unknown	22495314	Open Targets	Base excision repair Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine +3 more
		NUMA1	Unknown	27535334 28027327	Open Targets	Recruitment of NuMA to mitotic centrosomes Mitotic Prophase
		NUTM1	Unknown	22495314 27535334 28027327	Open Targets	—
		OLIG2	Unknown	22495314	Open Targets	—
		PALB2	Unknown	26960396 27535334 28027327 28481359 30205045 30531871 31340200 37336919	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Homologous Recombination (HRR) +3 more
		PATZ1	Unknown	28027327	Open Targets	—
		PBX1	Unknown	28027327 30350370	Open Targets	Efferocytosis Cortisol synthesis and secretion Cushing syndrome +3 more
		PDCD1LG2	Unknown	28027327	Open Targets	Cell adhesion molecules PD-1 signaling
		PDGFRA	Unknown	22538770 22722193 22722201 22722202 23856246 26968814 28481359 29202330 29349598 29807833 30181556 30531871 35657000 37336919	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
		PDGFRB	Unknown	20668451 27535334 28027327 30062102 31340200 35657000	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +22 more
		PIK3R2	Unknown	28027327 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +129 more
		PLAG1	Unknown	20668451 22495314 27535334 28027327	Open Targets	—
		PMS2	Unknown	22495314 29349598 37336919	Open Targets	Mismatch repair Fanconi anemia pathway Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) +3 more
		POLR2A	Unknown	27535334 28027327	Open Targets	RNA polymerase Nucleotide excision repair Huntington disease +25 more
		PPARG	Unknown	27535334 28027327	Open Targets	PPAR signaling pathway Efferocytosis AMPK signaling pathway +13 more
		PPFIBP1	Unknown	28027327	Open Targets	Receptor-type tyrosine-protein phosphatases
		PPP2R1A	Unknown	10713707 22722201 27535334 28027327 29349598	Open Targets	mRNA surveillance pathway Sphingolipid signaling pathway Cell cycle +52 more
		PPP6C	Unknown	28027327	Open Targets	COPII-mediated vesicle transport
		PRDM16	Unknown	22495314 22722201	Open Targets	Lysine degradation Metabolic pathways Thermogenesis +1 more
		PRDM2	Unknown	26907767 27245685 27535334 28027327 31340200	Open Targets	Lysine degradation Metabolic pathways

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Female breast carcinoma

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