Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
FATTY LIVER	C0015695 MESH:D005234	ADRB2	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +13 more
		AKT1	Unknown	32045588	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		ANGPTL4	Unknown	28842503	CTD, Disgenet	PPAR signaling pathway Cholesterol metabolism PPARA activates gene expression +2 more
		APOB	Unknown	12048068 17303181	CTD, Disgenet	Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism +20 more
		APOE	Unknown	32853627	CTD, Disgenet	Cholesterol metabolism Alzheimer disease Nuclear signaling by ERBB4 +10 more
		ATF4	Unknown	27664470	CTD, Disgenet	MAPK signaling pathway cGMP-PKG signaling pathway Mitophagy - animal +41 more
		ATP5IF1	Unknown	25226513	CTD, Disgenet	—
		ATP7B	Unknown	17303181	CTD, Disgenet	Platinum drug resistance Mineral absorption Ion transport by P-type ATPases
		BIRC3	Unknown	21664615	CTD, Disgenet	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
		CA3	Unknown	—	Disgenet	Nitrogen metabolism Metabolic pathways Reversible hydration of carbon dioxide
		CAT	Unknown	10860543	CTD, Disgenet	Tryptophan metabolism Glyoxylate and dicarboxylate metabolism Metabolic pathways +11 more
		CCL2	Unknown	29684222	CTD, Disgenet	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +18 more
		CEBPB	Unknown	24469900	CTD, Disgenet	Efferocytosis IL-17 signaling pathway TNF signaling pathway +7 more
		CNDP2	Unknown	25226513	CTD, Disgenet	Arginine and proline metabolism Histidine metabolism beta-Alanine metabolism +2 more
		COL3A1	Unknown	15787813	CTD, Disgenet	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CXCL8	Unknown	23348005	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +37 more
		CYCS	Unknown	10860543	CTD, Disgenet	Oxidative phosphorylation Metabolic pathways Platinum drug resistance +39 more
		CYP19A1	Unknown	11929713	CTD, Disgenet	Steroid hormone biosynthesis Metabolic pathways Ovarian steroidogenesis +3 more
		CYP1B1	Unknown	27036855	CTD, Disgenet	Steroid hormone biosynthesis Tryptophan metabolism Metabolism of xenobiotics by cytochrome P450 +9 more
		CYP2E1	Unknown	18952117	CTD, Disgenet	Steroid hormone biosynthesis Arachidonic acid metabolism Linoleic acid metabolism +11 more
		CYP7B1	Unknown	23391614	CTD, Disgenet	Primary bile acid biosynthesis Steroid hormone biosynthesis Synthesis of bile acids and bile salts +4 more
		DDIT3	Unknown	27664470	CTD, Disgenet	MAPK signaling pathway Protein processing in endoplasmic reticulum Apoptosis +9 more
		DHRS7	Unknown	25226513	CTD, Disgenet	—
		F2	Unknown	20008134	CTD, Disgenet	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Complement and coagulation cascades +17 more
		F2R	Unknown	20008134 21907177 22841818	CTD, Disgenet	Rap1 signaling pathway Calcium signaling pathway cAMP signaling pathway +12 more
		FGF21	Unknown	24184811	CTD, Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +9 more
		FOXA1	Unknown	24469900	CTD, Disgenet	Estrogen-dependent gene expression
		GPD1L	Unknown	25226513	CTD, Disgenet	Glycerophospholipid metabolism Synthesis of PA
		GPT	Unknown	19481104	CTD, Disgenet	Arginine biosynthesis Alanine, aspartate and glutamate metabolism Metabolic pathways +4 more
		GPX1	Unknown	10860543	CTD, Disgenet	Glutathione metabolism Metabolic pathways Thyroid hormone synthesis +7 more
		GPX4	Unknown	26042203	CTD, Disgenet	Glutathione metabolism Arachidonic acid metabolism Metabolic pathways +7 more
		HADHA	Unknown	—	Disgenet	Fatty acid elongation Fatty acid degradation Valine, leucine and isoleucine degradation +15 more
		HADHB	Unknown	17116638	CTD, Disgenet	Fatty acid elongation Fatty acid degradation Valine, leucine and isoleucine degradation +10 more
		HAS3	Unknown	27042213	CTD, Disgenet	Hyaluronan biosynthesis and export
		HHEX	Unknown	24469900	CTD, Disgenet	Maturity onset diabetes of the young Transcriptional misregulation in cancer
		HTR2A	Unknown	—	Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction +4 more
		HTR2B	Unknown	—	Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction +4 more
		IFNA2	Unknown	31299271 7736406	CTD	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway Necroptosis +26 more
		INS	Unknown	9048448	CTD, Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +39 more
		LDLR	Unknown	25554529 36108984	CTD, Disgenet	Virion - Hepatitis viruses Endocytosis Ovarian steroidogenesis +12 more
		LEP	Unknown	12661780 19716478 24525044 25554529 27071101 27712037	CTD, Disgenet	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +7 more
		LEPR	Unknown	25367288 29743445 39059604	CTD, Disgenet	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +4 more
		MAT1A	Unknown	12060674	CTD, Disgenet	Cysteine and methionine metabolism One carbon pool by folate Metabolic pathways +6 more
		MET	Unknown	32045588	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		METTL3	Unknown	37236586	CTD	Processing of Capped Intron-Containing Pre-mRNA
		MTHFR	Unknown	—	Disgenet	One carbon pool by folate Metabolic pathways Antifolate resistance +2 more
		MTTP	Unknown	17303181	CTD, Disgenet	Fat digestion and absorption VLDL assembly Chylomicron assembly
		MYC	Unknown	24210820	CTD, Disgenet	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more
		NEIL1	Unknown	16446448 21285402	CTD, Disgenet	Base excision repair Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine +2 more
		NFE2L2	Unknown	28555106	CTD, Disgenet	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more

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Fatty liver

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