Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
FATTY LIVER	C0015695 MESH:D005234	ADRB2	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +13 more
FATTY LIVER	C0015695 MESH:D005234	AKT1	Unknown	32045588	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
FATTY LIVER	C0015695 MESH:D005234	ANGPTL4	Unknown	28842503	CTD, Disgenet	PPAR signaling pathway Cholesterol metabolism PPARA activates gene expression +2 more
FATTY LIVER	C0015695 MESH:D005234	APOB	Unknown	12048068 17303181	CTD, Disgenet	Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism +20 more
FATTY LIVER	C0015695 MESH:D005234	APOE	Unknown	32853627	CTD, Disgenet	Cholesterol metabolism Alzheimer disease Nuclear signaling by ERBB4 +10 more
FATTY LIVER	C0015695 MESH:D005234	ATF4	Unknown	27664470	CTD, Disgenet	MAPK signaling pathway cGMP-PKG signaling pathway Mitophagy - animal +41 more
FATTY LIVER	C0015695 MESH:D005234	ATP5IF1	Unknown	25226513	CTD, Disgenet	—
FATTY LIVER	C0015695 MESH:D005234	ATP7B	Unknown	17303181	CTD, Disgenet	Platinum drug resistance Mineral absorption Ion transport by P-type ATPases
FATTY LIVER	C0015695 MESH:D005234	BIRC3	Unknown	21664615	CTD, Disgenet	Platinum drug resistance NF-kappa B signaling pathway Ubiquitin mediated proteolysis +23 more
FATTY LIVER	C0015695 MESH:D005234	CA3	Unknown	—	Disgenet	Nitrogen metabolism Metabolic pathways Reversible hydration of carbon dioxide
FATTY LIVER	C0015695 MESH:D005234	CAT	Unknown	10860543	CTD, Disgenet	Tryptophan metabolism Glyoxylate and dicarboxylate metabolism Metabolic pathways +11 more
FATTY LIVER	C0015695 MESH:D005234	CCL2	Unknown	29684222	CTD, Disgenet	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +18 more
FATTY LIVER	C0015695 MESH:D005234	CEBPB	Unknown	24469900	CTD, Disgenet	Efferocytosis IL-17 signaling pathway TNF signaling pathway +7 more
FATTY LIVER	C0015695 MESH:D005234	CNDP2	Unknown	25226513	CTD, Disgenet	Arginine and proline metabolism Histidine metabolism beta-Alanine metabolism +2 more
FATTY LIVER	C0015695 MESH:D005234	COL3A1	Unknown	15787813	CTD, Disgenet	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
FATTY LIVER	C0015695 MESH:D005234	CXCL8	Unknown	23348005	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway +37 more
FATTY LIVER	C0015695 MESH:D005234	CYCS	Unknown	10860543	CTD, Disgenet	Oxidative phosphorylation Metabolic pathways Platinum drug resistance +39 more
FATTY LIVER	C0015695 MESH:D005234	CYP19A1	Unknown	11929713	CTD, Disgenet	Steroid hormone biosynthesis Metabolic pathways Ovarian steroidogenesis +3 more
FATTY LIVER	C0015695 MESH:D005234	CYP1B1	Unknown	27036855	CTD, Disgenet	Steroid hormone biosynthesis Tryptophan metabolism Metabolism of xenobiotics by cytochrome P450 +9 more
FATTY LIVER	C0015695 MESH:D005234	CYP2E1	Unknown	18952117	CTD, Disgenet	Steroid hormone biosynthesis Arachidonic acid metabolism Linoleic acid metabolism +11 more
FATTY LIVER	C0015695 MESH:D005234	CYP7B1	Unknown	23391614	CTD, Disgenet	Primary bile acid biosynthesis Steroid hormone biosynthesis Synthesis of bile acids and bile salts +4 more
FATTY LIVER	C0015695 MESH:D005234	DDIT3	Unknown	27664470	CTD, Disgenet	MAPK signaling pathway Protein processing in endoplasmic reticulum Apoptosis +9 more
FATTY LIVER	C0015695 MESH:D005234	DHRS7	Unknown	25226513	CTD, Disgenet	—
FATTY LIVER	C0015695 MESH:D005234	F2	Unknown	20008134	CTD, Disgenet	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Complement and coagulation cascades +17 more
FATTY LIVER	C0015695 MESH:D005234	F2R	Unknown	20008134 21907177 22841818	CTD, Disgenet	Rap1 signaling pathway Calcium signaling pathway cAMP signaling pathway +12 more
FATTY LIVER	C0015695 MESH:D005234	FGF21	Unknown	24184811	CTD, Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +9 more
FATTY LIVER	C0015695 MESH:D005234	FOXA1	Unknown	24469900	CTD, Disgenet	Estrogen-dependent gene expression
FATTY LIVER	C0015695 MESH:D005234	GPD1L	Unknown	25226513	CTD, Disgenet	Glycerophospholipid metabolism Synthesis of PA
FATTY LIVER	C0015695 MESH:D005234	GPT	Unknown	19481104	CTD, Disgenet	Arginine biosynthesis Alanine, aspartate and glutamate metabolism Metabolic pathways +4 more
FATTY LIVER	C0015695 MESH:D005234	GPX1	Unknown	10860543	CTD, Disgenet	Glutathione metabolism Metabolic pathways Thyroid hormone synthesis +7 more
FATTY LIVER	C0015695 MESH:D005234	GPX4	Unknown	26042203	CTD, Disgenet	Glutathione metabolism Arachidonic acid metabolism Metabolic pathways +7 more
FATTY LIVER	C0015695 MESH:D005234	HADHA	Unknown	—	Disgenet	Fatty acid elongation Fatty acid degradation Valine, leucine and isoleucine degradation +15 more
FATTY LIVER	C0015695 MESH:D005234	HADHB	Unknown	17116638	CTD, Disgenet	Fatty acid elongation Fatty acid degradation Valine, leucine and isoleucine degradation +10 more
FATTY LIVER	C0015695 MESH:D005234	HAS3	Unknown	27042213	CTD, Disgenet	Hyaluronan biosynthesis and export
FATTY LIVER	C0015695 MESH:D005234	HHEX	Unknown	24469900	CTD, Disgenet	Maturity onset diabetes of the young Transcriptional misregulation in cancer
FATTY LIVER	C0015695 MESH:D005234	HTR2A	Unknown	—	Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction +4 more
FATTY LIVER	C0015695 MESH:D005234	HTR2B	Unknown	—	Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction +4 more
FATTY LIVER	C0015695 MESH:D005234	IFNA2	Unknown	31299271 7736406	CTD	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway Necroptosis +26 more
FATTY LIVER	C0015695 MESH:D005234	INS	Unknown	9048448	CTD, Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +39 more
FATTY LIVER	C0015695 MESH:D005234	LDLR	Unknown	25554529 36108984	CTD, Disgenet	Virion - Hepatitis viruses Endocytosis Ovarian steroidogenesis +12 more
FATTY LIVER	C0015695 MESH:D005234	LEP	Unknown	12661780 19716478 24525044 25554529 27071101 27712037	CTD, Disgenet	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +7 more
FATTY LIVER	C0015695 MESH:D005234	LEPR	Unknown	25367288 29743445 39059604	CTD, Disgenet	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +4 more
FATTY LIVER	C0015695 MESH:D005234	MAT1A	Unknown	12060674	CTD, Disgenet	Cysteine and methionine metabolism One carbon pool by folate Metabolic pathways +6 more
FATTY LIVER	C0015695 MESH:D005234	MET	Unknown	32045588	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
FATTY LIVER	C0015695 MESH:D005234	METTL3	Unknown	37236586	CTD	Processing of Capped Intron-Containing Pre-mRNA
FATTY LIVER	C0015695 MESH:D005234	MTHFR	Unknown	—	Disgenet	One carbon pool by folate Metabolic pathways Antifolate resistance +2 more
FATTY LIVER	C0015695 MESH:D005234	MTTP	Unknown	17303181	CTD, Disgenet	Fat digestion and absorption VLDL assembly Chylomicron assembly
FATTY LIVER	C0015695 MESH:D005234	MYC	Unknown	24210820	CTD, Disgenet	MAPK signaling pathway ErbB signaling pathway Cell cycle +45 more
FATTY LIVER	C0015695 MESH:D005234	NEIL1	Unknown	16446448 21285402	CTD, Disgenet	Base excision repair Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine +2 more
FATTY LIVER	C0015695 MESH:D005234	NFE2L2	Unknown	28555106	CTD, Disgenet	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more

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Fatty liver

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