Epilepsy

Antigen processing: Ubiquitination & Proteasome degradation

Taste transduction Phase 0 - rapid depolarisation

Protein processing in endoplasmic reticulum Pathogenic Escherichia coli infection COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC +3 more

Salivary secretion Pancreatic secretion Vibrio cholerae infection Cation-coupled Chloride cotransporters +1 more

GABAergic synapse Cation-coupled Chloride cotransporters

Synaptic vesicle cycle Glutamatergic synapse Protein digestion and absorption Glutamate Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) +3 more

Synaptic vesicle cycle Glutamatergic synapse Amyotrophic lateral sclerosis Huntington disease Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides +4 more

Synaptic vesicle cycle Glutamatergic synapse Huntington disease Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides Defective SLC1A3 causes episodic ataxia 6 (EA6) +4 more

Bicarbonate transporters

Synaptic vesicle cycle GABAergic synapse Na+/Cl- dependent neurotransmitter transporters Reuptake of GABA +1 more

Cell adhesion molecules Receptor-type tyrosine-protein phosphatases

Cell cycle Oocyte meiosis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression +5 more

Synaptic vesicle cycle Insulin secretion Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Other interleukin signaling Toxicity of botulinum toxin type A (BoNT/A) Toxicity of botulinum toxin type C (BoNT/C) Toxicity of botulinum toxin type E (BoNT/E) Neutrophil degranulation GABA synthesis, release, reuptake and degradation +10 more

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation

Endocytosis Metalloprotease DUBs

mTOR signaling pathway AMPK signaling pathway Energy dependent regulation of mTOR by LKB1-AMPK

SNARE interactions in vesicular transport Synaptic vesicle cycle Toxicity of botulinum toxin type C (BoNT/C) LGI-ADAM interactions +1 more

Synaptic vesicle cycle Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +4 more

ECM-receptor interaction Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type A (BoNT/A) Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type E (BoNT/E) +2 more

Ras signaling pathway Regulation of RAS by GAPs

Toxicity of botulinum toxin type B (BoNT/B) Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis

MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway Cell cycle Efferocytosis Cellular senescence TGF-beta signaling pathway Osteoclast differentiation Hippo signaling pathway Th17 cell differentiation Intestinal immune network for IgA production Relaxin signaling pathway Non-alcoholic fatty liver disease AGE-RAGE signaling pathway in diabetic complications Leishmaniasis Chagas disease Malaria Toxoplasmosis Amoebiasis Tuberculosis Hepatitis B Human T-cell leukemia virus 1 infection Pathways in cancer Proteoglycans in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hepatocellular carcinoma Gastric cancer Inflammatory bowel disease Rheumatoid arthritis Hypertrophic cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Platelet degranulation Influenza Virus Induced Apoptosis Cell surface interactions at the vascular wall Molecules associated with elastic fibres Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Syndecan interactions SMAD2/3 Phosphorylation Motif Mutants in Cancer TGFBR2 MSI Frameshift Mutants in Cancer TGFBR2 Kinase Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Interleukin-4 and Interleukin-13 signaling RUNX3 regulates CDKN1A transcription Regulation of RUNX3 expression and activity RUNX3 regulates p14-ARF +49 more

TCF dependent signaling in response to WNT Degradation of AXIN XAV939 inhibits tankyrase, stabilizing AXIN Ub-specific processing proteases Regulation of PTEN stability and activity +2 more

Antigen processing: Ubiquitination & Proteasome degradation

Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Longevity regulating pathway Cellular senescence Thermogenesis Insulin signaling pathway Human cytomegalovirus infection Human papillomavirus infection Herpes simplex virus 1 infection Choline metabolism in cancer Macroautophagy Inhibition of TSC complex formation by PKB Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes TBC/RABGAPs +15 more

Phospholipase D signaling pathway p53 signaling pathway Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Longevity regulating pathway Cellular senescence Thermogenesis Insulin signaling pathway Thyroid hormone signaling pathway Human cytomegalovirus infection Human papillomavirus infection Herpes simplex virus 1 infection Choline metabolism in cancer Macroautophagy Inhibition of TSC complex formation by PKB AKT phosphorylates targets in the cytosol Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Constitutive Signaling by AKT1 E17K in Cancer TBC/RABGAPs +19 more

cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling Thyroid hormone synthesis Regulation of lipolysis in adipocytes Autoimmune thyroid disease Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production +6 more

Hedgehog 'off' state Intraflagellar transport

Selenocompound metabolism Pathways in cancer Hepatocellular carcinoma PPARA activates gene expression Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates Metabolism of ingested MeSeO2H into MeSeH Uptake and function of diphtheria toxin TP53 Regulates Metabolic Genes +6 more

Ubiquitin mediated proteolysis Human papillomavirus infection Viral carcinogenesis Antigen processing: Ubiquitination & Proteasome degradation +1 more

Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Steroid hormone biosynthesis Retinol metabolism Porphyrin metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways Biosynthesis of cofactors Bile secretion Chemical carcinogenesis - DNA adducts Chemical carcinogenesis - receptor activation Glucuronidation +11 more

Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Steroid hormone biosynthesis Retinol metabolism Porphyrin metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways Biosynthesis of cofactors Bile secretion Chemical carcinogenesis - DNA adducts Chemical carcinogenesis - receptor activation Glucuronidation +11 more

IL-17 signaling pathway Ub-specific processing proteases

Calcium signaling pathway cGMP-PKG signaling pathway Necroptosis Cellular senescence Neutrophil extracellular trap formation NOD-like receptor signaling pathway Cholesterol metabolism Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Spinocerebellar ataxia Prion disease Pathways of neurodegeneration - multiple diseases Shigellosis Influenza A Human T-cell leukemia virus 1 infection Chemical carcinogenesis - reactive oxygen species Diabetic cardiomyopathy Pink/Parkin Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism +19 more

Calcium signaling pathway cGMP-PKG signaling pathway Ferroptosis Necroptosis Cellular senescence Neutrophil extracellular trap formation NOD-like receptor signaling pathway Cholesterol metabolism Alzheimer disease Parkinson disease Huntington disease Spinocerebellar ataxia Prion disease Pathways of neurodegeneration - multiple diseases Human T-cell leukemia virus 1 infection Chemical carcinogenesis - reactive oxygen species Diabetic cardiomyopathy Ub-specific processing proteases +15 more

Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation

Autophagy - animal Macroautophagy

Nuclear signaling by ERBB4 Negative regulation of activity of TFAP2 (AP-2) family transcription factors Activation of the TFAP2 (AP-2) family of transcription factors

Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription

GABAergic synapse Cation-coupled Chloride cotransporters