Endometrial serous adenocarcinoma | Gene-Disease Associations & Pathways | GeDiPNet

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Subtype of: Endometrial cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
endometrial serous adenocarcinoma	MONDO_0006196	PIK3R1	Unknown	33536036 30908539 21478295	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +150 more
		PLAG1	Unknown	23104009	Open Targets	—
		POLE	Unknown	38571325 32457342 27894751 26763250 23104009 29420467	Open Targets	DNA replication Base excision repair Nucleotide excision repair +10 more
		PPFIBP1	Unknown	23104009	Open Targets	Receptor-type tyrosine-protein phosphatases
		PPP2R1A	Unknown	21381030 22923510 25720322 30710169 22653804 21882256 23104009 21435433	Open Targets	mRNA surveillance pathway Sphingolipid signaling pathway Cell cycle +52 more
		PTEN	Unknown	21266528 30908539 26975040 33536036 22498935 9829719	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		PTPRB	Unknown	23104009	Open Targets	Adherens junction Neutrophil degranulation
		RANBP2	Unknown	28945609	Open Targets	Nucleocytoplasmic transport Viral life cycle - HIV-1 Amyotrophic lateral sclerosis +32 more
		RASA1	Unknown	23104009 22923510	Open Targets	MAPK signaling pathway Ras signaling pathway Axon guidance +5 more
		RB1	Unknown	28945609	Open Targets	Endocrine resistance Cell cycle Cellular senescence +30 more
		RECQL4	Unknown	23104009	Open Targets	—
		RGPD3	Unknown	23104009	Open Targets	—
		RICTOR	Unknown	23104009	Open Targets	mTOR signaling pathway PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling +3 more
		RRAS2	Unknown	23104009	Open Targets	MAPK signaling pathway Ras signaling pathway cAMP signaling pathway +8 more
		RXRA	Unknown	23104009	Open Targets	PPAR signaling pathway Efferocytosis PI3K-Akt signaling pathway +39 more
		SHTN1	Unknown	23104009	Open Targets	—
		SLC34A2	Unknown	22923510	Open Targets	Parathyroid hormone synthesis, secretion and action Mineral absorption Type II Na+/Pi cotransporters +2 more
		SND1	Unknown	23104009	Open Targets	Viral carcinogenesis Signaling by BRAF and RAF fusions
		SPOP	Unknown	23104009 22923510	Open Targets	Hedgehog signaling pathway Hedgehog 'on' state
		STAG2	Unknown	23104009	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STIL	Unknown	23104009	Open Targets	—
		TBL1XR1	Unknown	23104009	Open Targets	Wnt signaling pathway RORA activates gene expression PPARA activates gene expression +11 more
		TBX3	Unknown	23104009	Open Targets	Signaling pathways regulating pluripotency of stem cells
		TOP1	Unknown	23104009	Open Targets	SUMOylation of DNA replication proteins
		TP53	Unknown	12144684 7743473 33919505 25550841 22923510 1333465 30908539 35949786 28945609 30710169 33536036 9635683 22653804 23104009 29420467 36238840	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TRAF7	Unknown	22923510	Open Targets	Antigen processing: Ubiquitination & Proteasome degradation
		TRRAP	Unknown	23104009	Open Targets	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection Formation of the beta-catenin:TCF transactivating complex +1 more
		UBR5	Unknown	23104009	Open Targets	Ubiquitin mediated proteolysis
		USP6	Unknown	22923510	Open Targets	—
		XPO1	Unknown	23104009	Open Targets	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more

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