Subtype of: Endometrial cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
endometrial endometrioid adenocarcinoma	MONDO_0006192	KDM5C	Unknown	36142641 33016334 28481359	Open Targets	HDMs demethylate histones
		KDM6A	Unknown	37328769 33016334 28481359 32909971	Open Targets	Transcriptional misregulation in cancer HDMs demethylate histones
		KDR	Unknown	28481359 36713525 30886832 27159395	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +13 more
		KEAP1	Unknown	28481359 33016334 30908539 21897267 35953603	Open Targets	Ubiquitin mediated proteolysis Parkinson disease Pathways in cancer +6 more
		KIAA1549	Unknown	33016334	Open Targets	Signaling by BRAF and RAF fusions
		KIF5B	Unknown	19383809	Open Targets	Endocytosis Dopaminergic synapse Motor proteins +12 more
		KIT	Unknown	28481359 36713525 29876005 23199529 27159395	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KLF4	Unknown	28481359	Open Targets	Signaling pathways regulating pluripotency of stem cells Chemical carcinogenesis - receptor activation Synthesis, secretion, and deacylation of Ghrelin +1 more
		KLF6	Unknown	33016334	Open Targets	—
		KMT2A	Unknown	37328769 33016334 28481359	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2C	Unknown	28485815 33016334 28481359 27159395	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	35953603 27159395 27566247 29420467 32909971 37328769 33016334 28481359	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KRAS	Unknown	20062086 8137266 21266528 7960232 1581890 24071873 25624430 11179836 27302833 16619251 21726664 7856726 18084252 35953603 11180166 30710169 22653804 9421075 18500270 22271473 11553860 29876005 36238840 24651628 18757403 21470976 18425390 24561032 22662154 30908539 22498935 8467512 16256179 19839777 36765365 23733133 12015762 18980800 23674493 28485815 23370429 1913654 23199529 1442931 29162652 36142641 19424571 33016334 28481359 23851676	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LARP4B	Unknown	33016334	Open Targets	—
		LATS1	Unknown	28481359	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LATS2	Unknown	28481359	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo
		LIFR	Unknown	33016334	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LMO1	Unknown	28481359	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs
		LOC100506403	Unknown	28481359	Open Targets	—
		LOC105376156	Unknown	28481359	Open Targets	—
		LOC124905021	Unknown	28481359	Open Targets	—
		LRIG3	Unknown	33016334	Open Targets	—
		LRP1B	Unknown	33016334 27159395	Open Targets	—
		LYL1	Unknown	33016334	Open Targets	Transcriptional misregulation in cancer NGF-stimulated transcription
		LYN	Unknown	33016334	Open Targets	Chemokine signaling pathway NF-kappa B signaling pathway Platelet activation +36 more
		LZTR1	Unknown	33016334	Open Targets	—
		MACC1	Unknown	33016334	Open Targets	—
		MALT1	Unknown	28481359	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		MAP2K1	Unknown	28481359 35953603 21726664 27159395	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP2K2	Unknown	36142641	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +87 more
		MAP2K4	Unknown	28481359	Open Targets	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway +21 more
		MAP3K1	Unknown	36142641 27566247 33016334 28481359 32909971	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K13	Unknown	28481359	Open Targets	MAPK signaling pathway
		MAPK1	Unknown	33016334 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +161 more
		MAX	Unknown	33016334 28481359 29155953	Open Targets	Polycomb repressive complex MAPK signaling pathway Pathways in cancer +6 more
		MDM2	Unknown	28481359	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MDM4	Unknown	28481359	Open Targets	p53 signaling pathway MicroRNAs in cancer Oxidative Stress Induced Senescence +6 more
		MED12	Unknown	33016334 28481359 27159395 32909971	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MEN1	Unknown	36142641 33016334 28481359	Open Targets	Cushing syndrome Transcriptional misregulation in cancer Formation of the beta-catenin:TCF transactivating complex +5 more
		MET	Unknown	30886885 29876005 33016334 28481359 27159395	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MITF	Unknown	28481359	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLH1	Unknown	27302833 33016334 28481359 27159395 35953603	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MLLT10	Unknown	33016334	Open Targets	—
		MN1	Unknown	33016334	Open Targets	—
		MPL	Unknown	33016334 28481359	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling JAK-STAT signaling pathway
		MRTFA	Unknown	33016334	Open Targets	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH2	Unknown	27302833 37328769 37298034 28481359 25194673	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MSH6	Unknown	27159395 25194673 37298034 27302833 36765365 29876005 33016334 28481359	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		MSN	Unknown	33016334	Open Targets	Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton +4 more
		MTOR	Unknown	30886885 33016334 28481359 37298034	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more

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Endometrial endometrioid adenocarcinoma

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