Subtype of: Endometrial cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
endometrial endometrioid adenocarcinoma	MONDO_0006192	CTNNA2	Unknown	33016334	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNNB1	Unknown	12439748 16021566 9721853 11048799 11329142 27159395 11957146 19085831 25624430 12708483 21726664 18552176 18084252 35953603 28103826 30710169 36713525 22635024 10076565 18500270 22653804 29876005 10671680 36238840 21470976 12015762 10416591 11161379 24633194 32909971 11385321 37328769 33016334 28481359	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND2	Unknown	33016334	Open Targets	Wnt signaling pathway
		CUL3	Unknown	33016334 28481359	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		CUX1	Unknown	33016334	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		DAXX	Unknown	28481359	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more
		DCAF12L2	Unknown	33016334	Open Targets	—
		DCC	Unknown	29162652	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DDIT3	Unknown	33016334	Open Targets	MAPK signaling pathway Protein processing in endoplasmic reticulum Apoptosis +9 more
		DDR2	Unknown	28481359	Open Targets	Non-integrin membrane-ECM interactions
		DDX10	Unknown	29162652	Open Targets	—
		DDX3X	Unknown	33016334	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		DEK	Unknown	33016334	Open Targets	B-WICH complex positively regulates rRNA expression Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Transcriptional regulation of granulopoiesis
		DICER1	Unknown	33016334 28481359 27159395	Open Targets	MicroRNAs in cancer MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
		DNAJB1	Unknown	28481359	Open Targets	Protein processing in endoplasmic reticulum Influenza A Regulation of HSF1-mediated heat shock response +4 more
		DNM2	Unknown	33016334	Open Targets	Phospholipase D signaling pathway Endocytosis Fc gamma R-mediated phagocytosis +13 more
		DNMT3A	Unknown	28481359	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		DROSHA	Unknown	33016334	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis
		EED	Unknown	28481359	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +4 more
		EGFR	Unknown	23674493 28481359 29876005 23199529 35953603	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EIF1AX	Unknown	28481359	Open Targets	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits +3 more
		EIF4A2	Unknown	28481359	Open Targets	ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA +4 more
		ELL	Unknown	33016334	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +4 more
		ELN	Unknown	33016334	Open Targets	Cytoskeleton in muscle cells Protein digestion and absorption Degradation of the extracellular matrix +2 more
		EP300	Unknown	27159395 30710169 36142641 27566247 33016334 28481359	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		EPHA3	Unknown	33016334 28481359	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		EPHA7	Unknown	28481359	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		ERBB2	Unknown	29420467 28481359 35953603	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB3	Unknown	33016334 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERBB4	Unknown	36142641 33016334 28481359	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERCC2	Unknown	33016334 28481359	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC3	Unknown	33016334 28481359	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC4	Unknown	33016334 28481359	Open Targets	Nucleotide excision repair Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +4 more
		ERCC5	Unknown	37328769 28481359	Open Targets	Nucleotide excision repair Formation of Incision Complex in GG-NER Dual Incision in GG-NER +1 more
		ERG	Unknown	33016334 28481359	Open Targets	Transcriptional misregulation in cancer Prostate cancer
		ESR1	Unknown	32909971 28481359 27159395 28103826	Open Targets	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		ETV1	Unknown	28481359	Open Targets	Transcriptional misregulation in cancer
		ETV4	Unknown	33016334	Open Targets	Transcriptional misregulation in cancer MAPK6/MAPK4 signaling
		ETV6	Unknown	33016334 28481359	Open Targets	Transcriptional misregulation in cancer Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
		EZH2	Unknown	33016334 28481359 27159395	Open Targets	Lysine degradation Metabolic pathways Polycomb repressive complex +7 more
		FADD	Unknown	33016334	Open Targets	Platinum drug resistance Apoptosis Apoptosis - multiple species +36 more
		FAM135B	Unknown	33016334	Open Targets	—
		FAM47C	Unknown	33016334	Open Targets	—
		FANCA	Unknown	28481359	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCD2	Unknown	29162652	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
		FAT1	Unknown	37328769 28481359 27159395 32909971	Open Targets	—
		FAT3	Unknown	33016334	Open Targets	—
		FAT4	Unknown	37328769 33016334	Open Targets	Hippo signaling pathway - multiple species
		FBXO11	Unknown	27159395 25194673 27302833 36765365 29876005 33016334 28481359	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	35953603 29876005 30710169 37298034 36142641 14648662 37328769 23104009 28481359 21726664	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more

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Endometrial endometrioid adenocarcinoma

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