Subtype of: Endometrial cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
endometrial clear cell adenocarcinoma	MONDO_0006191	PTEN	Unknown	28485815 23949151 21266528 30908539 33536036 19853286 22498935 11156411 27302833 28481359	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +37 more
		PTPRT	Unknown	28481359	Open Targets	—
		RAD50	Unknown	28485815	Open Targets	Homologous recombination Non-homologous end-joining Cellular senescence +14 more
		RASA1	Unknown	28485815 28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Axon guidance +5 more
		RICTOR	Unknown	28481359	Open Targets	mTOR signaling pathway PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling +3 more
		ROCK1	Unknown	28485815	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Chemokine signaling pathway +25 more
		ROS1	Unknown	28481359	Open Targets	—
		SETBP1	Unknown	28485815	Open Targets	—
		SETD2	Unknown	28481359	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SLC45A3	Unknown	28485815	Open Targets	Transcriptional misregulation in cancer MicroRNAs in cancer Cellular hexose transport
		SMAD2	Unknown	28481359	Open Targets	Cell cycle Endocytosis Cellular senescence +30 more
		SMAD3	Unknown	28481359	Open Targets	FoxO signaling pathway Cell cycle Endocytosis +34 more
		SMAD4	Unknown	28481359	Open Targets	FoxO signaling pathway Hormone signaling Cell cycle +30 more
		SMARCA4	Unknown	28485815 28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		SMO	Unknown	28481359	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SPEN	Unknown	28481359	Open Targets	Notch signaling pathway
		SPOP	Unknown	25308272 28485815 23104009 28481359	Open Targets	Hedgehog signaling pathway Hedgehog 'on' state
		SRSF3	Unknown	28485815	Open Targets	Spliceosome Amyotrophic lateral sclerosis Herpes simplex virus 1 infection +4 more
		STK11	Unknown	28481359	Open Targets	FoxO signaling pathway Hormone signaling Autophagy - animal +9 more
		TCF7L2	Unknown	28481359	Open Targets	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TENT5C	Unknown	28481359	Open Targets	—
		TERT	Unknown	28485815 28481359	Open Targets	Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer +4 more
		TET2	Unknown	28485815 28481359	Open Targets	—
		TGFBR2	Unknown	28485815	Open Targets	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TNFAIP3	Unknown	28481359	Open Targets	NF-kappa B signaling pathway Necroptosis NOD-like receptor signaling pathway +10 more
		TP53	Unknown	25308272 28485815 29420467 14976538 28481359	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TRAF7	Unknown	28485815	Open Targets	Antigen processing: Ubiquitination & Proteasome degradation
		TRIP11	Unknown	28485815	Open Targets	Intraflagellar transport Intra-Golgi traffic
		TSC2	Unknown	28481359	Open Targets	Phospholipase D signaling pathway p53 signaling pathway Autophagy - animal +19 more
		UBR5	Unknown	28485815	Open Targets	Ubiquitin mediated proteolysis
		USP44	Unknown	28485815	Open Targets	Ub-specific processing proteases
		USP6	Unknown	28485815	Open Targets	—
		XPO1	Unknown	28481359	Open Targets	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more
		YAP1	Unknown	28481359	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Nuclear signaling by ERBB4 +5 more
		ZBTB16	Unknown	28485815	Open Targets	Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia +2 more
		ZFHX3	Unknown	28485815 28481359	Open Targets	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription

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Endometrial clear cell adenocarcinoma

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