Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLORECTAL NEOPLASMS	MESH:D015179	ABCA1	Unknown	22294766	CTD	ABC transporters Efferocytosis Fat digestion and absorption +6 more
		ABCA10	Unknown	22294766	CTD	ABC transporters ABC transporters in lipid homeostasis
		ABCA12	Unknown	22294766	CTD	ABC transporters ABC transporters in lipid homeostasis Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B
		ABCA13	Unknown	22294766	CTD	ABC transporters Neutrophil degranulation
		ABCA3	Unknown	22294766	CTD	ABC transporters ABC transporters in lipid homeostasis Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3) +2 more
		ABCA4	Unknown	22294766	CTD	ABC transporters Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) +1 more
		ABCA5	Unknown	22294766	CTD	ABC transporters ABC transporters in lipid homeostasis
		ABCA6	Unknown	22294766	CTD	ABC transporters ABC transporters in lipid homeostasis FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
		ABCA8	Unknown	22294766	CTD	ABC transporters ABC-family proteins mediated transport
		ABCA9	Unknown	22294766	CTD	ABC transporters ABC transporters in lipid homeostasis
		ABCB1	Unknown	22294766 23977225	CTD	ABC transporters Bile secretion MicroRNAs in cancer +2 more
		ABCB10	Unknown	22294766	CTD	ABC transporters Mitochondrial ABC transporters
		ABCB11	Unknown	22294766	CTD	Endocrine resistance ABC transporters Bile secretion +4 more
		ABCB4	Unknown	22294766	CTD	ABC transporters Bile secretion PPARA activates gene expression +2 more
		ABCB5	Unknown	22294766	CTD	ABC transporters ABC-family proteins mediated transport
		ABCB6	Unknown	22294766	CTD	ABC transporters Mitochondrial ABC transporters Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)
		ABCC1	Unknown	22294766	CTD	Antifolate resistance ABC transporters Sphingolipid signaling pathway +7 more
		ABCC2	Unknown	22294766	CTD	Antifolate resistance Platinum drug resistance ABC transporters +5 more
		ABCC3	Unknown	22294766	CTD	Antifolate resistance ABC transporters Bile secretion +3 more
		ABCC4	Unknown	22294766	CTD	Antifolate resistance ABC transporters cAMP signaling pathway +4 more
		ABCC5	Unknown	22294766	CTD	Antifolate resistance ABC transporters Folate transport and metabolism +2 more
		ABCC6	Unknown	22294766	CTD	ABC transporters ABC-family proteins mediated transport Defective ABCC6 causes pseudoxanthoma elasticum (PXE)
		ABCC8	Unknown	22294766	CTD	ABC transporters Insulin secretion Type II diabetes mellitus +3 more
		ABCD2	Unknown	22294766	CTD	ABC transporters Peroxisome ABC transporters in lipid homeostasis +1 more
		ABCD3	Unknown	22294766	CTD	ABC transporters Peroxisome ABC transporters in lipid homeostasis +1 more
		ABCD4	Unknown	22294766	CTD	ABC transporters Peroxisome Vitamin digestion and absorption +3 more
		ABCE1	Unknown	22294766	CTD	OAS antiviral response Interferon alpha/beta signaling
		ABCG1	Unknown	22294766	CTD	ABC transporters Lipid and atherosclerosis ABC transporters in lipid homeostasis +2 more
		ABCG2	Unknown	21544799 22294766	CTD	Antifolate resistance ABC transporters Bile secretion +4 more
		ACHE	Unknown	31004929	CTD	Glycerophospholipid metabolism Cholinergic synapse Neurotransmitter clearance +2 more
		ACKR3	Unknown	22180778	CTD	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine receptors bind chemokines +1 more
		ADH1B	Unknown	16332725	CTD	Glycolysis / Gluconeogenesis Fatty acid degradation Tyrosine metabolism +7 more
		AKR1B10	Unknown	17597105	CTD	Pentose and glucuronate interconversions Fructose and mannose metabolism Galactose metabolism +4 more
		AKT1	Unknown	—	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		ALDH2	Unknown	16332725	CTD	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid degradation +14 more
		AMACR	Unknown	17684125	CTD	Primary bile acid biosynthesis Metabolic pathways Peroxisome +4 more
		ANP32A	Unknown	25944804	CTD	HuR (ELAVL1) binds and stabilizes mRNA
		APC	Unknown	12907644 17116713 18716850 19309276 21291235 21531761 21967605	CTD	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		APC2	Unknown	18507500 18716850 21278247	CTD	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +13 more
		ARID1A	Unknown	27941798	CTD	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARNT	Unknown	21081473	CTD	HIF-1 signaling pathway Efferocytosis Cushing syndrome +10 more
		ATOX1	Unknown	31961892	CTD	Mineral absorption Ion influx/efflux at host-pathogen interface
		ATP7B	Unknown	19296535	CTD	Platinum drug resistance Mineral absorption Ion transport by P-type ATPases
		AURKA	Unknown	24976383	CTD	Oocyte meiosis Progesterone-mediated oocyte maturation APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 +6 more
		AXIN2	Unknown	—	CTD	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +15 more
		BAX	Unknown	—	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +52 more
		BCL2	Unknown	18949393	CTD	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		BIRC5	Unknown	16364925	CTD	Platinum drug resistance Apoptosis Apoptosis - multiple species +15 more
		BMP2	Unknown	30510241	CTD	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway +5 more
		BMP4	Unknown	19011631	CTD	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway +8 more
COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS	MESH:D003123	APC	Unknown	7661930	CTD	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more

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Colorectal neoplasms

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