Cerebellar pilocytic astrocytoma | Gene-Disease Associations & Pathways | GeDiPNet

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Subtype of: Astrocytoma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
cerebellar pilocytic astrocytoma	MONDO_0003168	ARID1A	Unknown	37953905	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ATM	Unknown	37953905	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATRX	Unknown	23583981	Open Targets	Cell cycle
		BCORL1	Unknown	23583981	Open Targets	Polycomb repressive complex
		BRAF	Unknown	18974108 21424530 19016743 22548077 25066317 23612919 21190184 23817572 28468611 19373855 19543740 23082883 20068183 19363522 26083571 23442159 22710963	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		CDKN2A	Unknown	21113787	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CTNNA2	Unknown	23583981	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		FAM131B	Unknown	21424530 23817572	Open Targets	Signaling by BRAF and RAF fusions
		FGFR1	Unknown	26083571	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +32 more
		GPC5	Unknown	23583981	Open Targets	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation +7 more
		IDH1	Unknown	25295857	Open Targets	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +9 more
		IKZF1	Unknown	23583981	Open Targets	—
		KIAA1549	Unknown	18974108 21424530 19016743 22548077 23583981 23612919 23817572 28468611 19373855 19543740 20068183 22710963	Open Targets	Signaling by BRAF and RAF fusions
		KRAS	Unknown	21424530 21046410 19373855	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		LHFPL6	Unknown	23583981	Open Targets	—
		LRP1B	Unknown	23583981	Open Targets	—
		NF1	Unknown	23583981	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NRG1	Unknown	23583981	Open Targets	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more
		NTRK2	Unknown	23817572	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more
		POLE	Unknown	37953905	Open Targets	DNA replication Base excision repair Nucleotide excision repair +10 more
		PPFIBP1	Unknown	23583981	Open Targets	Receptor-type tyrosine-protein phosphatases
		PRDM16	Unknown	23583981	Open Targets	Lysine degradation Metabolic pathways Thermogenesis +1 more
		PTPRD	Unknown	23583981	Open Targets	Cell adhesion molecules Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
		QKI	Unknown	23817572	Open Targets	Signaling by BRAF and RAF fusions
		RAF1	Unknown	21424530 19363522 19373855	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +93 more
		ROBO2	Unknown	23583981	Open Targets	Axon guidance Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO
		SMAD2	Unknown	23583981	Open Targets	Cell cycle Endocytosis Cellular senescence +30 more
		SRGAP3	Unknown	21424530 19363522 19373855	Open Targets	Axon guidance Rho GTPase cycle
		TCF12	Unknown	23583981	Open Targets	Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription