Subtype of: Central nervous system cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
central nervous system primitive neuroectodermal neoplasm	MONDO_0000640	RPL5	Unknown	25642631	Open Targets	Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression +7 more
		RPN1	Unknown	25642631	Open Targets	N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways +2 more
		RSPO2	Unknown	25642631 22722829	Open Targets	Wnt signaling pathway Regulation of FZD by ubiquitination
		RUNX1T1	Unknown	25642631	Open Targets	Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia
		RXRA	Unknown	22722829	Open Targets	PPAR signaling pathway Efferocytosis PI3K-Akt signaling pathway +39 more
		SDHA	Unknown	25642631	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SDHC	Unknown	25642631	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SEPTIN9	Unknown	25642631 22722829	Open Targets	Bacterial invasion of epithelial cells Shigellosis
		SETBP1	Unknown	25642631 22722829	Open Targets	—
		SETD1B	Unknown	25642631	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		SETD2	Unknown	25642631 22820256 22832583	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SETDB1	Unknown	25642631	Open Targets	Lysine degradation Metabolic pathways Signaling pathways regulating pluripotency of stem cells +1 more
		SF3B1	Unknown	25642631 22722829	Open Targets	Spliceosome B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway +1 more
		SFPQ	Unknown	25642631	Open Targets	PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
		SGK1	Unknown	22722829	Open Targets	FoxO signaling pathway Efferocytosis mTOR signaling pathway +6 more
		SHTN1	Unknown	22722829	Open Targets	—
		SIRPA	Unknown	25642631 22722829	Open Targets	Efferocytosis Osteoclast differentiation Cell surface interactions at the vascular wall +2 more
		SIX1	Unknown	25642631	Open Targets	Transcriptional misregulation in cancer
		SLC34A2	Unknown	25642631	Open Targets	Parathyroid hormone synthesis, secretion and action Mineral absorption Type II Na+/Pi cotransporters +2 more
		SMAD2	Unknown	25642631 22722829	Open Targets	Cell cycle Endocytosis Cellular senescence +30 more
		SMAD3	Unknown	22820256 22722829	Open Targets	FoxO signaling pathway Cell cycle Endocytosis +34 more
		SMAD4	Unknown	22722829	Open Targets	FoxO signaling pathway Hormone signaling Cell cycle +30 more
		SMARCA4	Unknown	22820256 26822237 22722829 33020650 21163964 22832583	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		SMARCB1	Unknown	10914721 33020650 11972800 10556283 25642631 22832583	Open Targets	ATP-dependent chromatin remodeling Viral life cycle - HIV-1 Thermogenesis +3 more
		SMARCD1	Unknown	25642631	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SMC1A	Unknown	25642631 22832583	Open Targets	Cell cycle Oocyte meiosis Separation of Sister Chromatids +5 more
		SMO	Unknown	19726788 33020650 28481359 22820256	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SND1	Unknown	25642631	Open Targets	Viral carcinogenesis Signaling by BRAF and RAF fusions
		SNX29	Unknown	22722829	Open Targets	—
		SOX21	Unknown	25642631	Open Targets	—
		SPECC1	Unknown	25642631 22832583 22722829	Open Targets	—
		SPEN	Unknown	25642631 22820256	Open Targets	Notch signaling pathway
		SPOP	Unknown	25642631	Open Targets	Hedgehog signaling pathway Hedgehog 'on' state
		SRC	Unknown	25642631	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +92 more
		SRGAP3	Unknown	25642631	Open Targets	Axon guidance Rho GTPase cycle
		SS18	Unknown	25642631	Open Targets	ATP-dependent chromatin remodeling Transcriptional misregulation in cancer
		SSX1	Unknown	25642631	Open Targets	Transcriptional misregulation in cancer
		STAG1	Unknown	25642631 22820256 22722829	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAG2	Unknown	22820256 22832583 22722829	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAT3	Unknown	25642631 22722829	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		STAT5B	Unknown	25642631 22722829	Open Targets	ErbB signaling pathway Chemokine signaling pathway Hormone signaling +28 more
		STAT6	Unknown	25642631	Open Targets	Necroptosis JAK-STAT signaling pathway Th1 and Th2 cell differentiation +7 more
		STIL	Unknown	22820256	Open Targets	—
		STK11	Unknown	34301788	Open Targets	FoxO signaling pathway Hormone signaling Autophagy - animal +9 more
		SUFU	Unknown	25642631 22820256	Open Targets	Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma +4 more
		SUZ12	Unknown	22820256	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +5 more
		SYK	Unknown	25642631 22722829	Open Targets	NF-kappa B signaling pathway Phospholipase D signaling pathway PI3K-Akt signaling pathway +30 more
		TAL1	Unknown	22722829	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs
		TCF12	Unknown	22722829	Open Targets	Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription
		TCF3	Unknown	25642631	Open Targets	Signaling pathways regulating pluripotency of stem cells Human T-cell leukemia virus 1 infection Transcriptional misregulation in cancer +2 more

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Central nervous system primitive neuroectodermal neoplasm

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