Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
cecum adenocarcinoma	MONDO_0006028	CDH11	Unknown	22810696 25344691	Open Targets	Adherens junctions interactions
		CDH17	Unknown	22810696	Open Targets	Gastric cancer Adherens junctions interactions
		CDK12	Unknown	38725616 26336987 25344691 28481359	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDK4	Unknown	22810696 29316426 28481359	Open Targets	Endocrine resistance Cell cycle p53 signaling pathway +40 more
		CDK6	Unknown	28481359	Open Targets	Cell cycle p53 signaling pathway PI3K-Akt signaling pathway +27 more
		CDKN1A	Unknown	22810696 29316426 28481359	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDKN1B	Unknown	22810696 28481359 25344691	Open Targets	Endocrine resistance ErbB signaling pathway HIF-1 signaling pathway +28 more
		CDKN2A	Unknown	22810696 30239619 29316426 28481359	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CEBPA	Unknown	28481359	Open Targets	Non-alcoholic fatty liver disease Pathways in cancer Transcriptional misregulation in cancer +3 more
		CEP43	Unknown	22810696	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		CEP89	Unknown	22810696	Open Targets	Anchoring of the basal body to the plasma membrane
		CHD2	Unknown	30239619 25344691	Open Targets	—
		CHD4	Unknown	22810696 25344691 27612425	Open Targets	ATP-dependent chromatin remodeling Human papillomavirus infection Viral carcinogenesis +5 more
		CHEK2	Unknown	29316426 28481359	Open Targets	Cell cycle p53 signaling pathway Cellular senescence +9 more
		CHIC2	Unknown	22810696	Open Targets	—
		CHST11	Unknown	22810696	Open Targets	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate Chondroitin sulfate biosynthesis
		CIC	Unknown	29967250 27612425 26336987 29316426 29844865 38725616 28481359	Open Targets	Spinocerebellar ataxia
		CIITA	Unknown	22810696	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CLIP1	Unknown	22810696	Open Targets	mTOR signaling pathway Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids +5 more
		CLP1	Unknown	22810696	Open Targets	mRNA surveillance pathway tRNA processing in the nucleus mRNA Splicing - Major Pathway +3 more
		CLTC	Unknown	22810696 25344691 38725616	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CLTCL1	Unknown	38725616 25344691	Open Targets	Lysosome Endocytosis Synaptic vesicle cycle +8 more
		CNBD1	Unknown	22810696 25344691	Open Targets	—
		CNBP	Unknown	25344691	Open Targets	—
		CNOT3	Unknown	25344691	Open Targets	RNA degradation Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
		CNTNAP2	Unknown	30038269 26336987 25344691	Open Targets	Cell adhesion molecules
		CNTRL	Unknown	22810696	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		COL1A1	Unknown	22810696 26336987	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL2A1	Unknown	22810696 30239619 25344691	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL3A1	Unknown	38725616 26764183 25344691	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CPEB3	Unknown	22810696	Open Targets	Oocyte meiosis Progesterone-mediated oocyte maturation
		CREB1	Unknown	22810696	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Efferocytosis +53 more
		CREBBP	Unknown	22810696 29316426 25344691 28481359	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRLF2	Unknown	28481359	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-7 signaling
		CRNKL1	Unknown	30239619 25344691	Open Targets	Spliceosome mRNA Splicing - Major Pathway
		CRTC1	Unknown	25344691	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSF1R	Unknown	29316426 25344691 28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CSF3R	Unknown	22810696 26336987 28481359	Open Targets	Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway JAK-STAT signaling pathway +3 more
		CSMD3	Unknown	22810696 26336987 25344691 16959974	Open Targets	—
		CTCF	Unknown	29967250 25344691 28481359 38725616	Open Targets	—
		CTNNA1	Unknown	22810696 26336987 25344691 38725616	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +9 more
		CTNNA2	Unknown	22810696 25344691	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +6 more
		CTNNB1	Unknown	22810696 16162961 29316426 11746989 27543871 28978093 28548127 25344691 23471846 38725616 20544848 28481359	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND1	Unknown	25344691	Open Targets	Rap1 signaling pathway Adherens junction Leukocyte transendothelial migration +3 more
		CTNND2	Unknown	22810696 26336987 25344691	Open Targets	Wnt signaling pathway
		CUL3	Unknown	28481359 25344691	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		CUX1	Unknown	22810696 25344691	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		CYLD	Unknown	30239619	Open Targets	NF-kappa B signaling pathway Necroptosis Osteoclast differentiation +9 more
		CYSLTR2	Unknown	25344691	Open Targets	Calcium signaling pathway Neuroactive ligand-receptor interaction Glucagon signaling in metabolic regulation +6 more
		DAXX	Unknown	38725616 29316426 28481359	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more

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Cecum adenocarcinoma

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