Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
cecum adenocarcinoma	MONDO_0006028	FADD	Unknown	25344691	Open Targets	Platinum drug resistance Apoptosis Apoptosis - multiple species +36 more
		FAM131B	Unknown	22810696	Open Targets	Signaling by BRAF and RAF fusions
		FAM135B	Unknown	22810696 25344691	Open Targets	—
		FAM47C	Unknown	38725616 30239619 25344691 22810696 27612425	Open Targets	—
		FANCA	Unknown	29967250 28481359 26336987 25344691 29316426	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCD2	Unknown	22810696	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
		FANCF	Unknown	25344691	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCG	Unknown	25344691	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FAT1	Unknown	22810696 28481359 29316426 25344691 28551381	Open Targets	—
		FAT3	Unknown	22810696 25344691	Open Targets	—
		FAT4	Unknown	22810696 28551381 25344691 38725616 27612425	Open Targets	Hippo signaling pathway - multiple species
		FBLN2	Unknown	22810696	Open Targets	Cytoskeleton in muscle cells Molecules associated with elastic fibres
		FBXO11	Unknown	22810696 27612425 29316426 30387329 25344691 29844865 25370038 28481359 10786688	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	22810696 26650777 27612425 26336987 29316426 25344691 38725616 28481359	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FCGR2B	Unknown	22810696	Open Targets	Virion - Ebolavirus, Lyssavirus and Morbillivirus Phagosome Osteoclast differentiation +6 more
		FCRL4	Unknown	22810696 25344691	Open Targets	—
		FES	Unknown	25344691	Open Targets	Axon guidance Signaling by SCF-KIT Sema3A PAK dependent Axon repulsion +1 more
		FGFR1	Unknown	22810696 28481359 25344691 29967250	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +32 more
		FGFR2	Unknown	28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FGFR3	Unknown	28481359 25344691 29844865 25623536	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +27 more
		FGFR4	Unknown	22810696 29316426 25344691 28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +20 more
		FH	Unknown	28481359	Open Targets	Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways +5 more
		FHIT	Unknown	22810696 25344691	Open Targets	Purine metabolism Metabolic pathways Small cell lung cancer +1 more
		FIP1L1	Unknown	22810696	Open Targets	mRNA surveillance pathway Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway +4 more
		FKBP9	Unknown	22810696	Open Targets	—
		FLCN	Unknown	29316426 28481359 30239619 26336987 25344691	Open Targets	mTOR signaling pathway Renal cell carcinoma Amino acids regulate mTORC1
		FLI1	Unknown	22810696	Open Targets	Transcriptional misregulation in cancer
		FLNA	Unknown	25344691	Open Targets	MAPK signaling pathway Focal adhesion Salmonella infection +6 more
		FLT3	Unknown	28481359 25344691 29844865	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FLT4	Unknown	29316426 28481359 26336987 25344691 26764183	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FNBP1	Unknown	22810696	Open Targets	Shigellosis Clathrin-mediated endocytosis
		FOXA1	Unknown	28481359	Open Targets	Estrogen-dependent gene expression
		FOXL2	Unknown	29316426 28481359	Open Targets	SUMOylation of transcription factors
		FOXO1	Unknown	22810696 28481359	Open Targets	FoxO signaling pathway AMPK signaling pathway Longevity regulating pathway +23 more
		FOXO4	Unknown	25344691	Open Targets	Ras signaling pathway FoxO signaling pathway Shigellosis +7 more
		FOXP1	Unknown	28481359	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FUBP1	Unknown	22810696 28481359	Open Targets	—
		FUS	Unknown	25344691	Open Targets	mRNA surveillance pathway Spliceosome Amyotrophic lateral sclerosis +3 more
		GATA1	Unknown	28481359 29316426 25344691	Open Targets	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GATA2	Unknown	29316426 25344691 28481359	Open Targets	RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GATA3	Unknown	28481359	Open Targets	Th1 and Th2 cell differentiation Th17 cell differentiation Parathyroid hormone synthesis, secretion and action +6 more
		GLI1	Unknown	22810696 29316426 25344691 28481359	Open Targets	cAMP signaling pathway Hedgehog signaling pathway Pathways in cancer +5 more
		GMPS	Unknown	25344691	Open Targets	Purine metabolism Drug metabolism - other enzymes Metabolic pathways +2 more
		GNA11	Unknown	28481359 25344691 29844865	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Hormone signaling +23 more
		GNAQ	Unknown	22810696 28481359	Open Targets	Rap1 signaling pathway Calcium signaling pathway cGMP-PKG signaling pathway +52 more
		GNAS	Unknown	22810696 24470207 26336987 25344691 23471846 28481359	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		GOPC	Unknown	22810696	Open Targets	RHO GTPases regulate CFTR trafficking
		GPC3	Unknown	25344691	Open Targets	Proteoglycans in cancer A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis +9 more
		GPC5	Unknown	22810696 25344691	Open Targets	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation +7 more
		GPHN	Unknown	22810696	Open Targets	Folate biosynthesis Metabolic pathways Biosynthesis of cofactors +2 more

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Cecum adenocarcinoma

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