Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BREAST CANCER	MONDO_0007254 114480 MONDO:0007254	THBS3	Unknown	37636041	GWAS catalog	Phagosome PI3K-Akt signaling pathway Focal adhesion +5 more
		THSD7B	Unknown	40229280	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		THUMPD2	Unknown	40229280	GWAS catalog	—
		TIAL1	Unknown	29059683	GWAS catalog	FGFR2 alternative splicing
		TLR1	Unknown	29059683 32139696 36819030	GWAS catalog	Toll-like receptor signaling pathway Tuberculosis ER-Phagosome pathway +6 more
		TLR10	Unknown	36819030	GWAS catalog	Toll Like Receptor 10 (TLR10) Cascade IRAK4 deficiency (TLR5) MyD88 cascade initiated on plasma membrane
		TMEM151A	Unknown	29059683	GWAS catalog	—
		TMEM178A	Unknown	40229280	GWAS catalog	—
		TMEM182	Unknown	38538606	GWAS catalog	—
		TMEM273	Unknown	38538606	GWAS catalog	—
		TMEM69	Unknown	29059683	GWAS catalog	—
		TNFAIP8L1	Unknown	38538606	GWAS catalog	PI Metabolism
		TNFRSF9	Unknown	29059683	GWAS catalog	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFSF10	Unknown	28171663	GWAS catalog	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +13 more
		TNNT3	Unknown	20453838	GWAS catalog	Motor proteins Cytoskeleton in muscle cells Striated Muscle Contraction
		TNRC6B	Unknown	29059683 37380357 38538606	GWAS catalog	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence +12 more
		TNS1	Unknown	29059683	GWAS catalog	—
		TOP6BL	Unknown	29059683	GWAS catalog	—
		TOX3	Unknown	24493630 25956309 35267517 37380357 37851288	GWAS catalog	—
		TP53	Unknown	—	GenCC, HPO	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TP63	Unknown	38538606	GWAS catalog	MicroRNAs in cancer Activation of PUMA and translocation to mitochondria TP53 Regulates Metabolic Genes +5 more
		TPCN2	Unknown	29059683	GWAS catalog	Calcium signaling pathway Pancreatic secretion Stimuli-sensing channels
		TPK1	Unknown	29059683	GWAS catalog	Thiamine metabolism Metabolic pathways Biosynthesis of cofactors +1 more
		TPRG1L	Unknown	39753771	GWAS catalog	—
		TRAF3	Unknown	29059683	GWAS catalog	NF-kappa B signaling pathway Toll-like receptor signaling pathway NOD-like receptor signaling pathway +25 more
		TRAK2	Unknown	29059683	GWAS catalog	GABAergic synapse
		TRDN	Unknown	38538606	GWAS catalog	Calcium signaling pathway Cardiac muscle contraction Stimuli-sensing channels +1 more
		TRIL	Unknown	29059683	GWAS catalog	—
		TRIM31	Unknown	29059683	GWAS catalog	Interferon gamma signaling
		TRIM38	Unknown	36819030	GWAS catalog	Interferon gamma signaling
		TRIM46	Unknown	29059683 32139696 36819030 37636041	GWAS catalog	Interferon gamma signaling
		TRPS1	Unknown	29059683 32424353 37380357	GWAS catalog	—
		TSGA10IP	Unknown	29059683	GWAS catalog	—
		TSPAN16	Unknown	29058716	GWAS catalog	—
		TTBK1	Unknown	29059683	GWAS catalog	—
		TTC28	Unknown	29059683 30104761 32808324 32887889 34594039 34737426 36819030 37340002 37380357 37636041 38538606 39789286	GWAS catalog	—
		TTLL1	Unknown	29059683	GWAS catalog	—
		TXK	Unknown	29059683 37340002	GWAS catalog	Leukocyte transendothelial migration FCERI mediated Ca+2 mobilization
		UBE2U	Unknown	29059683	GWAS catalog	Ubiquitin mediated proteolysis Antigen processing: Ubiquitination & Proteasome degradation
		UNC13C	Unknown	40229280	GWAS catalog	Synaptic vesicle cycle
		USHBP1	Unknown	20852631 22976474 23535733 25751625 27117709	GWAS catalog	—
		USP22	Unknown	40229280	GWAS catalog	Ub-specific processing proteases
		USP28	Unknown	29059683	GWAS catalog	Ub-specific processing proteases
		USP31	Unknown	37380357	GWAS catalog	—
		UTS2	Unknown	29059683	GWAS catalog	Neuroactive ligand-receptor interaction Peptide ligand-binding receptors G alpha (q) signalling events
		VGLL3	Unknown	29059683	GWAS catalog	—
		VLDLR	Unknown	34290314	GWAS catalog	Spinocerebellar ataxia Lipid and atherosclerosis Reelin signalling pathway +2 more
		VMP1	Unknown	29059683 37340002	GWAS catalog	Autophagy - animal
		VSX2	Unknown	40229280	GWAS catalog	—
		WDR11	Unknown	29059683	GWAS catalog	—
BREAST CARCINOMA	EFO_0000305	THSD7B	Unknown	40229280	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		THUMPD2	Unknown	40229280	GWAS catalog	—
		TIAL1	Unknown	29059683	GWAS catalog	FGFR2 alternative splicing
		TLR1	Unknown	29059683 32139696	GWAS catalog	Toll-like receptor signaling pathway Tuberculosis ER-Phagosome pathway +6 more
		TMEM151A	Unknown	29059683	GWAS catalog	—
		TMEM178A	Unknown	40229280	GWAS catalog	—
		TMEM182	Unknown	38538606	GWAS catalog	—
		TMEM273	Unknown	38538606	GWAS catalog	—
		TMEM69	Unknown	29059683	GWAS catalog	—
		TNFAIP8L1	Unknown	38538606	GWAS catalog	PI Metabolism
		TNFRSF9	Unknown	29059683	GWAS catalog	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNFSF10	Unknown	28171663	GWAS catalog	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +13 more
		TNNT3	Unknown	20453838	GWAS catalog	Motor proteins Cytoskeleton in muscle cells Striated Muscle Contraction
		TNRC6B	Unknown	29059683 35803233 38538606	GWAS catalog	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence +12 more
		TNS1	Unknown	29059683	GWAS catalog	—
		TOP6BL	Unknown	29059683	GWAS catalog	—
		TOX3	Unknown	24493630 25956309 32887889 35267517 37340002 37851288	GWAS catalog	—
		TP63	Unknown	38538606	GWAS catalog	MicroRNAs in cancer Activation of PUMA and translocation to mitochondria TP53 Regulates Metabolic Genes +5 more
		TPCN2	Unknown	27432226 29059683	GWAS catalog	Calcium signaling pathway Pancreatic secretion Stimuli-sensing channels
		TPK1	Unknown	29059683	GWAS catalog	Thiamine metabolism Metabolic pathways Biosynthesis of cofactors +1 more
		TPRG1L	Unknown	39753771	GWAS catalog	—
		TRAF3	Unknown	29059683	GWAS catalog	NF-kappa B signaling pathway Toll-like receptor signaling pathway NOD-like receptor signaling pathway +25 more
		TRAK2	Unknown	29059683 34290314	GWAS catalog	GABAergic synapse
		TRDN	Unknown	38538606	GWAS catalog	Calcium signaling pathway Cardiac muscle contraction Stimuli-sensing channels +1 more
		TRIL	Unknown	29059683	GWAS catalog	—
		TRIM31	Unknown	29059683 38263039	GWAS catalog	Interferon gamma signaling
		TRIM46	Unknown	29059683 32139696 37340002	GWAS catalog	Interferon gamma signaling
		TRPS1	Unknown	29059683 32424353	GWAS catalog	—
		TSGA10IP	Unknown	29059683	GWAS catalog	—
		TSPAN16	Unknown	29058716	GWAS catalog	—
		TTBK1	Unknown	29059683	GWAS catalog	—
		TTC28	Unknown	29059683 32808324 32887889 34594039 34737426 37340002 38538606 39789286	GWAS catalog	—
		TTLL1	Unknown	29059683	GWAS catalog	—
		TXK	Unknown	29059683 37340002	GWAS catalog	Leukocyte transendothelial migration FCERI mediated Ca+2 mobilization
		UBE2U	Unknown	29059683	GWAS catalog	Ubiquitin mediated proteolysis Antigen processing: Ubiquitination & Proteasome degradation
		UNC13C	Unknown	40229280	GWAS catalog	Synaptic vesicle cycle
		USHBP1	Unknown	20852631 22976474 23535733 23544013 25751625 27117709 27197191	GWAS catalog	—
		USP22	Unknown	40229280	GWAS catalog	Ub-specific processing proteases
		USP28	Unknown	29059683	GWAS catalog	Ub-specific processing proteases
		UTS2	Unknown	29059683	GWAS catalog	Neuroactive ligand-receptor interaction Peptide ligand-binding receptors G alpha (q) signalling events
		VGLL3	Unknown	29059683	GWAS catalog	—
		VLDLR	Unknown	34290314	GWAS catalog	Spinocerebellar ataxia Lipid and atherosclerosis Reelin signalling pathway +2 more
		VMP1	Unknown	29059683 37340002	GWAS catalog	Autophagy - animal
		VSX2	Unknown	40229280	GWAS catalog	—
		WDR11	Unknown	29059683	GWAS catalog	—
LUMINAL A BREAST CARCINOMA	MONDO_0021116	TNFSF10	Unknown	38832928	GWAS catalog	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor FoxO signaling pathway +13 more
LUMINAL A BREAST CARCINOMA	MONDO_0021116	TOX3	Unknown	37851288	GWAS catalog	—

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Breast cancer

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