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Bladder clear cell adenocarcinoma
Bladder clear cell adenocarcinoma
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Subtype of:
Bladder cancer
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
bladder clear cell adenocarcinoma
MONDO_0003386
APC
Unknown
31372739
Open Targets
Wnt signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Cushing syndrome
Alzheimer disease
Pathways of neurodegeneration - multiple diseases
Human papillomavirus infection
Pathways in cancer
MicroRNAs in cancer
Colorectal cancer
Endometrial cancer
Basal cell carcinoma
Breast cancer
Hepatocellular carcinoma
Gastric cancer
Apoptotic cleavage of cellular proteins
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Deactivation of the beta-catenin transactivating complex
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Misspliced GSK3beta mutants stabilize beta-catenin
S33 mutants of beta-catenin aren't phosphorylated
S37 mutants of beta-catenin aren't phosphorylated
S45 mutants of beta-catenin aren't phosphorylated
T41 mutants of beta-catenin aren't phosphorylated
APC truncation mutants are not K63 polyubiquitinated
APC truncation mutants have impaired AXIN binding
AXIN missense mutants destabilize the destruction complex
Truncations of AMER1 destabilize the destruction complex
Ovarian tumor domain proteases
+28 more
AR
Unknown
31372739
Open Targets
Oocyte meiosis
Pathways in cancer
Chemical carcinogenesis - receptor activation
Prostate cancer
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
RUNX2 regulates osteoblast differentiation
+7 more
MSH2
Unknown
31372739
Open Targets
Platinum drug resistance
Mismatch repair
Pathways in cancer
Colorectal cancer
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Defective Mismatch Repair Associated With MSH3
Defective Mismatch Repair Associated With MSH2
Defective Mismatch Repair Associated With MSH6
TP53 Regulates Transcription of DNA Repair Genes
+7 more
All
3
Causal
0
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
3
Related Diseases
Diseases that share the most curated genes with Bladder clear cell adenocarcinoma.
5
View disease cluster →
Turcot syndrome
2 shared genes
MSH2, APC
Related via 2 shared genes including MSH2, APC.
Mismatch repair cancer syndrome 2
1 shared gene
MSH2
Related via 1 shared gene including MSH2.
Bulbo-spinal atrophy, x-linked
1 shared gene
AR
Related via 1 shared gene including AR.
Partial androgen insensitivity syndrome
1 shared gene
AR
Related via 1 shared gene including AR.
Kennedy disease
1 shared gene
AR
Related via 1 shared gene including AR.
1
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