Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ATRIAL FIBRILLATION	C0004238 EFO_0000275 MESH:D001281	WDR1	Unknown	29892015 36653681 40050429 40645996	CTD, Disgenet, GWAS catalog	Platelet degranulation
		WDR20	Unknown	40645996	GWAS catalog	Ub-specific processing proteases
		WDR62	Unknown	40050429 40645996	GWAS catalog	—
		WIPF1	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Endocytosis Pathogenic Escherichia coli infection Yersinia infection +3 more
		WNT3	Unknown	30061737 35872910 39537608	CTD, Disgenet, GWAS catalog	mTOR signaling pathway Wnt signaling pathway Hippo signaling pathway +15 more
		WNT7A	Unknown	38574792	GWAS catalog	mTOR signaling pathway Wnt signaling pathway Hippo signaling pathway +13 more
		WNT8A	Unknown	22544366 29892015 30061737 34594039 36653681 40645996	CTD, Disgenet, GWAS catalog	mTOR signaling pathway Wnt signaling pathway Hippo signaling pathway +14 more
		XBP1	Unknown	40645996	GWAS catalog	Protein processing in endoplasmic reticulum Non-alcoholic fatty liver disease Alzheimer disease +8 more
		XPO1	Unknown	29892015 40050429 40645996	CTD, Disgenet, GWAS catalog	Ribosome biogenesis in eukaryotes Nucleocytoplasmic transport Viral life cycle - HIV-1 +15 more
		XPO7	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Nucleocytoplasmic transport
		XRN1	Unknown	40645996	GWAS catalog	Ribosome biogenesis in eukaryotes RNA degradation Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA +1 more
		XRN2	Unknown	40645996	GWAS catalog	Ribosome biogenesis in eukaryotes RNA degradation Major pathway of rRNA processing in the nucleolus and cytosol
		XXYLT1	Unknown	29892015 30061737 35872910 36653681 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Other types of O-glycan biosynthesis
		YDJC	Unknown	40645996	GWAS catalog	—
		YPEL2	Unknown	40645996	GWAS catalog	—
		YWHAE	Unknown	30061737 35872910 36653681 39537608 40050429	GWAS catalog	Cell cycle Oocyte meiosis PI3K-Akt signaling pathway +22 more
		ZBTB17	Unknown	40050429	GWAS catalog	Cell cycle Pathways in cancer Transcriptional misregulation in cancer +2 more
		ZBTB38	Unknown	40050429 40645996	GWAS catalog	—
		ZBTB7B	Unknown	39537608	GWAS catalog	—
		ZCCHC8	Unknown	27790247	GWAS catalog	—
		ZFAT	Unknown	29892015 40050429 40645996	GWAS catalog	—
		ZFHX3	Unknown	19597491 19597492 22544366 29892015 30061737 27790247 28416818 28416822 28460022 29290336 33990960 34594039 35872910 36653681 38574792 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
		ZFHX4	Unknown	34594039	GWAS catalog	—
		ZFPM1	Unknown	40050429 40645996	GWAS catalog	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Factors involved in megakaryocyte development and platelet production
		ZFPM2	Unknown	40050429	GWAS catalog	MicroRNAs in cancer Factors involved in megakaryocyte development and platelet production
		ZHX3	Unknown	27790247	GWAS catalog	—
		ZMIZ1	Unknown	36653681 40050429	GWAS catalog	—
		ZMIZ2	Unknown	40645996	GWAS catalog	—
		ZNF131	Unknown	40050429	GWAS catalog	SUMOylation of transcription cofactors
		ZNF133	Unknown	40645996	GWAS catalog	Generic Transcription Pathway
		ZNF148	Unknown	40645996	GWAS catalog	—
		ZNF219	Unknown	40645996	GWAS catalog	—
		ZNF292	Unknown	29892015 34594039 36653681 40050429 40645996	GWAS catalog	—
		ZNF318	Unknown	40645996	GWAS catalog	—
		ZNF385D	Unknown	40050429 40645996	GWAS catalog	—
		ZNF417	Unknown	40645996	GWAS catalog	Generic Transcription Pathway
		ZNF460	Unknown	40050429	GWAS catalog	Generic Transcription Pathway
		ZNF462	Unknown	29892015 40645996	CTD, Disgenet, GWAS catalog	—
		ZNF469	Unknown	40645996	GWAS catalog	—
		ZNF516	Unknown	40645996	GWAS catalog	Thermogenesis
		ZNF638	Unknown	40050429 40645996	GWAS catalog	—
		ZNF664	Unknown	40050429	GWAS catalog	Generic Transcription Pathway
		ZNF678	Unknown	40050429	GWAS catalog	—
		ZNF689	Unknown	36653681	GWAS catalog	Generic Transcription Pathway
		ZNF814	Unknown	40645996	GWAS catalog	—
		ZNF831	Unknown	40645996	GWAS catalog	—
		ZNRF3	Unknown	40645996	GWAS catalog	Wnt signaling pathway Regulation of FZD by ubiquitination
		ZPBP2	Unknown	29892015 30061737 35872910 36653681 39024449 39537608 40645996	CTD, Disgenet, GWAS catalog	—
		ZPR1	Unknown	27790247	GWAS catalog	—
		ZZEF1	Unknown	40645996	GWAS catalog	—
ATRIAL FIBRILLATION, FAMILIAL 1	C1843687	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 10	C3151464	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 11	C3279693	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 12	C3279695	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 13	C3809311	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 14	C3809312	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 15	C4014269	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 2	C1837812	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 3	C1837014	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 4	C1862394	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 5	C1969099	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 6	C2677294	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 7	C2677106	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 8	C2751607 MESH:C567802 MONDO:0013100	ZFHX3	Unknown	—	CTD, ClinVar, Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
ATRIAL FIBRILLATION, FAMILIAL, 9	C3151431	ZFHX3	Unknown	—	Disgenet	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription

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Atrial fibrillation

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