Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ATRIAL FIBRILLATION	EFO_0000275 C0004238 MESH:D001281	TMEM18	Unknown	40050429 41022758	GWAS catalog	—
		TMEM229A	Unknown	40645996	GWAS catalog	—
		TMEM245	Unknown	40645996	GWAS catalog	—
		TMEM273	Unknown	36653681 40050429 40645996	GWAS catalog	—
		TMEM91	Unknown	40645996	GWAS catalog	—
		TMT1B	Unknown	30061737	GWAS catalog	—
		TNFSF12	Unknown	30061737 35872910 39024449 39537608	CTD, Disgenet, GWAS catalog	Cytokine-cytokine receptor interaction TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
		TNFSF12-TNFSF13	Unknown	30061737 35872910 39024449 39537608	GWAS catalog	TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
		TNN	Unknown	40645996	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +3 more
		TNNI3K	Unknown	40645996	GWAS catalog	—
		TNPO1	Unknown	40645996	GWAS catalog	Nucleocytoplasmic transport Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Intraflagellar transport
		TNRC6A	Unknown	40645996	GWAS catalog	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence +13 more
		TNS1	Unknown	40645996	GWAS catalog	—
		TOMM7	Unknown	40645996	GWAS catalog	Mitophagy - animal Pink/Parkin Mediated Mitophagy
		TOP2B	Unknown	40645996	GWAS catalog	Platinum drug resistance SUMOylation of DNA replication proteins
		TRA2B	Unknown	40645996	GWAS catalog	Spliceosome Alcoholic liver disease mRNA Splicing - Major Pathway
		TRAP1	Unknown	40645996	GWAS catalog	Parkinson disease Pathways of neurodegeneration - multiple diseases
		TRIB1	Unknown	27790247	GWAS catalog	NGF-stimulated transcription
		TRIB2	Unknown	40645996	GWAS catalog	—
		TRIM36	Unknown	39537608 40050429	GWAS catalog	Antigen processing: Ubiquitination & Proteasome degradation
		TRIM48	Unknown	40645996	GWAS catalog	Interferon gamma signaling
		TRIOBP	Unknown	40050429	GWAS catalog	—
		TRPC3	Unknown	40645996	GWAS catalog	Axon guidance Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases +3 more
		TRPM2	Unknown	40645996	GWAS catalog	NOD-like receptor signaling pathway Oxytocin signaling pathway TRP channels +1 more
		TSNARE1	Unknown	40645996	GWAS catalog	—
		TSPAN14	Unknown	40645996	GWAS catalog	Neutrophil degranulation Amyloid fiber formation
		TSPAN8	Unknown	40645996	GWAS catalog	—
		TTC34	Unknown	40645996	GWAS catalog	—
		TTN	Unknown	29290336 29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Dilated cardiomyopathy +2 more
		TUBA8	Unknown	29892015 30061737 34594039 35872910 36653681 39024449 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Phagosome Apoptosis Tight junction +31 more
		TUT7	Unknown	40645996	GWAS catalog	Deadenylation of mRNA
		TWIST1	Unknown	40645996	GWAS catalog	Proteoglycans in cancer Interleukin-4 and Interleukin-13 signaling Regulation of RUNX2 expression and activity
		UBAP2	Unknown	40645996	GWAS catalog	—
		UBE2D3	Unknown	36653681 40645996	GWAS catalog	Polycomb repressive complex Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum +10 more
		UBE2L3	Unknown	40050429 40645996	GWAS catalog	Ubiquitin mediated proteolysis Parkinson disease Pathways of neurodegeneration - multiple diseases +3 more
		UBE4B	Unknown	29892015 39024449	CTD, Disgenet, GWAS catalog	Ubiquitin mediated proteolysis Protein processing in endoplasmic reticulum
		UBR5	Unknown	40645996	GWAS catalog	Ubiquitin mediated proteolysis
		USP28	Unknown	40050429 40645996	GWAS catalog	Ub-specific processing proteases
		USP3	Unknown	29892015 40050429	CTD, Disgenet, GWAS catalog	Ub-specific processing proteases
		USP34	Unknown	30061737 35872910 36653681 39537608	CTD, Disgenet, GWAS catalog	TCF dependent signaling in response to WNT Ub-specific processing proteases
		USP36	Unknown	40645996	GWAS catalog	—
		UST	Unknown	29892015 30061737 34594039 35872910 36653681 39537608 40050429 40645996	CTD, Disgenet, GWAS catalog	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate Dermatan sulfate biosynthesis
		VEGFA	Unknown	40050429	GWAS catalog	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
		VGLL2	Unknown	34594039 40050429 40645996 41022758	GWAS catalog	—
		VGLL4	Unknown	40645996	GWAS catalog	—
		VPS37B	Unknown	40050429 40645996	GWAS catalog	Endocytosis Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins +2 more
		VPS37D	Unknown	27790247	GWAS catalog	Endocytosis Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins +2 more
		VRTN	Unknown	40645996	GWAS catalog	—
		VWA7	Unknown	40645996	GWAS catalog	—
		VWF	Unknown	17890461	CTD, Disgenet	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +20 more

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Atrial fibrillation

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