Anaplastic large cell lymphoma | Gene-Disease Associations & Pathways | GeDiPNet

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Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
anaplastic large cell lymphoma	MONDO_0020325	PMS1	Unknown	34382383	Open Targets	—
		PMS2	Unknown	27203213	Open Targets	Mismatch repair Fanconi anemia pathway Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) +3 more
		PRDM1	Unknown	24004669	Open Targets	Regulation of TP53 Expression
		PRDM16	Unknown	34382383	Open Targets	Lysine degradation Metabolic pathways Thermogenesis +1 more
		PTPRD	Unknown	27203213 34382383	Open Targets	Cell adhesion molecules Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
		RET	Unknown	34382383	Open Targets	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway +6 more
		RGS7	Unknown	34382383	Open Targets	G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
		SALL4	Unknown	34382383	Open Targets	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells Regulation of PTEN gene transcription
		SBDS	Unknown	27203213	Open Targets	Ribosome biogenesis in eukaryotes
		SETD2	Unknown	28481359	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SND1	Unknown	34382383	Open Targets	Viral carcinogenesis Signaling by BRAF and RAF fusions
		SPEN	Unknown	28481359	Open Targets	Notch signaling pathway
		STAT3	Unknown	23563237 23872306 27203213 28356514	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		TBL1XR1	Unknown	22855598	Open Targets	Wnt signaling pathway RORA activates gene expression PPARA activates gene expression +11 more
		TET2	Unknown	29386642 26268241	Open Targets	—
		TFG	Unknown	11943732 10556217 11310834 17464320 19545284	Open Targets	Pathways in cancer Thyroid cancer COPII-mediated vesicle transport
		TGFBR2	Unknown	34382383	Open Targets	MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway +28 more
		TP53	Unknown	8103295 27203213 15990866 7756655 22855598 10084308 29386642	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TP63	Unknown	22855598	Open Targets	MicroRNAs in cancer Activation of PUMA and translocation to mitochondria TP53 Regulates Metabolic Genes +5 more
		TPM3	Unknown	12707379 17464320 10216106 11493472 10610119 19545284 11310834 19135051	Open Targets	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +7 more
		TPM4	Unknown	11493472	Open Targets	Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Motor proteins +5 more
		TRAF7	Unknown	27203213	Open Targets	Antigen processing: Ubiquitination & Proteasome degradation
		TRRAP	Unknown	34382383	Open Targets	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection Formation of the beta-catenin:TCF transactivating complex +1 more
		WNK2	Unknown	34382383	Open Targets	Parathyroid hormone synthesis, secretion and action Stimuli-sensing channels

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