Subtype of: Meningioma

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
Anaplastic (Malignant) Meningioma	EFO_1000082	LEF1	Unknown	28713588	Open Targets	Wnt signaling pathway Hippo signaling pathway Adherens junction +24 more
		LEPROTL1	Unknown	28713588	Open Targets	—
		LIFR	Unknown	28713588	Open Targets	Cytokine-cytokine receptor interaction Signaling pathways regulating pluripotency of stem cells JAK-STAT signaling pathway +2 more
		LMNA	Unknown	30123936	Open Targets	Apoptosis Cytoskeleton in muscle cells Hypertrophic cardiomyopathy +8 more
		LOC100506403	Unknown	28713588	Open Targets	—
		LOC105376156	Unknown	28713588	Open Targets	—
		LPP	Unknown	28713588	Open Targets	—
		LRP1B	Unknown	28713588	Open Targets	—
		LZTR1	Unknown	28713588	Open Targets	—
		MALT1	Unknown	28713588	Open Targets	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway +8 more
		MAP3K1	Unknown	28713588	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MAP3K13	Unknown	28713588	Open Targets	MAPK signaling pathway
		MAPK1	Unknown	28713588	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +161 more
		MB21D2	Unknown	28713588	Open Targets	—
		MDM2	Unknown	28713588	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MECOM	Unknown	28713588	Open Targets	Lysine degradation Metabolic pathways MAPK signaling pathway +4 more
		MET	Unknown	28713588	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MGMT	Unknown	28713588	Open Targets	MGMT-mediated DNA damage reversal
		MLLT3	Unknown	28713588	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MSH2	Unknown	28713588	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MSI2	Unknown	28713588	Open Targets	mRNA surveillance pathway
		MSN	Unknown	28713588	Open Targets	Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton +4 more
		MTOR	Unknown	28713588	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC16	Unknown	28713588	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC4	Unknown	28713588	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC6	Unknown	28713588	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MYB	Unknown	28713588	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYH11	Unknown	28713588	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		MYH9	Unknown	28713588	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +8 more
		MYO5A	Unknown	28713588	Open Targets	Motor proteins Pathogenic Escherichia coli infection Regulation of actin dynamics for phagocytic cup formation +1 more
		N4BP2	Unknown	28713588	Open Targets	—
		NACA	Unknown	25963524 28713588	Open Targets	Parathyroid hormone synthesis, secretion and action
		NBEA	Unknown	28713588	Open Targets	—
		NCOA1	Unknown	28713588	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway Pathways in cancer +18 more
		NCOA2	Unknown	28713588	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway RORA activates gene expression +14 more
		NCOR1	Unknown	28713588	Open Targets	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NCOR2	Unknown	28713588	Open Targets	Notch signaling pathway Epstein-Barr virus infection PPARA activates gene expression +11 more
		NDRG1	Unknown	28713588	Open Targets	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
		NF1	Unknown	28713588	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		NF2	Unknown	11668501 27548314 28713588 10901233 30123936 9126902 17222329 7717450 28481359	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Tight junction +2 more
		NFATC2	Unknown	28713588	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Efferocytosis +24 more
		NFE2L2	Unknown	28713588	Open Targets	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NFIB	Unknown	28713588	Open Targets	—
		NOTCH1	Unknown	28713588	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +20 more
		NOTCH2	Unknown	28713588	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NRG1	Unknown	28713588	Open Targets	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more
		NSD2	Unknown	30123936	Open Targets	Lysine degradation Metabolic pathways Transcriptional misregulation in cancer +5 more
		NSD3	Unknown	28713588	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		NTRK2	Unknown	28713588	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more
		NUP98	Unknown	28713588	Open Targets	Nucleocytoplasmic transport Amyotrophic lateral sclerosis Influenza A +33 more

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Anaplastic (malignant) meningioma

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